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An artificial molecular switch that mimics the visual pigment and completes its photocycle in picoseconds (2008)

Abstract
Single mols. that act as light-energy transducers (e.g., converting the energy of a photon into at.-level mech. motion) are examples of minimal mol. devices. Here, we focus on a mol. switch designed by merging a conformationally locked diarylidene skeleton with a retinal-like Schiff base and capable of mimicking, in soln., different aspects of the transduction of the visual pigment Rhodopsin. Complementary ab initio multiconfigurational quantum chem.-based computations and time-resolved spectroscopy are used to follow the light-induced isomerization of the switch in methanol. The results show that, similar to rhodopsin, the isomerization occurs on a 0.3-ps time scale and is followed by

Details der Publikation
Download http://infoscience.epfl.ch/record/134959
Archiv Infoscience | Ecole Polytechnique Federale de Lausanne (Switzerland)
Keywords Molecular modeling; Molecular switches; Simulation and Modeling (artificial mol. switch mimics visual pigment and completes photocycle in picoseconds); Isomerization (photoisomerization; artificial mol. switch mimics visual pigment and completes photocycle in picoseconds); Pigments (visual; artificial mol. switch mimics visual pigment and completes photocycle in picoseconds), mol switch vision pigment photocycle isomerization
Typ Text
Sprache Englisch