| Xenon or propofol anaesthesia for patients at cardiovascular risk in non-cardiac surgery (2008) | |||||||||||||
Abstract | |||||||||||||
| Background The results of two European multi-centre trials on xenon anaesthesia led to the hypothesis that a xenon-based anaesthetic would keep left ventricular (LV) and circulatory function more stable than a propofol-based anaesthetic, in patients with coronary artery disease (CAD). Methods In a prospective, randomized design, 40 patients of ASA classes III and IV with known CAD were anaesthetized for elective non-cardiac surgery with either xenon (n=20) or propofol (n=20), each combined with remifentanil. Target criteria were intraoperative LV function as evaluated by transoesophageal echocardiography (TOE: Tei index, circumferential fibre shortening), arterial pressure, and heart rate (HR). Results Mean arterial pressure was decreased with propofol but was stable at pre-anaesthetic level with xenon (P | |||||||||||||
Details der Publikation | |||||||||||||
| |||||||||||||