| Time-dependent association of total serum cholesterol and cancer incidence in a cohort of 172 210 men and women: a prospective 19-year follow-up study (2009) | |||||||||||||
Abstract | |||||||||||||
| Background: The relationship between serum cholesterol and cancer incidence remains controversial. Patients and methods: We investigated the association of total serum cholesterol (TSC) with subsequent cancer incidence in a population-based cohort of 172 210 Austrian adults prospectively followed up for a median of 13.0 years. Cox regression, allowing for time-dependent effects, was used to estimate adjusted hazard ratios (HRs) with 95% confidence intervals (95% CIs) for the association of TSC with cancer. Results: We observed pronounced short-term associations of TSC and overall cancer incidence in both men and women. For malignancies diagnosed shortly (235.0 mg/dl in men and >229.0 in women) compared with the lowest tertile ( | |||||||||||||
Details der Publikation | |||||||||||||
| |||||||||||||