| Coalescent-Based Estimation of Population Parameters When the Number of Demes Changes over Time (2006) | |||||||||||||
Abstract | |||||||||||||
| We expand a coalescent-based method that uses serially sampled genetic data from a subdivided population to incorporate changes to the number of demes and patterns of colonization. Often, when estimating population parameters or other parameters of interest from genetic data, the demographic structure and parameters are not constant over evolutionary time. In this paper we develop a Bayesian MCMC method that allows for step changes in mutation, migration, and population sizes, as well as changing numbers of demes, where the times of these changes are also estimated. We show that in parameter ranges of interest, reliable estimates can often be obtained, including the historical times of parameter changes. However posterior densities of migration rates can be quite diffuse and estimators somewhat biased, as reported by other authors. | |||||||||||||
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