| Filtering Heart Related Activity from Vagus Nerve Recordings in Rats (2009) | |||||||||||||
Abstract | |||||||||||||
| Vagus nerve stimulation has become a recognized form of treatment for several conditions such as refractory epilepsy and depression. However, its exact mechanism of interference with these pathologies remains unknown. Vagus nerve signals have recently been recorded in rats in order to gain a better understanding of such situations. Due to the proximity of the recording site to the heart itself and beating arteries, the signal is contaminated by cardiac artifacts. These represent a major challenge to the subsequent extraction of accurate and useful information such as the frequency spectrum or the amplitude of the nerve signal. Efficient ECG contamination removal techniques have been introduced in the literature for the EMG signal. However, to our knowledge, the removal of cardiac activity contamination has never been investigated previously in neurograms. In this work, we investigate the application of these removal techniques on vagus nerve signals. The methods are evaluated on real experimental recordings from the vagus nerve in rats. 1 | |||||||||||||
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