Puren, A J, Fantuzzi, G, Gu, Y, Su, M S, Dinarello, C A
IL-18 is synthesized as a precursor molecule without a signal peptide but requires the IL-1beta converting enzyme (ICE, caspase-1) for cleavage into a mature peptide. Human precursor IL-18 was...
Puren, A J, Fantuzzi, G, Gu, Y, Su, M S, Dinarello, C A
IL-18 is synthesized as a precursor molecule without a signal peptide but requires the IL-1beta converting enzyme (ICE, caspase-1) for cleavage into a mature peptide. Human precursor IL-18 was...
Interleukin 1 receptors and biological responses.
Dinarello, C. A., Clark, B. D., Ikejima, T., Puren, A. J., Savage, N., Rosoff, P. M.
Interleukin 1 (IL-1) is a polypeptide which possesses a wide variety of biological properties. IL-1 was originally studied as "endogenous pyrogen" and "leukocytic endogenous mediator" and more...