Alonso, A., Jacobs, D.R., Menotti, A., Nissinen, A., Dontas, A., Kafatos, A., ...
Previous research shows that cardiovascular risk factors in mid-adulthood could increase the risk of dementia later in life, but studies with very long follow-up are still scarce. We assessed whether...
Kamphuis, M.H., Geerlings, M.I., Giampaoli, S., Nissinen, A., Grobbee, D.E., Kromhout, D.
Background Depression is associated with an increased risk of cardiovascular diseases (CVD) and cardiovascular mortality. We investigated to what extent subjective health status explained the...
Bots, S., Tijhuis, M.J., Giampaoli, S., Kromhout, D., Nissinen, A.
Objective Late-life depression is one of the main health problems among elderly populations and a key element of healthy ageing. Causal relationships of lifestyle- and diet-related factors in...
Boshuizen, H.C., Lanti, M., Menotti, A., Moschandreas, J., Tolonen, H., Nissinen, A., ...
The authors aimed to quantify the effects of current systolic blood pressure (SBP) and serum total cholesterol on the risk of mortality in comparison with SBP or serum cholesterol 25 years...
Menotti, A., Lanti, M., Kromhout, D., Blackburn, H., Jacobs, D., Nissinen, A., ...
Background: The aim was to investigate whether multivariate coefficients of serum cholesterol in the prediction of coronary heart disease (CHD) deaths were similar across different cultures in a...
Buijsse, B., Tijhuis, M., Kalmijn, S., Giampaoli, S., Nissinen, A., ...
Objective: To investigate whether coffee consumption is associated with 10-year cognitive decline in elderly men, as results of previous studies obtained hitherto have been controversial and...
Buijsse, B., Tijhuis, M.J., Kalmijn, S., Giampaoli, S., Nissinen, A., ...
Objective: To investigate whether coffee consumption is associated with 10-year cognitive decline in elderly men, as results of previous studies obtained hitherto have been controversial and...
Boshuizen, H.C., Lanti, M., Menotti, A., Moschandreas, J., Tolonen, H., Nissinen, A., ...
The authors aimed to quantify the effects of current systolic blood pressure (SBP) and serum total cholesterol on the risk of mortality in comparison with SBP or serum cholesterol 25 years...
Autonomic dysfunction: a link between depression and cardiovascular mortality? The FINE Study (2007)
Kamphuis, M.H., Geerlings, M.I., Dekker, J.M., Giampaoli, S., Nissinen, A., Grobbee, D.E., ...
Background: Depression is associated with an increased risk of cardiovascular diseases (CVD) in vascular patients as well as in the general population. We investigated whether autonomic dysfunction...
Menotti, A., Lanti, M., Kromhout, D., Blackburn, H., Nissinen, A., Dontas, A., ...
Time trends in coronary heart disease (CHD) mortality during a 40-year follow-up were studied in the Seven Countries Study. Thirteen cohorts of men aged 40¿59 at entry were enrolled in seven...
Lupisan, S. P., Ruutu, P., Quiambao, B. P., Gozum, L., Sombrero, L. T., ...
Objective: To determine predictors of death among children 2-59 months old admitted to hospital with severe pneumonia. Methods: Prospective observational study from April 1994 to May 2000 to...
Physical inactivity, depression, and risk of cardiovascular mortality (2007)
Kamphuis, M.H., Geerlings, M.I., Tijhuis, M.A.R., Giampaoli, S., Nissinen, A., Grobbee, D.E., ...
Kamphuis, M.H., Kalmijn, S., Tijhuis, M.A.R., Geerlings, M.I., Giampaoli, S., Nissinen, A., ...
BACKGROUND: Depressive symptoms have been suggested to increase the risk of cardiovascular diseases, but this may reflect reversed causality. We investigated to what extent depressive symptoms are a...
Tijhuis, M.A.R., Aijanseppa, S., Nissinen, A., Giampaoli, S., ...
The objectives were to investigate the predictive value of hierarchy levels and sum score of disability and change in disability on depressive symptoms. Method: Longitudinal data of 723 men age 70...
Tijhuis, M., Aijanseppa, S., Nissinen, A., Giampaoli, S., ...
Objectives: The objectives were to investigate the predictive value of hierarchy levels and sum score of disability and change in disability on depressive symptoms. Method: Longitudinal data of 723...
Tijhuis, M., Kalmijn, S., Giampaoli, S., Nissinen, A., Kromhout, D.
We investigate the association between marital status and living situation (over 5 years) on 10-year subsequent cognitive decline. The study population consisted of 1,042 men aged 70-89 years in...
Developing LCA-based benchmarks for sustainable consumption - for and with users (2005)
Nissinen, A., Heiskanen, E., Grönroos, J., Honkanen, A., Kurppa, S., ...
This article presents the development process of a consumer-oriented, illustrative benchmarking tool enabling consumers to use the results of environmental life cycle assessment (LCA) to make...
Duration and intensity of physical activity and disability among European elderly men (2005)
Picavet, H.S.J., Giampaoli, S., Nissinen, A., Kromhout, D.
PURPOSE: To investigate the relationship between duration and intensity of physical activity and disability 10 years later, and to investigate the possible effect of selective mortality. METHOD:...
Menotti, A., Lanti, M., Kromhout, D., Kafatos, A., Nedeljkovic, S., Nissinen, A.
Aims: The purpose was to study the association of a single serum cholesterol measurement with early and late coronary and other cardiovascular deaths during 35 years of follow-up in samples of men...
Lanti, M., Nedeljkovic, S., Nissinen, A., Kafatos, A., Kromhout, D.
ACKGROUND AND AIMS: Time trends in major cardiovascular risk factors are described in cohorts of middle-aged men followed for 35 years in 9 European cohorts of Finland, The Netherlands, Italy, Serbia...
Menotti, A., Lanti, M., Nedeljkovic, S., Nissinen, A., Kafatos, A., Kromhout, D.
Objective: To explore whether "typical" coronary heart disease (CHD) such as fatal myocardial infarction and sudden death relate to major cardiovascular risk factors in the same way as the "atypical"...
Panagiotakos, DB, Kromhout, D., Menotti, A., Chrysohoou, C., Dontas, A., Pitsavos, C., ...
BACKGROUND: Hypertension is a dominant characteristic in the prediction of cardiovascular diseases (CVDs). We aimed to evaluate the association of blood pressure measurements with CVD mortality among...
Developing LCA-based benchmarks for sustainable consumption - for and with users (2005)
Nissinen, A., Heiskanen, E., Grönroos, J., Honkanen, A., Kurppa, S., ...
This article presents the development process of a consumer-oriented, illustrative benchmarking tool enabling consumers to use the results of environmental life cycle assessment (LCA) to make...
Buijsse, G.M., Kalmijn, S., Tijhuis, M.J., Giampaoli, S., Nissinen, A., ...
Coffee is a daily consumed drink in most Western countries and is the primary source of caffeine. Caffeine intake seems to be beneficial for cognitive function on the short term, however results are...
Climatic effects on litter decomposition from arctic tundra to tropical rainforest. (2004)
Liski, J., Nissinen, A., Erhard, M., Taskinen, O.
Global Change Biology, 9(2003) S.575-84
Tijhuis, M., Kalmijn, S., Klazinga, N.S., Nissinen, A., Giampaoli, S., ...
OBJECTIVES:To compare self-reported disability and performance-based limitation and their association in elderly men from three European countries. DESIGN:Cross-sectional data from a cohort study...
Kramer, K., Leinonen, I., Bartelink, H.H., Berbigier, P., Borghetti, M., Bernhofer, C., ...
Reliable models are required to assess the impacts of climate change on forest ecosystems. Precise and independent data are essential to assess this accuracy. The flux measurements collected by the...
Verenpaine, Käypä hoito suositus (2002)
Suomen Verenpaineyhdistys Ry., Jula, A, Aro, A, Fyhrqvist, F, Keinänen-Kiukaanniemi, S, Koivisto, P, ...
Duodecim 2002; 118(1):110-126.
Qiao, Q., Pyörälä, K., Pyörälä, M., Nissinen, A., Lindström, J., Tilvis, R., ...
Aims To assess the predictive value of fasting and 2-h glucose after a 75g glucose load, with regard to incidence of coronary heart disease and cardiovascular mortality. Methods and Results 6766...
Predicting cardiovascular risk in the elderly in different European countries (2002)
Houterman, S., Boshuizen, H.C., Verschuren, W.M.M., Giampaoli, S., Nissinen, A., Menotti, A., ...
Aims The objective of this study was to develop risk functions for coronary heart disease and cardiovascular disease mortality for elderly men in different European countries. Methods and Results The...
Mulder, I., Smit, H.A., Jacobs, D.R., Menotti, A., Nissinen, A., ...
We examined the role of smoking and diet in the cross-cultural variation in lung-cancer mortality, using aggregated data of the Seven Countries Study, a follow-up study comprising 12,763 middle-aged...
Qiao, Q, Tervahauta, M, Nissinen, A, Tuomilehto, J
Aims The risk of early and late death in relation to smoking and ex-smoking were studied. Methods and Results A cohort of 1711 Finnish men born between 1900 and 1919 were recruited in 1959 and...
Visscher, T. L. S., Seidell, J. C., Menotti, A., Blackburn, H., Nissinen, A., Feskens, E. J. M., ...
This study investigated the relation between body mass index (BMI) and the all-cause mortality rate among 7,985 European men. Starting around 1960, when all men were aged 40–59 years, mortality was...
Dietary patterns and cognitive function in elderly men in Finland, Italy and The Netherlands. (1998)
Feskens, E.J.M., Rasanen, L., Fidanza, F., Alberti-Fidanza, A., Nissinen, A., ...
Size at birth and coronary heart disease mortality in Finns born during 1924-33 (1997)
Forsén, TJ, Tuomilehto, J, Teramo, K, Reunanen, A, Nissinen, A, Osmond, C, ...
Diabetologia 1997; 40: suppl 1: A 213.
Maternal obesity, thinness at birth and coronary heart disease mortality in Finnish males (1997)
Forsén, T, Tuomilehto, J, Teramo, K, Reunanen, A, Nissinen, A, Osmond, C, ...
Abstracts of IDEG satellite symposium of IDF Congress, Savonlinna, 17-20 July 1997.
Diet and cognitive function in elderly men in Finland, Italy, and The Netherlands. (1996)
Feskens, E.J.M., Rasanen, L., Giampaoli, S., Nissinen, A., Fidanza, F., ...
Dietary patterns and 20-year mortality in elderly men in Finland, Italy and the Netherlands. (1995)
Feskens, E.J.M., Rasanen, L., Fidanza, F., Nissinen, A., Menotti, A., ...
Kromhout, D., Menotti, A., Bloemberg, B., Aravanis, C., Blackburn, H., Buzina, R., ...
Background. In the Seven Countries Study associations between intake of individual fatty acids and dietary cholesterol were studied in relation to serum cholesterol and 25-year mortality from...
Is a high serum cholesterol level associated with longer survival in elderly hypertensives? (1990)
Amery, A, Birkenhäger, W, Bulpitt, C, Clement, D, De Leeuw, P, ...
The relationship between serum total cholesterol, measured at randomization, and mortality was investigated in 822 patients, who were followed for an average of 3.1 years in a double-blind trial,...
SALOMAA, V., KORHONEN, H. J., TUOMILEHTO, J., VARTIAINEN, E., PIETINEN, P., KARTOVAARA, L., ...
The serum cholesterol distribution in three geographical areas of Finland was examined during the first and the second FINMONICA surveysin 1982 and1987'. The mean serum cholesterol concentration...
Twenty-Year Stroke Mortality and Prediction in Twelve Cohorts of the Seven Countries Study (1990)
MENOTTI, A, KEYS, A, BLACKBURN, H, ARAVANIS, C, DONTAS, A, FIDANZA, F, ...
Menotti A (Laboratory of Epidemiology and Biostatistics, Istituto Superiore di Sanit�, I-00161, Rome, Italy), Keys A, Blackburn H, Aravanis C, Dontas A, Fidanza F, Giampaoli S, Karvonen M, Kromhout...
Salonen, JT, Tuomilehto, J, Nissinen, A, Kaplan, GA, Puska, P
http://deepblue.lib.umich.edu/bitstream/2027.42/55390/1/Salonen JT, Contribution of Risk Factor, 1989.pdf
Bulpitt, C, Clement, D, De Leeuw, P, Fagard, R, Fletcher, A, ...
TUOMILEHTO, J., SALONEN, J. T., NISSINEN, A.
The prevalence of hypertension in general and of those complications associated with isolated systolic hypertension (at least 165 mmHg systolic and less than 95 mmHg diastolic pressure) were assessed...
Birkenhäger, W, Bogaert, M, Brixko, P, Bulpitt, C, Clement, D, ...
1. Although systolic blood pressure elevation is responsible for increased incidence of cardiovascular accidents in old people, the preventive benefit of lowering systolic hypertension in elderly has...
Berthaux, P, Birkenhäger, W, Boel, A, Brixko, P, Bulpitt, C, ...
Berthaux, P, Birkenhager, W, Boel, A, Brixko, P, Bulpitt, C, ...
Gripenberg, M, Nissinen, A, Väisänen, E, Linder, E
Antibodies against Yersinia enterocolitica serotype O:3 lipopolysaccharide present in sera from patients with Yersinia infection were studied by using an enzyme-linked immunosorbent assay. Of the...
Body weight and risk of myocardial infarction and death in the adult population of eastern Finland.
Tuomilehto, J, Salonen, J T, Marti, B, Jalkanen, L, Puska, P, Nissinen, A, ...
Body mass index (weight (kg) divided by height squared (m2] and its association with the risk of myocardial infarction and death from all causes were studied prospectively in a randomly selected...
Decline in cardiovascular mortality in North Karelia and other parts of Finland.
Tuomilehto, J, Geboers, J, Salonen, J T, Nissinen, A, Kuulasmaa, K, Puska, P
The trends in mortality from ischaemic heart disease, cerebrovascular stroke, and all cardiovascular diseases were analysed for the province of North Karelia and for the rest of Finland. Linear...
Tuomilehto, J, Nissinen, A, Wolf, E, Geboers, J, Piha, T, Puska, P
A study was made of the changes in the treatment of hypertension, in the effectiveness of that treatment, and in mortality from cerebrovascular stroke in men and women in two counties in Finland. One...
Decline in mortality from coronary heart disease in Finland from 1969 to 1979.
Salonen, J T, Puska, P, Kottke, T E, Tuomilehto, J, Nissinen, A
The trends in mortality from coronary heart disease in the 1970s and the differences in trends between counties within Finland were calculated from official mortality statistics among the population...
Puska, P, Salonen, J T, Nissinen, A, Tuomilehto, J, Vartiainen, E, Korhonen, H, ...
A comprehensive community based programme to control cardiovascular diseases was started in North Karelia, Finland, in 1972. Reductions in smoking, serum cholesterol concentrations, and blood...
Puska, P, Tuomilehto, J, Salonen, J, Neittaanmäki, L, Maki, J, Virtamo, J, ...
A comprehensive community programme to control cardiovascular diseases (CVD) in North Karelia, Finland, was carried out during 1972-7. The central intermediate objective of the programme was to...
Kottke, T E, Puska, P, Salonen, J T, Tuomilehto, J, Nissinen, A
To test whether the cardiovascular disease declines in North Karelia were accompanied by subjective improvements in health, we analyzed responses to two questions about perceived risk of heart...
Tuomilehto-Wolf, E, Tuomilehto, J, Hitman, G A, Nissinen, A, Stengård, J, Pekkanen, J, ...
OBJECTIVES--To test the hypothesis that the genetic susceptibility to non-insulin dependent diabetes mellitus is the same as that to insulin dependent disease and to see whether glucose intolerance...
Gripenberg, M, Nissinen, A, Väisänen, E, Linder, E
Antibodies against Yersinia enterocolitica serotype O:3 lipopolysaccharide present in sera from patients with Yersinia infection were studied by using an enzyme-linked immunosorbent assay. Of the...
Body weight and risk of myocardial infarction and death in the adult population of eastern Finland.
Tuomilehto, J, Salonen, J T, Marti, B, Jalkanen, L, Puska, P, Nissinen, A, ...
Body mass index (weight (kg) divided by height squared (m2] and its association with the risk of myocardial infarction and death from all causes were studied prospectively in a randomly selected...
Decline in cardiovascular mortality in North Karelia and other parts of Finland.
Tuomilehto, J, Geboers, J, Salonen, J T, Nissinen, A, Kuulasmaa, K, Puska, P
The trends in mortality from ischaemic heart disease, cerebrovascular stroke, and all cardiovascular diseases were analysed for the province of North Karelia and for the rest of Finland. Linear...
Tuomilehto, J, Nissinen, A, Wolf, E, Geboers, J, Piha, T, Puska, P
A study was made of the changes in the treatment of hypertension, in the effectiveness of that treatment, and in mortality from cerebrovascular stroke in men and women in two counties in Finland. One...
Decline in mortality from coronary heart disease in Finland from 1969 to 1979.
Salonen, J T, Puska, P, Kottke, T E, Tuomilehto, J, Nissinen, A
The trends in mortality from coronary heart disease in the 1970s and the differences in trends between counties within Finland were calculated from official mortality statistics among the population...
Puska, P, Salonen, J T, Nissinen, A, Tuomilehto, J, Vartiainen, E, Korhonen, H, ...
A comprehensive community based programme to control cardiovascular diseases was started in North Karelia, Finland, in 1972. Reductions in smoking, serum cholesterol concentrations, and blood...
Puska, P, Tuomilehto, J, Salonen, J, Neittaanmäki, L, Maki, J, Virtamo, J, ...
A comprehensive community programme to control cardiovascular diseases (CVD) in North Karelia, Finland, was carried out during 1972-7. The central intermediate objective of the programme was to...
Kottke, T E, Puska, P, Salonen, J T, Tuomilehto, J, Nissinen, A
To test whether the cardiovascular disease declines in North Karelia were accompanied by subjective improvements in health, we analyzed responses to two questions about perceived risk of heart...
Tuomilehto-Wolf, E, Tuomilehto, J, Hitman, G A, Nissinen, A, Stengård, J, Pekkanen, J, ...
OBJECTIVES--To test the hypothesis that the genetic susceptibility to non-insulin dependent diabetes mellitus is the same as that to insulin dependent disease and to see whether glucose intolerance...
A pitfall in purulent arthritis brought out in Kingella kingae infection of the knee.
Salminen, I, Von Essen, R, Koota, K, Nissinen, A
A description of the protracted course of kingella monoarthritis is given as an illustration of the importance of accounting for the slow growth, low viable numbers, and fastidious culture...
Staessen, J., Bulpitt, C., Clement, D., De Leeuw, P., Fagard, R., Fletcher, A., ...
OBJECTIVE--To investigate the relation between mortality and treated systolic and diastolic blood pressures. DESIGN--Randomised double blind placebo controlled trial. Mortality in the two treatment...
Pekkanen, J., Nissinen, A., Puska, P., Punsar, S., Karvonen, M. J.
OBJECTIVE--To assess the efficacy of high serum cholesterol concentration, raised blood pressure, and smoking as predictors of coronary heart disease. DESIGN--Prospective cohort study of middle aged...
Huijbregts, P., Feskens, E., Räsänen, L., Fidanza, F., Nissinen, A., Menotti, A., ...
OBJECTIVE: To investigate the association of dietary pattern and mortality in international data. DESIGN: Cohort study with 20 years' follow up of mortality. SETTING: Five cohorts in Finland, the...
A voxel based morphometry study on mild cognitive impairment
Pennanen, C, Testa, C, Laakso, M, Hallikainen, M, Helkala, E, Hanninen, T, ...
Background: Mild cognitive impairment (MCI) is the most widely used concept in classifying cognitive impairment in the elderly who do not fulfil the criteria for dementia. MCI is considered to confer...
Tabak, C., Smit, H., Rasanen, L., Fidanza, F., Menotti, A., Nissinen, A., ...
BACKGROUND—Results of epidemiological studies relating individual dietary factors to chronic obstructive pulmonary disease (COPD) are inconsistent. To evaluate the cross sectional association of...
Pulmonary function, smoking cessation and 30 year mortality in middle aged Finnish men
Pelkonen, M., Tukiainen, H., Tervahauta, M., Notkola, I., Kivela, S., Salorinne, Y., ...
BACKGROUND—Although it is well known that impaired pulmonary function is a strong predictor of mortality and that smoking decreases pulmonary function, little is known about the long term effect of...
Pelkonen, M, Notkola, I, Tukiainen, H, Tervahauta, M, Tuomilehto, J, Nissinen, A
BACKGROUND—Permanent smoking cessation reduces loss of pulmonary function. Less is known in the long term about individuals who give up smoking temporarily or quitters with lower initial pulmonary...
Coffee consumption is correlated with serum cholesterol in middle-aged Finnish men and women.
Tuomilehto, J, Tanskanen, A, Pietinen, P, Aro, A, Salonen, J T, Happonen, P, ...
The association between coffee consumption and serum cholesterol was studied in a cross-sectional epidemiological study in Finland where the annual per capita consumption of coffee (13.0 kg) is the...
Menotti, A, Keys, A, Kromhout, D, Nissinen, A, Blackburn, H, Fidanza, F, ...
STUDY OBJECTIVE--The aims were (1) to compare all cause mortality in population samples of different cultures; and (2) to cross predict fatal event by risk functions involving risk factors usually...
Yu, Z., Nissinen, A., Vartiainen, E., Song, G., Guo, Z., Tian, H.
STUDY OBJECTIVE—To analyse trends in socioeconomic differences in cardiovascular disease risk factors among an urban Chinese population using educational attainment as the socioeconomic...
Physical functioning in elderly Europeans: 10 year changes in the north and south: the HALE project
Aijanseppa, S., Notkola, I., Tijhuis, M., Van Staveren, W., Kromhout, D., Nissinen, A.
Objectives: To examine age related changes in physical functioning in elderly men and women.
Social class, health behaviour, and mortality among men and women in eastern Finland.
Pekkanen, J., Tuomilehto, J., Uutela, A., Vartiainen, E., Nissinen, A.
OBJECTIVE--To evaluate the associations between social class as defined by occupation, health behaviour, and mortality from all causes and coronary heart disease among middle aged men and women in...
Nissinen, A., Parikka-Alhola, K., Rita, H.
Green Public Procurement (GPP) has been considered as an important policy instrument in the context of sustainable consumption and production. The state and progress of GPP has earlier been measured...
Changes in premature deaths in Finland: successful long-term prevention of cardiovascular diseases.
Puska, P., Vartiainen, E., Tuomilehto, J., Salomaa, V., Nissinen, A.
This article describes the long-term consequences of successful cardiovascular disease (CVD) prevention and its influence on premature mortality in Finland, with special reference to North Karelia....
Berrios, X., Koponen, T., Huiguang, T., Khaltaev, N., Puska, P., Nissinen, A.
The Inter-Health Programme was launched in 1986 by WHO, with the collaboration of a coordination centre (National Public Health Institute, Finland) to control and prevent chronic noncommunicable...
Ambrosio, G. B., Strasser, T., Dowd, J. E., Tuomilehto, J., Nissinen, A., Froment, A., ...
A WHO-coordinated study of the community control of hypertension in six countries (Cuba, Finland, France, Italy, Mongolia and Portugal) has shown that a comprehensive approach clearly improves the...
Yu, Z., Nissinen, A., Vartiainen, E., Song, G., Guo, Z., Zheng, G., ...
INTRODUCTION: In developed countries socioeconomic status has been proven to be an important factor in the progression of cardiovascular disease. The present article reports the results of a...
Nissinen, A., Berrios, X., Puska, P.
Community-based programmes for prevention and control of cardiovascular diseases (CVD) started in Europe and the USA in the early 1970s. High mortality from CVD in Finland led to the start of the...