A. Roth

Details der Publikationsliste

Zeitraum

1976 - 2009

Anzahl

198

Co-Autoren

Multicenter phase II trial of preoperative induction chemotherapy followed by chemoradiation with docetaxel and cisplatin for locally advanced esophageal carcinoma (SAKK 75/02) (2009)

Ruhstaller, T., Widmer, L., Schuller, J. C., Roth, A., Hess, V., Mingrone, W., ...

Background: This multicenter phase II study investigated the efficacy and feasibility of preoperative induction chemotherapy followed by chemoradiation and surgery in patients with esophageal...

Incidence and prognosis of non-Q-wave vs. Q-wave myocardial infarction following catheter-based reperfusion therapy (2009)

Halkin, A., Fourey, D., Roth, A., Boyko, V., Behar, S.

Background: The clinical importance of classifying myocardial infarction (MI) into non-Q-wave (NQWMI) vs. Q-wave (QWMI) subsets is controversial and might depend on the therapeutic reperfusion...

Ballistic Intrinsic Spin-Hall Effect in HgTe Nanostructures (2008)

Bruene, C., Roth, A., Novik, E. G., Koenig, M., Buhmann, H., Hankiewicz, E. M., ...

We report the first electrical manipulation and detection of the mesoscopic intrinsic spin-Hall effect (ISHE) in semiconductors through non-local electrical measurement in nano-scale H-shaped...

TERRASAR-X: HOW CAN HIGH RESOLUTION SAR DATA SUPPORT THE OBSERVATION OF URBAN AREAS? (2008)

A. Roth, J. Hoffmann, T. Esch

TerraSAR-X is a new German radar satellite that shall be launched in mid 2006. The expected lifetime is 5 years. It carries a high frequency X-band Synthetic Aperture Radar (SAR) sensor that can be...

A conceptual vulnerability and risk framework as outline to identify capabilities of remote sensing (2008)

Taubenböck, H., Post, J., Roth, A., Zosseder, K., Strunz, G., Dech, S.

This study aims at creating a holistic conceptual approach systematizing the interrelation of (natural) hazards, vulnerability and risk. A general hierarchical risk meta-framework presents...

A conceptual vulnerability and risk framework as outline to identify capabilities of remote sensing (2008)

Taubenböck, H., Post, J., Roth, A., Zosseder, K., Strunz, G., Dech, S.

This study aims at creating a holistic conceptual approach systematizing the interrelation of (natural) hazards, vulnerability and risk. A general hierarchical risk meta-framework presents...

Biol Cybern DOI 10.1007/s00422-008-0274-5 EDITORIAL Special issue on quantitative neuron modeling (2008)

Renaud Jolivet, Arnd Roth, Felix Schürmann, Wulfram Gerstner, Walter Senn, R. Jolivet (b, ...

Single neurons are the fundamental constituents of all nervous systems. Understanding the properties and dynamics of single neurons is therefore one of the key challenges in modern neuroscience....

A conceptual vulnerability and risk framework as outline to identify capabilities of remote sensing (2008)

H. Taubenböck, J. Post, A. Roth, K. Zosseder, G. Strunz, S. Dech

This study aims at creating a holistic conceptual approach systematizing the interrelation of (natural) hazards, vulnerability and risk. A general hierarchical risk meta-framework presents...

Adding cetuximab to capecitabine plus oxaliplatin (XELOX) in first-line treatment of metastatic colorectal cancer: a randomized phase II trial of the Swiss Group for Clinical Cancer Research SAKK (2008)

Borner, M., Koeberle, D., Von Moos, R., Saletti, P., Rauch, D., Hess, V., ...

Background: To determine the activity and tolerability of adding cetuximab to the oxaliplatin and capecitabine (XELOX) combination in first-line treatment of metastatic colorectal cancer (MCC)....

Hydrogen storage based on complex metal hydrides. (2008)

Fichtner, M., Hu, J., Leon, A., Leng, H., Lohstroh, W., Roth, A., ...

Materials for Hydrogen : Nanostructured Interfaces and Surfaces (NIS) Centre of Excellence Kolloquium, Torino, I, November 27-29, 2008

German Remote Sensing Data Center (DFD) (2007)

D. Kosmann, M. Bollner, A. Roth, A. Benjes

for ENVISAT on behalf of ESA and will be one of the nominated ASAR processing and archiving centers. In addition to its role on behalf of ESA the DFD will provide a wide range of products generated...

The management of pancreatic cancer. Current expert opinion and recommendations derived from the 8th World Congress on Gastrointestinal Cancer, Barcelona, 2006 (2007)

Verslype, C, Van Cutsem, E, Dicato, M, Cascinu, S, Cunningham, D, Diaz-Rubio, E, ...

This article summarizes the expert discussion on the management of pancreatic cancer, which took place during the 8th World Congress on Gastrointestinal Cancer in June 2006 in Barcelona. A...

Micromagnetic coercivity distributions and interactions in chondrules with implications for paleointensities of the early solar system (2007)

Acton, G, Yin, Qingzhu Z, Verosub, K L, Jovane, L, Roth, A, Jacobsen, B, ...

[1] Chondrules in chondritic meteorites record the earliest stages of formation of the solar system, potentially providing information about the magnitude of early magnetic fields and early physical...

Sulfonylureas and glinides exhibit peroxisome proliferator-activated receptor gamma activity: A combined virtual screening and biological assay approach (2007)

Scarsi, M., Podvinec, M., Roth, A., Hug, H., Kersten, S., Albrecht, H., ...

Most drugs currently employed in the treatment of type 2 diabetes either target the sulfonylurea receptor stimulating insulin release (sulfonylureas, glinides), or target the peroxisome...

Dendrite-to-Soma Input/Output Function of Continuous Time-Varying Signals in Hippocampal CA1 Pyramidal Neurons (2007)

Erik P. Cook, Jennifer A. Guest, Yong Liang, Nicolas Y. Masse, Costa M, P. J. Sjostrom, ...

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[Abstract]   [Full Text]   [PDF] Local and Global Effects of Ih Distribution in Dendrites of Mammalian Neurons (2007)

Thomas Berger, Matthew E. Larkum, Hans-r. Lüscher, J Neurophysiol, P. J. Sjostrom, E. A. Rancz, ...

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Downloaded fro... (2007)

Physiol Rev, P. J. Sjostrom, E. A. Rancz, A. Roth, M. Hausser, Physiol Rev, ...

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Veterinary Science.. Synaptic Plasticity (2006)

Nace L. Golding, William L. Kath, Nelson Spruston, J Neurophysiol, P. J. Sjostrom, E. A. Rancz, ...

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Optimisation of irinotecan dose in the treatment of patients with metastatic colorectal cancer after 5-FU failure: results from a multinational, randomised phase II study (2005)

Dirix, L, Van Laethem, J-L, Borner, M, Gonzalez Baron, M, ...

Although irinotecan 350 mg m(-2) is a standard option for relapsed/refractory advanced colorectal cancer, there is some evidence that suggests that a higher dose may be more effective, with...

Experimental and numerical analysis of hollow and foam-filled A-stringer/A-former under axial compression load and bending moment (2005)

Krämer, R., Roth, A.

The topic of this investigation deals with experimental and numerical analysis of different configurations of hollow and of PMI foam-filled A-stringers/A-formers under axial compression load and...

SRTM mission-cross comparison of X adn C band data properties (2004)

Rosen, P., Eineder, M., Rabus, B., Gurrola, E., Hensley, S., Knopfle, W., ...

This paper compares the specific properties of the X and C band data sets with respect to global coverage, height accuracy, sensor specific errors, product definition, product format and availability.

The evolution of drug-activated nuclear receptors: one ancestral gene diverged into two xenosensor genes in mammals. (2004)

Handschin, C, Blättler, S, Roth, A, Looser, R, Oscarson, M, Kaufmann, M R, ...

BACKGROUND: Drugs and other xenobiotics alter gene expression of cytochromes P450 (CYP) by activating the pregnane X receptor (PXR) and constitutive androstane receptor (CAR) in mammals. In...

Geocoding of TerraSAR-X Data (2004)

A. Roth, M. Huber, D. Kosmann

TerraSAR-X is a new German radar satellite that shall be launched in April 2006. The expected lifetime is 5 years. It carries a high frequency X-band SAR sensor that can be operated in different...

developed by: W. Ahrendt, T. Baar, B. Beckert, R. Bubel, M. Giese, R. Hahnle, W. Menzel, W. Mostowski, A. Roth, S. Schlager, P.H. Schmitt, and others (2004)

Information Security Eth, W. Ahrendt, T. Baar, B. Beckert, R. Bubel, M. Giese, ...

specification of standard data structures (e.g. lists, sets) are stepwise refined to a concrete implementation. Security: access control (PAM authentication with iButton) Analysis of the state...

The Situation Today (2004)

W. Ahrendt, T. Baar, B. Beckert, R. Bubel, M. Giese, R. Hähnle, ...

safety critical applications, e.g. flight or railway control. security critical applications, e.g. access control. financial reasons (e.g. warranty), e.g. embedded devices. legal reasons, e.g....

Direct determination of the complete set of iron normal modes in a porphyrin-imidazole model for carbonmonoxy-heme proteins: [Fe(TPP)(CO)(1-Melm)] (2003)

Rai, B. K., Durbin, S. M., Prohofsky, E. W., Sage, J. T., Ellison, M. K., Roth, A., ...

Detailed Fe vibrational spectra have been obtained for the heme model complex [Fe(TPP)(CO)-(1-Melm)] using a new, highly selective and quantitative technique, Nuclear Resonance Vibrational...

Equalization of synaptic efficacy by activity- and timing-dependent synaptic plasticity (2003)

C. C. Rumsey, I. Rabinowitch, I. Rabinowitch, I. Segev, I. Segev, A. Roth, ...

You might find this additional information useful... This article cites 34 articles, 15 of which you can access free at:

Adjuvant treatment of colorectal cancer (current expert opinion derived from the Third International Conference: Perspectives in Colorectal Cancer, Dublin, 2001) (2002)

Dicato, M, Wils, J, Cunningham, D, Diaz-Rubio, E, Glimelius, B, ...

This article summarises the progress that has been made in the adjuvant treatment of colorectal cancer over the last decade. In view of the consequent improvements in recurrence rates and in overall...

Purification and characterization of the recombinant Na+-translocating NADH : quinone oxidoreductase from vibrio cholerae (2002)

Barquera, B., Hellwig, P., Zhou, W. D., Morgan, J. E., Häse, C. C., Gosink, K. K., ...

The nqr operon from Vibrio cholerae, encoding the entire six-subunit, membrane-associated, Na+-translocating NADH:quinone oxidoreductase (Na+-NQR), was cloned under the regulation of the P-BAD...

Structure of methylene-tetrahydromethanopterin dehydrogenase from Methylobacterium extorquens AM1 (2002)

Ermler, U., Hagemeier, C. H., Roth, A., Demmer, U., Grabarse, W., Warkentin, E., ...

NADP-dependent methylene-H4MPT dehydrogenase, MtdA, from Methylobacterium extorquens AM1 catalyzes the dehydrogenation of methylene-tetrahydro-methanopterin and methylene-tetrahydrofolate with...

Structure of adenylylsulfate reductase from the hyperthermophilic Archaeoglobus fulgidus at 1.6-Å resolution (2002)

Fritz, G., Roth, A., Schiffer, A., Buchert, T., Bourenkov, G., Bartunik, H. D., ...

The iron-sulfur flavoenzyme adenylylsulfate (adenosine 5'-phosphosulfate, APS) reductase catalyzes reversibly the reduction of APS to sulfite and AMP. The structures of APS reductase from the...

Crystal structures and enzymatic properties of three formyltransferases from archaea : Environmental adaptation and evolutionary relationship (2002)

Mamat, B., Roth, A., Grimm, C., Ermler, U., Tziatzios, C., Schubert, D., ...

Formyltransferase catalyzes the reversible formation of formylmethanofuran from N-5-formyltetrahydromethanopterin and methanofuran, a reaction involved in the C1 metabolism of methanogenic and...

Propagation of action potentials in dendrites depends on dendritic morphology (2001)

Vetter, P., Roth, A., Häusser, M.

Action potential propagation links information processing in different regions of the dendritic tree. To examine the contribution of dendritic morphology to the efficacy of propagation, simulations...

Speculative multithreaded processors (2001)

Sohi, Gurindar Singh, Roth, A.

This material is presented to ensure timely dissemination of scholarly and technical work. Copyright and all rights therein are retained by authors or by other copyright holders. All persons copying...

Medical history of hypercholesterolaemia adversely affects the outcome of out-of-hospital cardiopulmonary resuscitation. The 'Shahal' experience in Israel (2000)

Roth, A, Golovner, M, Gavish, D, Shapira, I, Malov, N, Sender, J, ...

Aims To evaluate the impact selected risk factors for cardiac death may have on the success rate in a large cohort of subscribers to ‘SHAHAL’ who were resuscitated from out-of-hospital cardiac...

SIBERIA - 1st Progress Report (1999)

Wagner, W., Schmullius, C., Balzter, H., Davidson, M., Gaveau, D., Gluck, M., ...

This report describes the porgress made and the problems encountered in the first six months of the SIBERIA project. The limited data availability has hampered methodological development and has...

SIBERIA - 2nd Progress Report (1999)

Wagner, W., Schmullius, C., Balzter, H., Davidson, M., Gaveau, D., Gluck, M., ...

This report describes the work done during the second six month period of the SIBERIA project. With the increasing availability of ground truth information and ERS SAR imagery methodological...

Experimente zur Vorvermischungsphase (QUEOS). (1999)

Huber, R., Kirstahler, M., Kuhn, D., Meyer, L., Roth, A., Schwall, M., ...

Projekt Nukleare Sicherheitsforschung. Jahresbericht 1998.

Experimente zur Dispersion von Corium. (1999)

Hartnagel, M., Kirstahler, M., Meyer, L., Roth, A., Schwall, M., Wachter, E., ...

Projekt Nukleare Sicherheitsforschung. Jahresbericht 1998.

Stress Corrosion Crack Growth Behaviour of AlLi Alloy 8090 in NaCl-Solution With Li2CO3-Addition. (1998)

Roth, A., Kaesche, H.

This paper examines the stress corrosion crack (SCC) growth behavior of the aluminum-lithium alloy 8090-T6 by immersion tests in an NaCl-Li2CO3 solution. Free corrosion potential was found to shift...

Experimente zur Vorvermischungsphase (QUEOS). (1998)

Huber, R., Kirstahler, M., Kuhn, D., Meyer, L., Roth, A., Schwall, M., ...

Projekt Nukleare Sicherheitsforschung. Jahresbericht 1997.

Experimente zur Vorvermischungsphase (QUEOS). (1997)

Huber, R., Kirstahler, M., Kuhn, D., Meyer, L., Roth, A., Schwall, M., ...

Projekt Nukleare Sicherheitsforschung. Jahresbericht 1996.

lschaemic heart disease: High-dose intravenous magnesium attenuates complement consumption after acute myocardial infarction treated by streptokinase (1996)

Roth, A., Kornowski, R., Agmon, Y., Vardinon, N., Sheps, D., Graph, E., ...

Objective This study was designed to detect changes in complement levels following acute myocardial infarction and to test whether magnesium sulphate (MgSO4 administration interferes with the...

The impact of 'Shahal' (a new cardiac emergency service) on subscribers' requests for medical assistance: characteristics and distribution of calls (1995)

Roth, A, Herling, M, Vishlitzki, V

The objectives of this study were to assess the impact of the new 'Shahal' (pre-hospital cardiac service) on subscribers' 'decision time'. A professional 24-h mobile emergency cardiac service has...

Effect of magnesium on restenosis after percutaneous transluminal coronary angioplasty: a clinical and angiographic evaluation in a randomized patient population: A pilot study (1994)

ROTH, A., ESHCHAR, Y., KEREN, G., KERBEL, S., HARSAT, A., VILLA, Y., ...

Restenosis is a major clinical problem following successful percutaneous transluminal coronary angioplasty. Since magnesium has vasodilator and antithrombotic effects, this study was designed to...

Organization of highly repetitive satellite DNA of two Cucurbitaceae species (Cucumis melo and Cucumis sativus) (1982)

Hemleben, V., Leweke, B., Roth, A., Stadler, J.

The prominent satellites of the Cucurbitaceae Cucumis melo (melon) and Cucumis sativus (cucumber) have been characterized. In actinomycin/CsC1 gradients where the satellite sequences can be separated...

Thermo- und fluiddynamische Versuche in Gas. (1976)

Marek, J., Mensinger, E., Rehme, K., Roth, A.

In: Projekt Schneller Brueter. 4.Vierteljahresbericht 1975.

Isolation of Nocardia paucivorans from the Cerebrospinal Fluid of a Patient with Relapse of Cerebral Nocardiosis

Eisenblätter, M., Disko, U., Stoltenburg-Didinger, G., Scherübl, H., Schaal, K. P., Roth, A., ...

Nocardia paucivorans represents a new species of the genus Nocardia that has recently been isolated from bronchial secretions of a patient with chronic lung disease. Here, we report on the course of...

SOS induction in Escherichia coli by infection with mutant filamentous phage that are defective in initiation of complementary-strand DNA synthesis.

Higashitani, N, Higashitani, A, Roth, A, Horiuchi, K

We report that the SOS response is induced in Escherichia coli by infection with mutant filamentous phage that are defective in initiation of the complementary (minus)-strand synthesis. One such...

Value of PCR for evaluating occurrence of parasitemia in immunocompromised patients with cerebral and extracerebral toxoplasmosis.

Roth, A, Roth, B, Arasteh, K N, Janitschke, K

PCR was used to evaluate the occurrence of Toxoplasma gondii parasitemia by detection of the B1 gene in blood samples in two groups of immunosuppressed patients (148 subjects) suspected of having...

Organization of highly repetitive satellite DNA of two Cucurbitaceae species (Cucumis melo and Cucumis sativus).

Hemleben, V, Leweke, B, Roth, A, Stadler, J

The prominent satellites of the Cucurbitaceae Cucumis melo (melon) and Cucumis sativus (cucumber) have been characterized, in actinomycin/CsCl gradients where the satellite sequences can be separated...

The FIS protein binds and bends the origin of chromosomal DNA replication, oriC, of Escherichia coli.

Gille, H, Egan, J B, Roth, A, Messer, W

The FIS protein (factor for inversion stimulation) is known to stimulate site-specific recombination processes, such as the inversion of the G segment of bacteriophage Mu, by binding to specific...

The DNA binding domain of the initiator protein DnaA.

Roth, A, Messer, W

The 94 C-terminal amino acids of the initiator protein DnaA of Escherichia coli are required and sufficient for specific binding to the cognate DNA binding site. The binding domain contains two...

Evolutionary attempts at 4 eyes in vertebrates.

Schwab, I R, Ho, V, Roth, A, Blankenship, T N, Fitzgerald, P G

PURPOSE: To understand and compare the optical, histological, and ecological differences among 4 vertebrate species that have had evolutionary attempts toward 4 eyes. METHODS: An evolutionary attempt...

Physiology and anatomy of synaptic connections between thick tufted pyramidal neurones in the developing rat neocortex.

Markram, H, Lübke, J, Frotscher, M, Roth, A, Sakmann, B

1. Dual voltage recordings were made from pairs of adjacent, synaptically connected thick tufted layer 5 pyramidal neurones in brain slices of young rat (14-16 days) somatosensory cortex to examine...

Dendritic and somatic glutamate receptor channels in rat cerebellar Purkinje cells.

Häusser, M, Roth, A

1. The properties of glutamate receptor (GluR) channels in outside-out patches from the dendrites and somata of rat cerebellar Purkinje cells in brain slice were studied using fast agonist...

Characteristics of respondents and non-respondents to a mailed questionnaire.

Barton, J, Bain, C, Hennekens, C H, Rosner, B, Belanger, C, Roth, A, ...

In establishing a cohort of U.S. nurses, an assessment of response bias was made comparing respondents and non-respondents with regard to age, education, state of residence, employment status, field...

Isolation of Nocardia paucivorans from the Cerebrospinal Fluid of a Patient with Relapse of Cerebral Nocardiosis

Eisenblätter, M., Disko, U., Stoltenburg-Didinger, G., Scherübl, H., Schaal, K. P., Roth, A., ...

Nocardia paucivorans represents a new species of the genus Nocardia that has recently been isolated from bronchial secretions of a patient with chronic lung disease. Here, we report on the course of...

SOS induction in Escherichia coli by infection with mutant filamentous phage that are defective in initiation of complementary-strand DNA synthesis.

Higashitani, N, Higashitani, A, Roth, A, Horiuchi, K

We report that the SOS response is induced in Escherichia coli by infection with mutant filamentous phage that are defective in initiation of the complementary (minus)-strand synthesis. One such...

Value of PCR for evaluating occurrence of parasitemia in immunocompromised patients with cerebral and extracerebral toxoplasmosis.

Roth, A, Roth, B, Arasteh, K N, Janitschke, K

PCR was used to evaluate the occurrence of Toxoplasma gondii parasitemia by detection of the B1 gene in blood samples in two groups of immunosuppressed patients (148 subjects) suspected of having...

Organization of highly repetitive satellite DNA of two Cucurbitaceae species (Cucumis melo and Cucumis sativus).

Hemleben, V, Leweke, B, Roth, A, Stadler, J

The prominent satellites of the Cucurbitaceae Cucumis melo (melon) and Cucumis sativus (cucumber) have been characterized, in actinomycin/CsCl gradients where the satellite sequences can be separated...

The FIS protein binds and bends the origin of chromosomal DNA replication, oriC, of Escherichia coli.

Gille, H, Egan, J B, Roth, A, Messer, W

The FIS protein (factor for inversion stimulation) is known to stimulate site-specific recombination processes, such as the inversion of the G segment of bacteriophage Mu, by binding to specific...

The DNA binding domain of the initiator protein DnaA.

Roth, A, Messer, W

The 94 C-terminal amino acids of the initiator protein DnaA of Escherichia coli are required and sufficient for specific binding to the cognate DNA binding site. The binding domain contains two...

Physiology and anatomy of synaptic connections between thick tufted pyramidal neurones in the developing rat neocortex.

Markram, H, Lübke, J, Frotscher, M, Roth, A, Sakmann, B

1. Dual voltage recordings were made from pairs of adjacent, synaptically connected thick tufted layer 5 pyramidal neurones in brain slices of young rat (14-16 days) somatosensory cortex to examine...

Dendritic and somatic glutamate receptor channels in rat cerebellar Purkinje cells.

Häusser, M, Roth, A

1. The properties of glutamate receptor (GluR) channels in outside-out patches from the dendrites and somata of rat cerebellar Purkinje cells in brain slice were studied using fast agonist...

Evolutionary attempts at 4 eyes in vertebrates.

Schwab, I R, Ho, V, Roth, A, Blankenship, T N, Fitzgerald, P G

PURPOSE: To understand and compare the optical, histological, and ecological differences among 4 vertebrate species that have had evolutionary attempts toward 4 eyes. METHODS: An evolutionary attempt...

Characteristics of respondents and non-respondents to a mailed questionnaire.

Barton, J, Bain, C, Hennekens, C H, Rosner, B, Belanger, C, Roth, A, ...

In establishing a cohort of U.S. nurses, an assessment of response bias was made comparing respondents and non-respondents with regard to age, education, state of residence, employment status, field...

Rapid resolution of ST elevation and prediction of clinical outcome in patients undergoing thrombolysis with alteplase (recombinant tissue-type plasminogen activator): results of the Israeli Study of Early Intervention in Myocardial Infarction.

Barbash, G I, Roth, A, Hod, H, Miller, H I, Rath, S, Har-Zahav, Y, ...

Alteplase (recombinant tissue-type plasminogen activator (rt-PA)) was infused within four hours of onset of symptoms in 286 patients with acute myocardial infarction. Delayed coronary angiography was...

Prevention of torsade de pointes in the congenital long QT syndrome: use of a pause prevention pacing algorithm

Viskin, S, Fish, R, Roth, A, Copperman, Y

Torsade de pointes in the congenital long QT syndrome (LQTS) is often pause dependent. Thus, the main goal of pacemaker treatment in the LQTS may be the prevention of pauses that facilitate the onset...

Macrophage specificity of three anti-CD68 monoclonal antibodies (KP1, EBM11, and PGM1) widely used for immunohistochemistry and flow cytometry

Kunisch, E, Fuhrmann, R, Roth, A, Winter, R, Lungershausen, W, Kinne, R

Objectives: To investigate the specificity of three anti-CD68 monoclonal antibodies (mAbs) for macrophages (Mφ) in immunohistochemistry (IHC) and flow cytometry (FACS).

IgE screening in 1701 newborn infants and the development of atopic disease during infancy.

Croner, S, Kjellman, N I, Eriksson, B, Roth, A

IgE screening was done using the Phadebas IgE PRIST technique on the cord blood of 1701 newborn infants. Of these 8.3% developed obvious or probable atopic disease, predominantly atopic dermatitis...

Optimisation of irinotecan dose in the treatment of patients with metastatic colorectal cancer after 5-FU failure: results from a multinational, randomised phase II study

Van Cutsem, E, Dirix, L, Van Laethem, J-L, Van Belle, S, Borner, M, Gonzalez Baron, M, ...

Although irinotecan 350 mg m−2 is a standard option for relapsed/refractory advanced colorectal cancer, there is some evidence that suggests that a higher dose may be more effective, with...

Induction of effective and antigen-specific antitumour immunity by a liposomal ErbB2/HER2 peptide-based vaccination construct

Roth, A, Rohrbach, F, Weth, R, Frisch, B, Schuber, F, Wels, W S

Efficient delivery of tumour-associated antigens to appropriate cellular compartments of antigen-presenting cells is of prime importance for the induction of potent, cell-mediated antitumour immune...