Abha Singh Bais, Steffen Grossmann, Martin Vingron
Vol. 23 ECCB 2006, pages e44–e49 doi:10.1093/bioinformatics/btl305
Simultaneous alignment and annotation of cis-regulatory regions (2007)
Bais, Abha Singh, Grossmann, Steffen, Vingron, Martin
Motivation: Current methods that annotate conserved transcription factor binding sites in an alignment of two regulatory regions perform the alignment and annotation step separately and combine the...
Simultaneous alignment and annotation of cis-regulatory regions. (2007)
Bais, Abha Singh, Grossmann, Steffen, Vingron, Martin
Motivation: Current methods that annotate conserved transcription factor binding sites in an alignment of two regulatory regions perform the alignment and annotation step separately and combine the...
Incorporating evolution of transcription factor binding sites into annotated alignments. (2007)
Bais, Abha Singh, Grossmann, Steffen, Vingron, Martin
Identifying transcription factor binding sites (TFBSs) is essential to elucidate putative regulatory mechanisms. A common strategy is to combine cross-species conservation with single sequence TFBS...
Elucidating the mechanisms of transcriptional regulation relies heavily on the sequence annotation of the binding sites of DNA-binding proteins called transcription factors. With the rationale that...