Maeda, Tadao, Cideciyan, Artur V., Maeda, Akiko, Golczak, Marcin, Aleman, Tomas S., Jacobson, Samuel G., ...
Inactivating mutations in the retinoid isomerase (RPE65) or lecithin:retinol acyltransferase (LRAT) genes cause Leber congenital amaurosis (LCA), a severe visual impairment in humans. Both enzymes...
Luka Voncina, Nadia Jemiai, Sherry Merkur, Christina Golna, Akiko Maeda, Shiyan Chao, ...
Bernd Rechel, European Observatory on Health Systems and Policies
Redundant and unique roles of retinol dehydrogenases in the mouse retina. (2007)
Maeda, Akiko, Maeda, Tadao, Sun, Wenyu, Zhang, Houbin, Baehr, Wolfgang, Palczewski, Krzysztof
Highly abundant short-chain alcohol dehydrogenases (RDHs) in the retina were assumed to be involved in the recycling of 11-cis-retinal chromophore in the visual cycle. Mutations in human RDH genes...
Nakagawa, Naoko, Kubota, Ritsuko, Maeda, Akiko, Nakagawa, Toshimasa, Okuno, Yoshinobu
Seventy-three B/Victoria group strains isolated in the 1996–1997 influenza season were divided into three groups according to the degree of reactivity to monoclonal antibody 8E6. Analysis of...
Ueda, Minoru, Maeda, Akiko, Nakagawa, Naoko, Kase, Tetsuo, Kubota, Ritsuko, Takakura, Hikaru, ...
We established a rapid method for the identification of influenza A and B virus strains: the peroxidase-antiperoxidase (PAP) staining method with two subtype-specific murine monoclonal antibodies,...
Nakagawa, Naoko, Kubota, Ritsuko, Maeda, Akiko, Okuno, Yoshinobu
In the 2002-2003 season, influenza B virus Victoria strains were epidemic after a 6-year absence in Kobe City, Japan. They reacted poorly to the immune ferret sera prepared for use against the...
Role of Photoreceptor-specific Retinol Dehydrogenase in the Retinoid Cycle in Vivo*
Maeda, Akiko, Maeda, Tadao, Imanishi, Yoshikazu, Kuksa, Vladimir, Alekseev, Andrei, Bronson, J. Darin, ...
The retinoid cycle is a recycling system that replenishes the 11-cis-retinal chromophore of rhodopsin and cone pigments. Photoreceptor-specific retinol dehydrogenase (prRDH) catalyzes reduction of...
Kim, Tom S., Maeda, Akiko, Maeda, Tadao, Heinlein, Cynthia, Kedishvili, Natalia, Palczewski, Krzysztof, ...
The oxidation of 11-cis-retinol to 11-cis-retinal in the retinal pigment epithelium (RPE) represents the final step in a metabolic cycle that culminates in visual pigment regeneration. Retinol...
Maeda, Akiko, Crabb, John W., Palczewski, Krzysztof
High oxygen tension, exposure to light, and the biochemical events of vision generate significant oxidative stress in the retina and the retinal pigment epithelium (RPE). Understanding the mechanisms...
Rhodopsin Signaling and Organization in Heterozygote Rhodopsin Knockout Mice*S
Liang, Yan, Fotiadis, Dimitrios, Maeda, Tadao, Maeda, Akiko, Modzelewska, Anna, Filipek, Slawomir, ...
Rhodopsin (Rho) resides within internal membrane structures called disc membranes that are found in the rod outer segments (ROS) of photoreceptors in the retina. Rho expression is essential for...
Haeseleer, Françoise, Imanishi, Yoshikazu, Maeda, Tadao, Possin, Daniel E, Maeda, Akiko, Lee, Amy, ...
CaBP1–8 are neuronal Ca2+-binding proteins with similarity to calmodulin (CaM). Here we show that CaBP4 is specifically expressed in photoreceptors, where it is localized to synaptic terminals. The...
Nakagawa, Naoko, Kubota, Ritsuko, Maeda, Akiko, Nakagawa, Toshimasa, Okuno, Yoshinobu
Seventy-three B/Victoria group strains isolated in the 1996–1997 influenza season were divided into three groups according to the degree of reactivity to monoclonal antibody 8E6. Analysis of...
Ueda, Minoru, Maeda, Akiko, Nakagawa, Naoko, Kase, Tetsuo, Kubota, Ritsuko, Takakura, Hikaru, ...
We established a rapid method for the identification of influenza A and B virus strains: the peroxidase-antiperoxidase (PAP) staining method with two subtype-specific murine monoclonal antibodies,...
Nakagawa, Naoko, Kubota, Ritsuko, Maeda, Akiko, Okuno, Yoshinobu
In the 2002-2003 season, influenza B virus Victoria strains were epidemic after a 6-year absence in Kobe City, Japan. They reacted poorly to the immune ferret sera prepared for use against the...
Redundant and unique roles of retinol dehydrogenases in the mouse retina
Maeda, Akiko, Maeda, Tadao, Sun, Wenyu, Zhang, Houbin, Baehr, Wolfgang, Palczewski, Krzysztof
Highly abundant short-chain alcohol dehydrogenases (RDHs) in the retina were assumed to be involved in the recycling of 11-cis-retinal chromophore in the visual cycle. Mutations in human RDH genes...
Golczak, Marcin, Maeda, Akiko, Bereta, Grzegorz, Maeda, Tadao, Kiser, Philip D., Hunzelmann, Silke, ...
In vertebrate retinal photoreceptors, the absorption of light by rhodopsin leads to photoisomerization of 11-cis-retinal to its all-trans isomer. To sustain vision, a metabolic system evolved that...
Retinyl Ester Homeostasis in the Adipose Differentiation-related Protein-deficient Retina*S⃞
Imanishi, Yoshikazu, Sun, Wenyu, Maeda, Tadao, Maeda, Akiko, Palczewski, Krzysztof
The retinal pigmented epithelium (RPE) plays an essential role in vision, including storing and converting retinyl esters of the visual chromophore, 11-cis-retinal. Retinyl ester storage structures...
Retinopathy in Mice Induced by Disrupted All-trans-retinal Clearance*S⃞
Maeda, Akiko, Maeda, Tadao, Golczak, Marcin, Palczewski, Krzysztof
The visual (retinoid) cycle is a fundamental metabolic process in vertebrate retina responsible for production of 11-cis-retinal, the chromophore of rhodopsin and cone pigments. 11-cis-Retinal is...