Andreas Waha

MethMarker: user-friendly design and optimization of gene-specific DNA methylation assays (2009)

Schüffler, Peter, Mikeska, Thomas, Waha, Andreas, Lengauer, Thomas, Bock, Christoph

Abstract DNA methylation is a key mechanism of epigenetic regulation that is frequently altered in diseases such as cancer. To confirm the biological or clinical relevance of such changes,...

Comparison of automated silver enhanced in situ hybridization and fluorescence in situ hybridization for evaluation of epidermal growth factor receptor status in human glioblastomas (2009)

Timo Gaiser, Andreas Waha, Franziska Moessler, Thomas Bruckner, Torsten Pietsch, Andreas Von Deimling

A systematic search for DNA methyltransferase polymorphisms reveals a rare DNMT3L variant associated with subtelomeric hypomethylation (2009)

El-Maarri, Osman, Kareta, Michael S., Mikeska, Thomas, Becker, Tim, Diaz-Lacava, Amalia, Junen, Judith, ...

Causes underlying inter-individual variations in DNA methylation profiles among normal healthy populations are not thoroughly understood. To investigate the contribution of genetic variation in DNA...

Optimization of Quantitative MGMT Promoter Methylation Analysis Using Pyrosequencing and Combined Bisulfite Restriction Analysis (2007)

Mikeska, Thomas, Bock, Christoph, El-Maarri, Osman, Hübner, Anika, Ehrentraut, Denise, Schramm, Johannes, ...

Analyse der Expression von Onkogenen und Tumorsuppressorgenen in Gliomen / (1997)

Waha, Andreas.

Bonn, Univ., Diss., 1998 (Nicht für den Austausch).

Epigenetic Silencing of the Protocadherin Family Member PCDH-γ-A11 in Astrocytomas1

Waha, Anke, Güntner, Stefanie, Huang, Tim Hui-Ming, Yan, Pearlly S, Arslan, Bülent, Pietsch, Torsten, ...

In a microarray-based methylation analysis of astrocytomas [World Health Organization (WHO) grade II], we identified a CpG island within the first exon of the protocadherin-γ subfamily A11...

Epigenetic Silencing of the Protocadherin Family Member PCDH-γ-A11 in Astrocytomas1

Waha, Anke, Güntner, Stefanie, Huang, Tim Hui-Ming, Yan, Pearlly S, Arslan, Bülent, Pietsch, Torsten, ...

In a microarray-based methylation analysis of astrocytomas [World Health Organization (WHO) grade II], we identified a CpG island within the first exon of the protocadherin-γ subfamily A11...

p57KIP2 Is Not Mutated in Hepatoblastoma but Shows Increased Transcriptional Activity in a Comparative Analysis of the Three Imprinted Genes p57KIP2, IGF2, and H19

Hartmann, Wolfgang, Waha, Andreas, Koch, Arend, Goodyer, Cynthia G., Albrecht, Steffen, Von Schweinitz, Dietrich, ...

Hepatoblastomas (HBs), representing malignant liver tumors of childhood, show frequent loss of heterozygosity (LOH) in the chromosomal region 11p15.5. This loss is of maternal origin suggesting the...

A Gammaherpesviral Internal Repeat Contributes to Latency Amplification

Thakur, Nagendra N., El-Gogo, Susanne, Steer, Beatrix, Freimüller, Klaus, Waha, Andreas, Adler, Heiko

Optimization of Quantitative MGMT Promoter Methylation Analysis Using Pyrosequencing and Combined Bisulfite Restriction Analysis

Mikeska, Thomas, Bock, Christoph, El-Maarri, Osman, Hübner, Anika, Ehrentraut, Denise, Schramm, Johannes, ...

Resistance to chemotherapy is a major complication during treatment of cancer patients. Hypermethylation of the MGMT gene alters DNA repair and is associated with longer survival of glioblastoma...

Aberrant Methylation and Reduced Expression of LHX9 in Malignant Gliomas of Childhood1

Vladimirova, Valentina, Mikeska, Thomas, Waha, Andreas, Soerensen, Niels, Xu, Jingying, Reynolds, Patrick C, ...

High-grade gliomas (HGGs) of childhood represent approximately 7% of pediatric brain tumors. They are highly invasive tumors and respond poorly to conventional treatments in contrast to pilocytic...

MethMarker: user-friendly design and optimization of gene-specific DNA methylation assays

Schüffler, Peter, Mikeska, Thomas, Waha, Andreas, Lengauer, Thomas, Bock, Christoph

A software workflow to translate known differentially methylated regions into clinical biomarkers