Andrew L. Hufton

Deeply conserved chordate noncoding sequences preserve genome synteny but do not drive gene duplicate retention (2009)

Hufton, Andrew L., Mathia, Susanne, Braun, Helene, Georgi, Udo, Lehrach, Hans, Vingron, Martin, ...

Animal genomes possess highly conserved cis-regulatory sequences that are often found near genes that regulate transcription and development. Researchers have proposed that the strong conservation of...

Early vertebrate whole genome duplications were predated by a period of intense genome rearrangement (2008)

Hufton, Andrew L., Groth, Detlef, Vingron, Martin, Lehrach, Hans, Poustka, Albert, Panopoulou, Georgia

Researchers, supported by data from polyploid plants, have suggested that whole genome duplication (WGD) may induce genomic instability and rearrangement, an idea which could have important...

Semaphorin and neuropilin expression during early morphogenesis of Xenopus laevis (2008)

Koestner, Ulrich, Shnitsar, Iryna, Linnemannstöns, Karen, Hufton, Andrew L., Borchers, Annette

Semaphorins are major regulators of morphogenesis and are involved in a variety of processes ranging from the guidance of cell migration to the development of cancer. Since semaphorins were first...

Early vertebrate whole genome duplications were predated by a period of intense genome rearrangement (2008)

Hufton, Andrew L., Groth, Detlef, Vingron, Martin, Lehrach, Hans, Poustka, Albert J., Panopoulou, Georgia

Researchers, supported by data from polyploid plants, have suggested that whole genome duplication (WGD) may induce genomic instability and rearrangement, an idea which could have important...

Early vertebrate whole genome duplications were predated by a period of intense genome rearrangement (2008)

Hufton, Andrew L., Groth, Detlef, Vingron, Martin, Lehrach, Hans, Poustka, Albert J., Panopoulou, Georgia

Researchers, supported by data from polyploid plants, have suggested that whole genome duplication (WGD) may induce genomic instability and rearrangement, an idea which could have important...

Genomic analysis of Xenopusorganizer function (2006)

Hufton, Andrew L, Vinayagam, Arunachalam, Suhai, Sándor, Baker, Julie C

Abstract Background Studies of the Xenopus organizer have laid the foundation for our understanding of the conserved signaling pathways that pattern vertebrate embryos during gastrulation. The two...

Early vertebrate whole genome duplications were predated by a period of intense genome rearrangement

Hufton, Andrew L., Groth, Detlef, Vingron, Martin, Lehrach, Hans, Poustka, Albert J., Panopoulou, Georgia

Researchers, supported by data from polyploid plants, have suggested that whole genome duplication (WGD) may induce genomic instability and rearrangement, an idea which could have important...