Takeuchi, Nobuto, Salazar, Laura, Poole, Anthony M, Hogeweg, Paulien
Abstract Background The simplest conceivable example of evolving systems is RNA molecules that can replicate themselves. Since replication produces a new RNA strand complementary to a template, all...
Freyhult, Eva, Edvardsson, Sverker, Tamas, Ivica, Moulton, Vincent, Poole, Anthony M
Abstract Background The H/ACA family of small nucleolar RNAs (snoRNAs) plays a central role in guiding the pseudouridylation of ribosomal RNA (rRNA). In an effort to systematically identify the...
Did group II intron proliferation in an endosymbiont-bearing archaeon create eukaryotes? (2006)
Abstract Martin & Koonin recently proposed that the eukaryote nucleus evolved as a quality control mechanism to prevent ribosome readthrough into introns. In their scenario, the bacterial ancestor of...
Nadja Neumann, Daniel C. Jeffares, Anthony M. Poole
The nuclear pore complex (NPC) facilitates transport between nucleus and cytoplasm. The protein constituents of the NPC, termed nucleoporins (Nups), are conserved across a wide diversity of...
Poole, Anthony M., Logan, Derek T.
RNA repair has now been demonstrated to be a genuine biological process, and appears to be present in all three domains of life. In this article, we consider what this might mean for the transition...
Poole, Anthony M., Logan, Derek T.
RNA repair has now been demonstrated to be a genuine biological process and appears to be present in all three domains of life. In this article, we consider what this might mean for the transition...
Poole, Anthony M., Logan, Derek T.
RNA repair has now been demonstrated to be a genuine biological process, and appears to be present in all three domains of life. In this article, we consider what this might mean for the transition...
A search for H/ACA snoRNAs in yeast using MFE secondary structure prediction (2003)
Edvardsson, Sverker, Gardner, Paul P., Poole, Anthony M., Hendy, Michael D., Penny, David, Moulton, Vincent
Motivation: Noncoding RNA genes produce functional RNA molecules rather than coding for proteins. One such family is the H/ACA snoRNAs. Unlike the related C/D snoRNAs these have resisted automated...
Did group II intron proliferation in an endosymbiont-bearing archaeon create eukaryotes?
Martin & Koonin recently proposed that the eukaryote nucleus evolved as a quality control mechanism to prevent ribosome readthrough into introns. In their scenario, the bacterial ancestor of...
Endosymbiont gene functions impaired and rescued by polymerase infidelity at poly(A) tracts
Tamas, Ivica, Wernegreen, Jennifer J., Nystedt, Björn, Kauppinen, Seth N., Darby, Alistair C., Gomez-Valero, Laura, ...
Among host-dependent bacteria that have evolved by extreme reductive genome evolution, long-term bacterial endosymbionts of insects have the smallest (160–790 kb) and most A + T-rich (>70%)...
Outsourcing the Nucleus: Nuclear Pore Complex Genes are no Longer Encoded in Nucleomorph Genomes
Neumann, Nadja, Jeffares, Daniel C., Poole, Anthony M.
The nuclear pore complex (NPC) facilitates transport between nucleus and cytoplasm. The protein constituents of the NPC, termed nucleoporins (Nups), are conserved across a wide diversity of...