Anthony P. Sinai

Trypanosoma cruzi Infection and Nuclear Factor Kappa B Activation Prevent Apoptosis in Cardiac Cells

Petersen, Christine A., Krumholz, Katherine A., Carmen, John, Sinai, Anthony P., Burleigh, Barbara A.

Studies of cardiac pathology and heart failure have implicated cardiomyocyte apoptosis as a critical determinant of disease. Recent evidence indicates that the intracellular protozoan parasite...

Trypanosoma cruzi Infection and Nuclear Factor Kappa B Activation Prevent Apoptosis in Cardiac Cells

Petersen, Christine A., Krumholz, Katherine A., Carmen, John, Sinai, Anthony P., Burleigh, Barbara A.

Studies of cardiac pathology and heart failure have implicated cardiomyocyte apoptosis as a critical determinant of disease. Recent evidence indicates that the intracellular protozoan parasite...

The Apicomplexan Pathogen Neospora caninum Inhibits Host Cell Apoptosis in the Absence of Discernible NF-κB Activation▿

Herman, Rebecca K., Molestina, Robert E., Sinai, Anthony P., Howe, Daniel K.

Neospora caninum, a causative agent of bovine abortions, is an apicomplexan parasite that is closely related to the human pathogen Toxoplasma gondii. Since a number of intracellular parasites,...

Toxoplasma gondii Exploits Host Low-Density Lipoprotein Receptor-Mediated Endocytosis for Cholesterol Acquisition

Coppens, Isabelle, Sinai, Anthony P., Joiner, Keith A.

The obligate intracellular protozoan Toxoplasma gondii resides within a specialized parasitophorous vacuole (PV), isolated from host vesicular traffic. In this study, the origin of parasite...

The Toxoplasma gondii protein ROP2 mediates host organelle association with the parasitophorous vacuole membrane

Sinai, Anthony P., Joiner, Keith A.

Toxoplasma gondii replicates within a specialized vacuole surrounded by the parasitophorous vacuole membrane (PVM). The PVM forms intimate interactions with host mitochondria and endoplasmic...