DELMAS, PD, PORNEL, B, FELSENBERG, D, GARNERO, P, HARDY, P, PILATE, C, ...
P53 mutations in human adrenocortical neoplasms (1994)
Reincke, Martin, Karl, M., Travis, W., Mastorakis, G., Allolio, B., Linehan, M., ...
The mechanisms of tumorigenesis of adrenocortical neoplasms have not been elucidated as yet. However, loss of heterozygosity at chromosomal locus 17p has been consistently observed in adrenocortical...
Suramin in adrenocortical cancer (1994)
Arlt, W., Reincke, Martin, Siekmann, L., Winkelmann, W., Allolio, B.
Clonal Composition of Human Adrenocortical Neoplasms (1994)
Beuschlein, Felix, Reincke, Martin, Karl, M., Travis, W., Chrousos, G. P., Jaursch-Hancke, C., ...
The mechanisms of tumorigenesis of adrenocortical neoplasms are still not understood. Tumor formation may be the result of spontaneous transformation of adrenocortical cells by somatic mutations....
Bilaterale massive makronoduläre Nebennierenhyperplasie (1994)
Strohm, M., Reincke, Martin, Theiß, M., Diehl, K. L., Allolio, B.
Bei einem 46jährigen Patienten bestand seit 10 Jahren eine arterielle Hypertonie. In den letzten beiden Jahren entwickelten sich eine stammbetonte Adipositas sowie weitere typische Stigmata eines...
The hypothalamic-pituitary-adrenal axis in critical illness (1993)
Reincke, Martin, Würth, G., Allolio, B., Winkelmann, W.
Plasma ACTH and cortisol concentrations are frequently elevated in patients in intensive care units (ICU). To examine the functional integrity of the hypothalamic-pituitary-adrenal axis during...
Thyroid dysfunction in African trypanosomiasis (1993)
Reincke, Martin, Allolio, B., Arlt, W., Heppner, C., Petzke, F., Mbulamberi, D., ...
Preclinical Cushing's syndrome in adrenal incidentalomas (1992)
Reincke, Martin, Nieke, J., Krestin, G. P., Saeger, W., Allolio, B., Winkelmann, W.
Adrenal tumors are usually diagnosed by clinical symptoms of hormone excess. The increasing use of ultrasound and computed tomography results in the detection of a substantial number of incidentally...
Langzeitbehandlung mit Pravidel bei Prolaktinompatienten (1991)
Winkelmann, W., Allolio, B., Deuß, U., Heesen, D., Nieke, J., Reincke, Martin
In Europa erworbene vizerale Leishmaniose (Kalar-Azar) (1990)
Reincke, Martin, Allolio, B., Hackenberg, E., Cohen, S., Winkelmann, W., Kaufmann, W.
The 'incidentaloma' of the pituitary gland. Is neurosurgery required? (1990)
Reincke, Martin, Allolio, B., Saeger, W., Menzel, J., Winkelmann, W.
We describe a series of 18 patients with an intrasellar mass incidentally discovered by computed tomography or magnetic resonance imaging. The average size of the mass was 13 mm, with a range from 5...
Management and efficacy of intensified insulin therapy starting in outpatients (1989)
Ollenschläger, G., Hummerich, W., Steffen, M., Reincke, Martin, Allolio, B., Winkelmann, W.
Diabetic patients under multiple injection insulin therapy (i.e., intensified insulin therapy, IIT) usually start this treatment during hospitalization. We report here on the logistics, efficacy, and...
Reincke, Martin, Allolio, B., Deuß, U., Winkelmann, W.
We investigated the molecular size of circulating immunoreactive ACTH by gel chromatography in patients with ACTH hypersecretion due to various disorders of the hypothalamic-pituitary-adrenal axis. 4...
Suramin for treatment of adrenocortical carcinoma (1989)
Allolio, B., Reincke, Martin, Arlt, W., Deuß, U., Winkelmann, W.
Behandlung des metastasierten Nebennierenkarzinoms mit Suramin (1989)
Allolio, B., Jaursch-Hancke, C., Reincke, Martin, Arlt, W., Metzler, U., Winkelmann, W.
Bei einem 45jährigen Patienten wurde im April 1986 ein rechtsseitiges Nebennierenrindenkarzinom (978 g) entfernt und das Tumorbett postoperativ mit 40 Gy bestrahlt. Wegen multipler Lungenmetastasen...
Diagnostik und Therapie asymptomatischer Nebennierentumoren (1989)
Reincke, Martin, Winkelmann, W., Jaursch-Hancke, C., Kaulen, D., Nieke, J., Ollenschläger, G., ...
Bei 23 Frauen und neun Männern im mittleren Alter von 54 (25-73) Jahren wurde bei der Klärung anderer Beschwerden zufällig ein asymptomatischer Nebennierentumor entdeckt. In allen Fällen ließen...
Diagnostische Probleme beim ektopen Cushing-Syndrom (1988)
Reincke, Martin, Allolio, B., Jaursch-Hancke, C., Kaulen, D., Saeger, W., Leonhard, U., ...
The effect of sodium valproate in Cushing's disease, Nelson's syndrome and Addison's disease (1988)
Reincke, Martin, Allolio, B., Kaulen, D., Jaursch-Hancke, C., Winkelmann, W.
We investigated the effect of sodium valproate on plasma ACTH and serum cortisol concentrations in different pathological states of ACTH hypersecretion. Five patients with pituitary dependent...
Allolio, B., Schulte, H. M., Kaulen, D., Reincke, Martin, Jaursch-Hancke, C., Winkelmann, W.
We determined the adrenostatic potential of low-dose nonhypnotic etomidate in six patients with Cushing's syndrome (ectopic Cushing's syndrome,n=2; Cushing's disease,n=3; bilateral adrenal...
Reincke, Martin, Allolio, B., Jaursch-Hancke, C., Kaulen, D., Winkelmann, W.
Bei zehn Patienten mit ACTH-abhängigem Cushing-Syndrom, vier mit ektopem Cushing-Syndrom und sechs mit M. Cushing, wurde retrospektiv die Wirksamkeit einer adrenostatischen Therapie mit Metyrapon...
Hodgkinson, S C, Allolio, B, Landon, J, Lowry, P J
The development of a 'two-site' immunoradiometric assay (i.r.m.a.) for the direct estimation of human corticotropin-(1-39)-peptide in plasma is described. The assay is based on the simultaneous...
Hodgkinson, S C, Allolio, B, Landon, J, Lowry, P J
The development of a 'two-site' immunoradiometric assay (i.r.m.a.) for the direct estimation of human corticotropin-(1-39)-peptide in plasma is described. The assay is based on the simultaneous...