Agonist-induced ADP-ribosylation of a cytosolic protein in human platelets.
Brüne, B, Molina Y Vedia, L, Lapetina, E G
alpha-Thrombin and phorbol 12,13-dibutyrate stimulated the mono(ADP-ribosyl)ation of a 42-kDa cytosolic protein of human platelets. This effect was mediated by protein kinase C activation and was...
Brüne, B, Von Appen, F, Ullrich, V
Fura-2-loaded human platelets were used to study Ca2+ release from intracellular compartments, as well as Ca2+ influx from the extracellular space. We investigated the response towards the...
Heat shock proteins and macrophage resistance to the toxic effects of nitric oxide.
Hirvonen, M R, Brüne, B, Lapetina, E G
Nitric oxide (NO) functions as a pathophysiological mediator in mammalian tissues. Activated macrophages produce NO as a non-specific immune response directed against invading bacteria or...
Nitric oxide-induced apoptosis: p53-dependent and p53-independent signalling pathways.
Nitric oxide (NO) generation initiates apoptotic cell death in different experimental systems. In RAW 264.7 macrophages the appearance of typical apoptotic markers is linked to inducible NO synthase...
Initiation of nitric oxide (NO.)-mediated apoptotic cell death in RAW 264.7 macrophages is associated with up-regulation of mitochondrial manganese superoxide dismutase (MnSOD; SOD2) and...
Agonist-induced ADP-ribosylation of a cytosolic protein in human platelets.
Brüne, B, Molina Y Vedia, L, Lapetina, E G
alpha-Thrombin and phorbol 12,13-dibutyrate stimulated the mono(ADP-ribosyl)ation of a 42-kDa cytosolic protein of human platelets. This effect was mediated by protein kinase C activation and was...
Brüne, B, Von Appen, F, Ullrich, V
Fura-2-loaded human platelets were used to study Ca2+ release from intracellular compartments, as well as Ca2+ influx from the extracellular space. We investigated the response towards the...
Heat shock proteins and macrophage resistance to the toxic effects of nitric oxide.
Hirvonen, M R, Brüne, B, Lapetina, E G
Nitric oxide (NO) functions as a pathophysiological mediator in mammalian tissues. Activated macrophages produce NO as a non-specific immune response directed against invading bacteria or...
Nitric oxide-induced apoptosis: p53-dependent and p53-independent signalling pathways.
Nitric oxide (NO) generation initiates apoptotic cell death in different experimental systems. In RAW 264.7 macrophages the appearance of typical apoptotic markers is linked to inducible NO synthase...
Initiation of nitric oxide (NO.)-mediated apoptotic cell death in RAW 264.7 macrophages is associated with up-regulation of mitochondrial manganese superoxide dismutase (MnSOD; SOD2) and...
Nitsch, D. D., Ghilardi, N., Mühl, H., Nitsch, C., Brüne, B., Pfeilschifter, J.
Nitric oxide (NO) is a multipurpose messenger molecule, important for blood vessel relaxation, neuronal communication, and antimicrobial activities. The generation of NO from L-arginine is catalyzed...