Dennis A. Smith, R. Scott Obach, T. A. Baillie, M. N. Cayen, H. Fouda, R. J. Gerson, ...
Recent attention has been given to the potential roles that metabolites could play in safety evaluations of new drugs. In 2002, a proposal was published on “metabolites in safety testing ”...
ALGON is an open C-macro package for developing Genetic Algorithms (GA). Besides a variety of classical GA operators and strategies, ALGON structures and genetic operators allow to handle non binary...
Inverse problems for finite automata: a solution based on Genetic Algorithms (2007)
The use of heuristics such as Genetic Algorithm optimisation methods is appealing in a large range of inverse problems. The problem presented here deals with the mathematical analysis of sequences...
Define “Validation Metric ” by What You Want to Do with It (2007)
D. P. Stotler, B. Leblanc, S. J. Zweben, R. J. Maqueda
• See [O&B 2006] for CFD perspective. • Quantitative approach to code calibration, • Determine where model & experiment agree well & where they don’t, – Know where to focus...
Leblanc, B., Lutton, E., Axel, F.
We present the first application of genetic algorithms to the analysis of data froma an aperiodically ordered system, high resolution X-ray diffraction spectra from multilayer heterostructures...
Leblanc, B., Lutton, E., Axel, F.
We present the first application of genetic algorithms to the analysis of data froma an aperiodically ordered system, high resolution X-ray diffraction spectra from multilayer heterostructures...
Leblanc, B., Lutton, E., Axel, F.
We present the first application of genetic algorithms to the analysis of data froma an aperiodically ordered system, high resolution X-ray diffraction spectra from multilayer heterostructures...
Leblanc, B., Lutton, E., Axel, F.
We present the first application of genetic algorithms to the analysis of data froma an aperiodically ordered system, high resolution X-ray diffraction spectra from multilayer heterostructures...
Overview of ASDEX Upgrade results (1997)
KAUFMANN, M, SCHWEINZER, J, ALBRECHT, M, ALEXANDER, M, Asmussen, Katrin, BECKER, G, ...
Rolston, K. V. I., Dholakia, N., Ho, D. H., LeBlanc, B., Dvorak, T., Streeter, H.
The in-vitro activities of ramoplanin, vancomycin, and teicoplanin against Gram-positive organisms isolated from cancer patients were determined. Ramoplanin was the most active agent tested...
Lyn Lewis, E., Ponton, Dominique, Legendre, L., Leblanc, B.
Sampling was conducted in the Northwater Polynya (between 70°20' and 77°20'N), on 17 and 19 May 1991. At each of the 14 sampling stations, CTD profiles were recorded from surface to bottom and...
The Pbx-M Thomson Scattering System (1990)
Leblanc, B., Bell, R., Dimock, D., Duperrex, P. A., Felt, J., Palladino, R.
In vitro activity of sparfloxacin (CI-978; AT-4140) against clinical isolates from cancer patients.
Rolston, K V, Nguyen, H, Messer, M, LeBlanc, B, Ho, D H, Bodey, G P
The in vitro activity of sparfloxacin, a new quinolone, was compared with those of ciprofloxacin and fleroxacin against gram-positive and gram-negative bacteria, greater than 90% of which were...
Rolston, K V, Ho, D H, LeBlanc, B, Bodey, G P
The in vitro activity of S-25930 and S-25932, two new 4-quinolones, against 450 aerobic gram-negative organisms isolated from cancer patients was evaluated and compared with the activity of...
Rolston, K V, LeBlanc, B, Ho, D H, Bodey, G P
The in vitro activity of paldimycin, a novel antimicrobial agent, was compared with that of vancomycin against 306 gram-positive isolates (representing 12 bacterial species) obtained from patients...
Garcia, I, Bodey, G P, Fainstein, V, Ho, D H, LeBlanc, B
The activity of WIN 49375 [6-fluoro-1, 4-dihydro-1-(methylamino)-7-(4-methyl-1-piperazinyl)-4-oxo-3- quinolinecarboxylic acid], a new synthetic quinolone, was tested in vitro against 587 clinical...
In vitro studies of BMY-28142, a new broad-spectrum cephalosporin.
Bodey, G P, Ho, D H, LeBlanc, B
BMY-28142 was compared with other broad-spectrum antibiotics against gram-positive cocci and gram-negative bacilli. BMY-28142 was highly active against all gram-negative bacilli and especially...
Comparative in vitro study of teichomycin A2.
Fainstein, V, LeBlanc, B, Bodey, G P
Teichomycin A2 was evaluated in vitro against clinical isolates, and its activity was compared with that of other antibiotics. This compound was very active against all organisms tested; its activity...
Comparative in vitro activities of teichomycin and other antibiotics against JK diphtheroids.
Jadeja, L, Fainstein, V, LeBlanc, B, Bodey, G P
The in vitro susceptibilities of 98 isolates of JK diphtheroids to teichomycin, vancomycin, and eight other antibiotics was investigated. Teichomycin and vancomycin were extremely active against all...
In vitro activities of new beta-lactam antibiotics against Acinetobacter spp.
Garcia, I, Fainstein, V, LeBlanc, B, Bodey, G P
The in vitro activities of new beta-lactam antibiotics was studied and compared with those of other known agents against 51 clinical isolates of Acinetobacter calcoaceticus subsp. anitratus and 23...
Rolston, K V, Nguyen, H T, Ho, D H, LeBlanc, B, Bodey, G P
The in vitro activity of Ro 23-9424 against bacterial isolates from patients with cancer was compared with those of fleroxacin, ciprofloxacin, cefoperazone, and ceftazidime. Ro 23-9424 inhibited the...
Rolston, K V, Ho, D H, LeBlanc, B, Bodey, G P
We evaluated the in vitro activities of 21 different antimicrobial agents against nine clinical isolates of Flavimonas oryzihabitans obtained from patients with cancer. The organisms were susceptible...
Dholakia, N, Rolston, K V, Ho, D H, LeBlanc, B, Bodey, G P
The antibacterial activity of levofloxacin was compared with those of ofloxacin and ciprofloxacin against bacterial isolates from patients with cancer. In general, levofloxacin was as active or was...
The interaction of the ribosomal transcription factor xUBF with the RNA polymerase I core promoter of Xenopus laevis has been studied both at the DNA and protein levels. It is shown that a single...
In vitro activity of sparfloxacin (CI-978; AT-4140) against clinical isolates from cancer patients.
Rolston, K V, Nguyen, H, Messer, M, LeBlanc, B, Ho, D H, Bodey, G P
The in vitro activity of sparfloxacin, a new quinolone, was compared with those of ciprofloxacin and fleroxacin against gram-positive and gram-negative bacteria, greater than 90% of which were...
Rolston, K V, Ho, D H, LeBlanc, B, Bodey, G P
The in vitro activity of S-25930 and S-25932, two new 4-quinolones, against 450 aerobic gram-negative organisms isolated from cancer patients was evaluated and compared with the activity of...
Rolston, K V, LeBlanc, B, Ho, D H, Bodey, G P
The in vitro activity of paldimycin, a novel antimicrobial agent, was compared with that of vancomycin against 306 gram-positive isolates (representing 12 bacterial species) obtained from patients...
Garcia, I, Bodey, G P, Fainstein, V, Ho, D H, LeBlanc, B
The activity of WIN 49375 [6-fluoro-1, 4-dihydro-1-(methylamino)-7-(4-methyl-1-piperazinyl)-4-oxo-3- quinolinecarboxylic acid], a new synthetic quinolone, was tested in vitro against 587 clinical...
In vitro studies of BMY-28142, a new broad-spectrum cephalosporin.
Bodey, G P, Ho, D H, LeBlanc, B
BMY-28142 was compared with other broad-spectrum antibiotics against gram-positive cocci and gram-negative bacilli. BMY-28142 was highly active against all gram-negative bacilli and especially...
Comparative in vitro study of teichomycin A2.
Fainstein, V, LeBlanc, B, Bodey, G P
Teichomycin A2 was evaluated in vitro against clinical isolates, and its activity was compared with that of other antibiotics. This compound was very active against all organisms tested; its activity...
Comparative in vitro activities of teichomycin and other antibiotics against JK diphtheroids.
Jadeja, L, Fainstein, V, LeBlanc, B, Bodey, G P
The in vitro susceptibilities of 98 isolates of JK diphtheroids to teichomycin, vancomycin, and eight other antibiotics was investigated. Teichomycin and vancomycin were extremely active against all...
In vitro activities of new beta-lactam antibiotics against Acinetobacter spp.
Garcia, I, Fainstein, V, LeBlanc, B, Bodey, G P
The in vitro activities of new beta-lactam antibiotics was studied and compared with those of other known agents against 51 clinical isolates of Acinetobacter calcoaceticus subsp. anitratus and 23...
Rolston, K V, Nguyen, H T, Ho, D H, LeBlanc, B, Bodey, G P
The in vitro activity of Ro 23-9424 against bacterial isolates from patients with cancer was compared with those of fleroxacin, ciprofloxacin, cefoperazone, and ceftazidime. Ro 23-9424 inhibited the...
Rolston, K V, Ho, D H, LeBlanc, B, Bodey, G P
We evaluated the in vitro activities of 21 different antimicrobial agents against nine clinical isolates of Flavimonas oryzihabitans obtained from patients with cancer. The organisms were susceptible...
Dholakia, N, Rolston, K V, Ho, D H, LeBlanc, B, Bodey, G P
The antibacterial activity of levofloxacin was compared with those of ofloxacin and ciprofloxacin against bacterial isolates from patients with cancer. In general, levofloxacin was as active or was...
The interaction of the ribosomal transcription factor xUBF with the RNA polymerase I core promoter of Xenopus laevis has been studied both at the DNA and protein levels. It is shown that a single...
analyse stochastique ; econometrie ; modeles economiques
Path Dependant Options on Yields in the Affine Term Structure Model.
FINANCIAL MARKETS
Estimation du prix d'une option sur maximum proche de sa maturite.
A correction note on the first passage time of an Ornstein-Uhlenbeck process to a boundary
O. Renault, O. Scaillet, B. Leblanc
This paper provides the derivation of the hitting time density of an Ornstein-Uhlenbeck process to a flat boundary. The derivation relies on a change of measure approach and delivers an explicit...
analyse stochastique ; econometrie ; modeles economiques
Path Dependant Options on Yields in the Affine Term Structure Model.
FINANCIAL MARKETS
Estimation du prix d'une option sur maximum proche de sa maturite.