Family Studies in Coeliac Disease (1974)
MYLOTTE, M., EGAN-MITCHELL, B., FOTTRELL, P. F., MCNICHOLL, B., MCCARTHY, C. F.
Peroral duodenojejunal biopsies were performed on 114 of 195 first degree relatives of 31 index coeliac patients in 28 families. Twelve of these biopsies were characteristic of coeliac disease. Birth...
The 15 g D-xylose absorption test: its application to the study of coeliac disease.
Stevens, F M, Watt, D W, Bourke, M A, McNicholl, B, Fottrell, P F, McCarthy, C F
The absorption of xylose following an oral load of 15 g D-xylose has been studied by serial blood levels in 17 untreated adult coeliac patients, 21 treated coeliac patients, and 30 non-coeliac...
Keane, R, O'Grady, J G, Sheil, J, Stevens, F M, Egan-Mitchell, B, McNicholl, B, ...
Small intestinal lactase, sucrase and alkaline phosphatase activities were measured in histologically normal peroral intestinal biopsies from 477 individuals. Enzyme activities varied with age, sex,...
Intestinal lactase, sucrase, and alkaline phosphatase in 373 patients with coeliac disease.
O'Grady, J G, Stevens, F M, Keane, R, Cryan, E M, Egan-Mitchell, B, McNicholl, B, ...
Lactase, sucrase, and alkaline phosphatase activities were measured in 833 peroral small intestinal biopsies from 373 patients with coeliac disease. Enzyme activities decreased with increasing...
Incidence of Coeliac Disease in the West of Ireland
Mylotte, M., Egan-Mitchell, B., McCarthy, C. F., McNicholl, B.
During an 11-year period the incidence of coeliac disease presenting in children in the West of Ireland has been found to be 1 in 597. When allowance is made for presentation of the disease in adult...
The 15 g D-xylose absorption test: its application to the study of coeliac disease.
Stevens, F M, Watt, D W, Bourke, M A, McNicholl, B, Fottrell, P F, McCarthy, C F
The absorption of xylose following an oral load of 15 g D-xylose has been studied by serial blood levels in 17 untreated adult coeliac patients, 21 treated coeliac patients, and 30 non-coeliac...
Keane, R, O'Grady, J G, Sheil, J, Stevens, F M, Egan-Mitchell, B, McNicholl, B, ...
Small intestinal lactase, sucrase and alkaline phosphatase activities were measured in histologically normal peroral intestinal biopsies from 477 individuals. Enzyme activities varied with age, sex,...
Intestinal lactase, sucrase, and alkaline phosphatase in 373 patients with coeliac disease.
O'Grady, J G, Stevens, F M, Keane, R, Cryan, E M, Egan-Mitchell, B, McNicholl, B, ...
Lactase, sucrase, and alkaline phosphatase activities were measured in 833 peroral small intestinal biopsies from 373 patients with coeliac disease. Enzyme activities decreased with increasing...
Incidence of Coeliac Disease in the West of Ireland
Mylotte, M., Egan-Mitchell, B., McCarthy, C. F., McNicholl, B.
During an 11-year period the incidence of coeliac disease presenting in children in the West of Ireland has been found to be 1 in 597. When allowance is made for presentation of the disease in adult...
Fingerprints in Patients with Coeliac Disease and their Relatives
Mylotte, M., Egan-Mitchell, B., Fottrell, P. F., McNicholl, B., McCarthy, C. F.
The incidence of fingerprint pattern abnormality in 53 patients with coeliac disease and 82 of their relatives was not greater than that found in 58 control subjects. This finding contradicts an...
Reticulin antibodies in patients with coeliac disease and their relatives.
Stevens, F M, Lloyd, R, Egan-Mitchell, B, Mylotte, M J, Fottrell, P F, Wright, R, ...
The sera of 69 index coeliac patients, 121 of their first-degree relatives, and 104 controls were screened for the presence of reticulin antibodies. Among the untreated coeliac patients 75% of adults...
Early or pre-coeliac mucosa: development of gluten enteropathy.
Egan-Mitchell, B, Fottrell, P F, McNicholl, B
Duodenal mucosa showed normal morphology, interepithelial lymphocytes, alkaline phosphatase, and sucrase in a girl with growth retardation and iron deficiency, but normal absorption of lactose and...
Variability of gluten intolerance in treated childhood coeliac disease.
McNicholl, B, Egan-Mitchell, B, Fottrell, P F
Fifty children consecutively attending a clinic for coeliac disease co-operated in a trial; 10 found to have flat mucosa were excluded. Forty children of mean age 9.8 years, whose duodenal or jejunal...
Team triage improves emergency department efficiency
Subash, F, Dunn, F, McNicholl, B, Marlow, J
Objective: To see whether three hours of combined doctor and nurse triage would lead to earlier medical assessment and treatment and whether this benefit would carry on for the rest of the day when...
McAdam, T, McLaughlin, R, McNicholl, B
Objective: To assess the impact of introducing a safer non-touch suturing technique into an inner city emergency department.
Acquired toxoplasmosis in children.
Nine cases of acquired toxoplasmosis, 8 from rural backgrounds, are described, illustrating the wide variety of clinical pictures. Evidence of familial infection was found whenever sought, and was...
Giardiasis in infancy diarrhoea.
Monaghan, H, Garvey, R G, Egan-Mitchell, B, Noone, P, Flynn, J, McNicholl, B
Of 435 infants with diarrhoea aged under one year, 6% were found to have Giardia lamblia; the incidence ranged from 3% housed infants to 12% in itinerant infants. All infants had duodenal fluid and...
Expiration induced femoral flow in neonatal coarctation of aorta.
In a 3 day old infant with coarctation of the aorta a loud Doppler signal synchronous with expiration was present for some hours in the femoral vessels, with only barely audible signals synchronous...
Cerebro-costo-mandibular Syndrome: A New Familial Developmental Disorder
McNicholl, B., Egan-Mitchell, B., Murray, J. P., Doyle, J. F., Kennedy, J. D., Crome, L.
Three sibs with a hitherto unreported syndrome are described, the main features being mental handicap, palatal defects, micrognathia, and severe costovertebral defects, involving segmentation of most...
Decreasing incidence of coeliac disease.
Stevens, F M, Egan-Mitchell, B, Cryan, E, McCarthy, C F, McNicholl, B
Between 1960 and 1974 the incidence of coeliac disease in children under 12 years in County Galway remained fairly constant, but since 1975 it has fallen by 62% and the lowered incidence seems well...
Compliance with gluten free diet in coeliac disease.
Colaco, J, Egan-Mitchell, B, Stevens, F M, Fottrell, P F, McCarthy, C F, McNicholl, B
Fifty two children in whom coeliac disease was confirmed by persistent enteropathy while they were taking gluten were monitored to assess the effects of compliance with a gluten free diet (GFD)....
The epidemiology of major trauma in Northern Ireland.
In a one year population based study of major trauma (Injury Severity Score greater than 15) reaching hospitals in Northern Ireland in 1990/91 the incidence was 23.2 per 100,000 of the population or...