DDEC: Dragon database of genes implicated in esophageal cancer (2009)
Essack Magbubah, Radovanovic Aleksandar, Schaefer Ulf, Schmeier Sebastian, Seshadri Sundararajan, Christoffels Alan, ...
Abstract Background Esophageal cancer ranks eighth in order of cancer occurrence. Its lethality primarily stems from inability to detect the disease during the early organ-confined stage and the lack...
Meier Stuart, Bastian René, Donaldson Lara, Murray Shane, Bajic Vladimir, Gehring Chris
Abstract Background Plant natriuretic peptides (PNPs) are a class of systemically mobile molecules distantly related to expansins. While several physiological responses to PNPs have been reported,...
Kaur Mandeep, Schmeier Sebastian, MacPherson Cameron, Hofmann Oliver, Hide Winston, Taylor Stephen, ...
Abstract Background About 5% of western populations are afflicted by autoimmune diseases many of which are affected by sex hormones. Autoimmune diseases are complex and involve many genes....
DDESC: Dragon database for exploration of sodium channels in human (2008)
Sagar Sunil, Kaur Mandeep, Dawe Adam, Seshadri Sundararajan, Christoffels Alan, Schaefer Ulf, ...
Abstract Background Sodium channels are heteromultimeric, integral membrane proteins that belong to a superfamily of ion channels. The mutations in genes encoding for sodium channel proteins have...
Cheng Chen, Yun Kil-Young, Ressom Habtom, Mohanty Bijayalaxmi, Bajic Vladimir, Jia Yulin, ...
Abstract Background Plants respond to low temperature through an intricately coordinated transcriptional network. The CBF/DREB-regulated network of genes has been shown to play a prominent role in...
Computational selection and prioritization of candidate genes for Fetal Alcohol Syndrome (2007)
Lombard Zané, Tiffin Nicki, Hofmann Oliver, Bajic Vladimir, Hide Winston, Ramsay Michèle
Abstract Background Fetal alcohol syndrome (FAS) is a serious global health problem and is observed at high frequencies in certain South African communities. Although in utero alcohol exposure is the...
Computational promoter analysis of mouse, rat and human antimicrobial peptide-coding genes (2006)
Brahmachary Manisha, Schönbach Christian, Yang Liang, Huang Enli, Tan Sin, Chowdhary Rajesh, ...
Abstract Background Mammalian antimicrobial peptides (AMPs) are effectors of the innate immune response. A multitude of signals coming from pathways of mammalian pathogen/pattern recognition...