Byung Cheon Lee

MsrB1 (Methionine-R-sulfoxide Reductase 1) Knock-out Mice: Roles of MsrB1 in Redox Regulation and Identification of a Novel Selenoprotein Form (2009)

Fomenko, Dmitri E., Novoselov, Sergey V., Natarajan, Sathish Kumar, Lee, Byung Cheon, Koc, Ahmet, Carlson, Bradley A., ...

Protein oxidation has been linked to accelerated aging and is a contributing factor to many diseases. Methionine residues are particularly susceptible to oxidation, but the resulting mixture of...

Overexpression of Methionine-R-Sulfoxide Reductases has No iInfluence on Fruit Fly Aging (2009)

Shchedrina, Valentina A., Vorbrüggen, Gerd, Lee, Byung Cheon, Kim, Hwa-Young, Kabil, Hadise, Harshman, Lawrence G., ...

Methionine sulfoxide reductases (Msrs) are enzymes that repair oxidized methionine residues in proteins. This function implicated Msrs in antiox¬idant defense and the regulation of aging. There are...

Mammals Reduce Methionine-S-sulfoxide with MsrA and Are Unable to Reduce Methionine-R-sulfoxide, and This Function Can Be Restored with a Yeast Reductase*S⃞

Lee, Byung Cheon, Le, Dung Tien, Gladyshev, Vadim N.

Methionine is an essential amino acid in mammals at the junction of methylation, protein synthesis, and sulfur pathways. However, this amino acid is highly susceptible to oxidation, resulting in a...