Christian Hucke

Expression und Aktivität der Indolamin 2,3-dioxygenase in humanen Epithelzellen: Regulation durch Stickstoffmonoxid (2007)

Hucke, Christian

Die vorliegende Dissertation befasste sich thematisch mit der Interaktion zweier immunologisch bedeutsamer Mechanismen in humanen Zellen. Der erste Mechanismus, der Abbau der essentiellen Aminosäure...

A new efficient trial design for assessing reliability of ankle-brachial index measures by three different observer groups (2006)

Endres, Heinz G, Hucke, Christian, Holland-Letz, Tim, Trampisch, Hans-Joachim

Abstract Background The usual method of assessing the variability of a measure such as the ankle brachial index (ABI) as a function of different observer groups is to obtain repeated measurements....

Interleukin-1 Inhibits Gamma Interferon-Induced Bacteriostasis in Human Uroepithelial Cells

Däubener, Walter, Hucke, Christian, Seidel, Kerstin, Hadding, Ulrich, MacKenzie, Colin R.

The most prominent gamma interferon (IFN-γ)-induced antimicrobial effector mechanisms are the induction of nitric oxide (NO) synthase (NOS) and of indoleamine 2,3-dioxygenase (IDO) activity. We have...

Restriction of Toxoplasma gondii Growth in Human Brain Microvascular Endothelial Cells by Activation of Indoleamine 2,3-Dioxygenase

Däubener, Walter, Spors, Birgit, Hucke, Christian, Adam, Rüdiger, Stins, Monique, Kim, Kwang Sik, ...

One of the first steps in the development of cerebral toxoplasmosis is the penetration of the blood-brain barrier, which is comprised of microvascular endothelial cells. We examined the capacity of...

Nitric Oxide-Mediated Regulation of Gamma Interferon-Induced Bacteriostasis: Inhibition and Degradation of Human Indoleamine 2,3-Dioxygenase

Hucke, Christian, MacKenzie, Colin R., Adjogble, Koku D. Z., Takikawa, Osamu, Däubener, Walter

Tryptophan depletion resulting from indoleamine 2,3-dioxygenase (IDO) activity within the kynurenine pathway is one of the most prominent gamma interferon (IFN-γ)-inducible antimicrobial effector...

Interleukin-1 Inhibits Gamma Interferon-Induced Bacteriostasis in Human Uroepithelial Cells

Däubener, Walter, Hucke, Christian, Seidel, Kerstin, Hadding, Ulrich, MacKenzie, Colin R.

The most prominent gamma interferon (IFN-γ)-induced antimicrobial effector mechanisms are the induction of nitric oxide (NO) synthase (NOS) and of indoleamine 2,3-dioxygenase (IDO) activity. We have...

Restriction of Toxoplasma gondii Growth in Human Brain Microvascular Endothelial Cells by Activation of Indoleamine 2,3-Dioxygenase

Däubener, Walter, Spors, Birgit, Hucke, Christian, Adam, Rüdiger, Stins, Monique, Kim, Kwang Sik, ...

One of the first steps in the development of cerebral toxoplasmosis is the penetration of the blood-brain barrier, which is comprised of microvascular endothelial cells. We examined the capacity of...

Nitric Oxide-Mediated Regulation of Gamma Interferon-Induced Bacteriostasis: Inhibition and Degradation of Human Indoleamine 2,3-Dioxygenase

Hucke, Christian, MacKenzie, Colin R., Adjogble, Koku D. Z., Takikawa, Osamu, Däubener, Walter

Tryptophan depletion resulting from indoleamine 2,3-dioxygenase (IDO) activity within the kynurenine pathway is one of the most prominent gamma interferon (IFN-γ)-inducible antimicrobial effector...