conditional experiments with a (2008)
Rainer König, Danila Baldessari, Nicolas Pollet, Christof Niehrs, Dr. Rainer König
of gene expression ratios for cDNA microarrays in multi-
Nicolas Pollet, Heiko A. Schmidt, Volker Gawantka, Martin Vingron, Christof Niehrs
Axeldb is a database storing and integrating gene expression patterns and DNA sequences identified in a large-scale in situ hybridization study in Xenopus laevis embryos. The data are organised in a...
Rainer Koè Nig, Danila Baldessari, Nicolas Pollet, Christof Niehrs, Roland Eils
Reliability of gene expression ratios for cDNA
König, Rainer, Baldessari, Danila, Pollet, Nicolas, Niehrs, Christof, Eils, Roland
In a typical gene expression profiling experiment with multiple conditions, a common reference sample is used for co‐hybridization with the samples to yield expression ratios. Differential...
Dkk1 and noggin cooperate in mammalian head induction (2003)
Del Barco Barrantes, Ivan, Davidson, Gary, Gröne, Hermann-Josef, Westphal, Heiner, Niehrs, Christof
Growth factor antagonists play important roles in mediating the inductive effects of the Spemann organizer in amphibian embryos and its equivalents in other vertebrates. Dual inhibition of Wnt and...
Dkk1 and noggin cooperate in mammalian head induction (2003)
Del Barco Barrantes, Ivan, Davidson, Gary, Gröne, Hermann-Josef, Westphal, Heiner, Niehrs, Christof
Growth factor antagonists play important roles in mediating the inductive effects of the Spemann organizer in amphibian embryos and its equivalents in other vertebrates. Dual inhibition of Wnt and...
Nrarp is a novel intracellular component of the Notch signaling pathway (2001)
Lamar, Elise, Deblandre, Gisèle, Wettstein, Daniel, Gawantka, Volker, Pollet, Nicolas, Niehrs, Christof, ...
Axeldb: a Xenopus laevis database focusing on gene expression (2000)
Pollet, Nicolas, Schmidt, Heiko A., Gawantka, Volker, Vingron, Martin, Niehrs, Christof
Axeldb is a database storing and integrating gene expression patterns and DNA sequences identified in a large-scale in situ hybridization study in Xenopus laevis embryos. The data are organised in a...
Periodic repression of Notch pathway genes governs the segmentation of Xenopus embryos (1999)
Jen, Wui-Chuong, Gawantka, Volker, Pollet, Nicolas, Niehrs, Christof, Kintner, Chris
Charakterisierung und Reinigung von Tyrosylprotein Sulfotransferase. (1990)
Heidelberg, Univ., Diss., 1990 (Nicht f.d. Austausch).
Beisswanger, Roland, Corbeil, Denis, Vannier, Christian, Thiele, Christoph, Dohrmann, Ulrike, Kellner, Roland, ...
Tyrosylprotein sulfotransferase (TPST) is a 54- to 50-kDa integral membrane glycoprotein of the trans-Golgi network found in essentially all tissues investigated, catalyzing the tyrosine O-sulfation...
RanGTP-Regulated Interactions of CRM1 with Nucleoporins and a Shuttling DEAD-Box Helicase
Askjaer, Peter, Bachi, Angela, Wilm, Matthias, Bischoff, F. Ralf, Weeks, Daniel L., Ogniewski, Vera, ...
CRM1 is an export receptor mediating rapid nuclear exit of proteins and RNAs to the cytoplasm. CRM1 export cargoes include proteins with a leucine-rich nuclear export signal (NES) that bind directly...
Axeldb: a Xenopus laevis database focusing on gene expression
Pollet, Nicolas, Schmidt, Heiko A., Gawantka, Volker, Vingron, Martin, Niehrs, Christof
Axeldb is a database storing and integrating gene expression patterns and DNA sequences identified in a large-scale in situ hybridization study in Xenopus laevis embryos. The data are organised in a...
Dkk1 and noggin cooperate in mammalian head induction
Del Barco Barrantes, Ivan, Davidson, Gary, Gröne, Hermann-Josef, Westphal, Heiner, Niehrs, Christof
Growth factor antagonists play important roles in mediating the inductive effects of the Spemann organizer in amphibian embryos and its equivalents in other vertebrates. Dual inhibition of Wnt and...
Periodic repression of Notch pathway genes governs the segmentation of Xenopus embryos
Jen, Wui-Chuong, Gawantka, Volker, Pollet, Nicolas, Niehrs, Christof, Kintner, Chris
During the development of the vertebrate embryo, genes encoding components of the Notch signaling pathway are required for subdividing the paraxial mesoderm into repeating segmental structures,...
König, Rainer, Baldessari, Danila, Pollet, Nicolas, Niehrs, Christof, Eils, Roland
In a typical gene expression profiling experiment with multiple conditions, a common reference sample is used for co-hybridization with the samples to yield expression ratios. Differential expression...
Transcriptional regulation of BMP4 synexpression in transgenic Xenopus
Karaulanov, Emil, Knöchel, Walter, Niehrs, Christof
Synexpression groups are genetic modules composed of genes that share both a complex expression pattern and the biological process in which they function. Here we investigate the regulation of BMP4...
Nrarp is a novel intracellular component of the Notch signaling pathway
Lamar, Elise, Deblandre, Gisèle, Wettstein, Daniel, Gawantka, Volker, Pollet, Nicolas, Niehrs, Christof, ...
The Lin12/Notch receptors regulate cell fate during embryogenesis by activating the expression of downstream target genes. These receptors signal via their intracellular domain (ICD), which is...
Generation and Characterization of dickkopf3 Mutant Mice
Del Barco Barrantes, Ivan, Montero-Pedrazuela, Ana, Guadaño-Ferraz, Ana, Obregon, Maria-Jesus, Martinez De Mena, Raquel, Gailus-Durner, Valérie, ...
dickkopf (dkk) genes encode a small family of secreted Wnt antagonists, except for dkk3, which is divergent and whose function is poorly understood. Here, we describe the generation and...
Beisswanger, Roland, Corbeil, Denis, Vannier, Christian, Thiele, Christoph, Dohrmann, Ulrike, Kellner, Roland, ...
Tyrosylprotein sulfotransferase (TPST) is a 54- to 50-kDa integral membrane glycoprotein of the trans-Golgi network found in essentially all tissues investigated, catalyzing the tyrosine O-sulfation...
RanGTP-Regulated Interactions of CRM1 with Nucleoporins and a Shuttling DEAD-Box Helicase
Askjaer, Peter, Bachi, Angela, Wilm, Matthias, Bischoff, F. Ralf, Weeks, Daniel L., Ogniewski, Vera, ...
CRM1 is an export receptor mediating rapid nuclear exit of proteins and RNAs to the cytoplasm. CRM1 export cargoes include proteins with a leucine-rich nuclear export signal (NES) that bind directly...
Axeldb: a Xenopus laevis database focusing on gene expression
Pollet, Nicolas, Schmidt, Heiko A., Gawantka, Volker, Vingron, Martin, Niehrs, Christof
Axeldb is a database storing and integrating gene expression patterns and DNA sequences identified in a large-scale in situ hybridization study in Xenopus laevis embryos. The data are organised in a...
Dkk1 and noggin cooperate in mammalian head induction
Del Barco Barrantes, Ivan, Davidson, Gary, Gröne, Hermann-Josef, Westphal, Heiner, Niehrs, Christof
Growth factor antagonists play important roles in mediating the inductive effects of the Spemann organizer in amphibian embryos and its equivalents in other vertebrates. Dual inhibition of Wnt and...
Nrarp is a novel intracellular component of the Notch signaling pathway
Lamar, Elise, Deblandre, Gisèle, Wettstein, Daniel, Gawantka, Volker, Pollet, Nicolas, Niehrs, Christof, ...
The Lin12/Notch receptors regulate cell fate during embryogenesis by activating the expression of downstream target genes. These receptors signal via their intracellular domain (ICD), which is...
Periodic repression of Notch pathway genes governs the segmentation of Xenopus embryos
Jen, Wui-Chuong, Gawantka, Volker, Pollet, Nicolas, Niehrs, Christof, Kintner, Chris
During the development of the vertebrate embryo, genes encoding components of the Notch signaling pathway are required for subdividing the paraxial mesoderm into repeating segmental structures,...
König, Rainer, Baldessari, Danila, Pollet, Nicolas, Niehrs, Christof, Eils, Roland
In a typical gene expression profiling experiment with multiple conditions, a common reference sample is used for co-hybridization with the samples to yield expression ratios. Differential expression...
Transcriptional regulation of BMP4 synexpression in transgenic Xenopus
Karaulanov, Emil, Knöchel, Walter, Niehrs, Christof
Synexpression groups are genetic modules composed of genes that share both a complex expression pattern and the biological process in which they function. Here we investigate the regulation of BMP4...
Generation and Characterization of dickkopf3 Mutant Mice
Del Barco Barrantes, Ivan, Montero-Pedrazuela, Ana, Guadaño-Ferraz, Ana, Obregon, Maria-Jesus, Martinez De Mena, Raquel, Gailus-Durner, Valérie, ...
dickkopf (dkk) genes encode a small family of secreted Wnt antagonists, except for dkk3, which is divergent and whose function is poorly understood. Here, we describe the generation and...
A role for fibronectin-leucine-rich transmembrane cell-surface proteins in homotypic cell adhesion
Karaulanov, Emil E, Böttcher, Ralph T, Niehrs, Christof
The fibronectin-leucine-rich transmembrane (FLRT) family of leucine-rich repeat (LRR) proteins is implicated in fibroblast growth factor (FGF) signalling, early embryonic development and neurite...
Caneparo, Luca, Huang, Ya-Lin, Staudt, Nicole, Tada, Masasumi, Ahrendt, Reiner, Kazanskaya, Olga, ...
Dickkopf-1 (Dkk1) is a secreted protein that negatively modulates the Wnt/βcatenin pathway. Lack of Dkk1 function affects head formation in frog and mice, supporting the idea that Dkk1 acts as a...
TGF-β signaling-mediated morphogenesis: modulation of cell adhesion via cadherin endocytosis
Ogata, Souichi, Morokuma, Junji, Hayata, Tadayoshi, Kolle, Gabriel, Niehrs, Christof, Ueno, Naoto, ...
The molecular mechanisms governing the cell behaviors underlying morphogenesis remain a major focus of research in both developmental biology and cancer biology. TGF-β ligands control cell fate...
Targeted Disruption of the Wnt Regulator Kremen Induces Limb Defects and High Bone Density▿ †
Ellwanger, Kristina, Saito, Hiroaki, Clément-Lacroix, Philippe, Maltry, Nicole, Niedermeyer, Joachim, Lee, Woon Kyu, ...
Kremen1 and Kremen2 (Krm1 and Krm2) are transmembrane coreceptors for Dickkopf1 (Dkk1), an antagonist of Wnt/β-catenin signaling. The physiological relevance of Kremen proteins in mammals as Wnt...
Unc5B Interacts with FLRT3 and Rnd1 to Modulate Cell Adhesion in Xenopus Embryos
Karaulanov, Emil, Böttcher, Ralph T., Stannek, Peter, Wu, Wei, Rau, Marlene, Ogata, Souichi, ...
The FLRT family of transmembrane proteins has been implicated in the regulation of FGF signalling, neurite outgrowth, homotypic cell sorting and cadherin-mediated adhesion. In an expression screen we...