Christopher Wv Hogue

BMC 32002, (2007)

Bmc Bioinformatics, Michel Dumontier, Katerina Michalickova, Christopher Wv Hogue

Background: An organism's ability to adapt to its particular environmental niche is of fundamental importance to its survival and proliferation. In the largest study of its kind, we sought to...

Methodology article NBLAST: a cluster variant of BLAST for NxN comparisons (2007)

Bmc Bioinformatics, Michel Dumontier, Christopher Wv Hogue

© 2002 Dumontier and Hogue; licensee BioMed Central Ltd. Verbatim copying and redistribution of this article are permitted in any medium for any purpose, provided this notice is preserved along with...

BioMed Central (2007)

Bmc Bioinformatics, Ian Donaldson, Joel Martin, Berry De Bruijn, Cheryl Wolting, Vicki Lay, ...

Research article PreBIND and Textomy – mining the biomedical literature for protein-protein interactions using a support vector machine

Methodology article x BioMed Central (2007)

Bmc Bioinformatics, Doron Betel, Christopher Wv Hogue

Background: Biologists are often interested in performing a simple database search to identify proteins or genes that contain a well-defined sequence pattern. Many databases do not provide...

Article type Methodology article (2007)

Bmc Bioinformatics, Gary D Bader, Michel Dumontier, Hao C Lieu, Ruth Isserlin, Christopher Wv Hogue, ...

This 'Manuscript PDF ' corresponds to the article as it appeared upon acceptance. The fully-formatted PDF version will become available within a few days, from the URL listed below....

Domain-based small molecule binding site annotation (2006)

Snyder, Kevin A, Feldman, Howard J, Dumontier, Michel, Salama, John J, Hogue, Christopher WV

Abstract Background Accurate small molecule binding site information for a protein can facilitate studies in drug docking, drug discovery and function prediction, but small molecule binding site...

BMC Bioinformatics BioMed Central Database Domain-based small molecule binding site annotation (2006)

Kevin A Snyder, Howard J Feldman, Michel Dumontier, John J Salama, Christopher Wv Hogue

© 2006Snyder et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License

PreBIND and Textomy – mining the biomedical literature for protein-protein interactions using a support vector machine (2003)

Donaldson, Ian, Martin, Joel, De Bruijn, Berry, Wolting, Cheryl, Lay, Vicki, Tuekam, Brigitte, ...

Abstract Background The majority of experimentally verified molecular interaction and biological pathway data are present in the unstructured text of biomedical journal articles where they are...

An automated method for finding molecular complexes in large protein interaction networks (2003)

Bader, Gary D, Hogue, Christopher WV

Abstract Background Recent advances in proteomics technologies such as two-hybrid, phage display and mass spectrometry have enabled us to create a detailed map of biomolecular interaction networks....

BMC Bioinformatics Methodology article (2003)

Gary D Bader, Christopher Wv Hogue

Background: Recent advances in proteomics technologies such as two-hybrid, phage display and mass spectrometry have enabled us to create a detailed map of biomolecular interaction networks. Initial...

Species-specific protein sequence and fold optimizations (2002)

Dumontier, Michel, Michalickova, Katerina, Hogue, Christopher WV

Abstract Background An organism's ability to adapt to its particular environmental niche is of fundamental importance to its survival and proliferation. In the largest study of its kind, we sought to...

SeqHound: biological sequence and structure database as a platform for bioinformatics research (2002)

Michalickova, Katerina, Bader, Gary D, Dumontier, Michel, Lieu, Hao, Betel, Doron, Isserlin, Ruth, ...

Abstract Background SeqHound has been developed as an integrated biological sequence, taxonomy, annotation and 3-D structure database system. It provides a high-performance server platform for...

Kangaroo – A pattern-matching program for biological sequences (2002)

Betel, Doron, Hogue, Christopher WV

Abstract Background Biologists are often interested in performing a simple database search to identify proteins or genes that contain a well-defined sequence pattern. Many databases do not provide...

NBLAST: a cluster variant of BLAST for NxN comparisons (2002)

Dumontier, Michel, Hogue, Christopher WV

Abstract Background The BLAST algorithm compares biological sequences to one another in order to determine shared motifs and common ancestry. However, the comparison of all non-redundant (NR)...