Colin R. MacKenzie

Interleukin-1 Inhibits Gamma Interferon-Induced Bacteriostasis in Human Uroepithelial Cells

Däubener, Walter, Hucke, Christian, Seidel, Kerstin, Hadding, Ulrich, MacKenzie, Colin R.

The most prominent gamma interferon (IFN-γ)-induced antimicrobial effector mechanisms are the induction of nitric oxide (NO) synthase (NOS) and of indoleamine 2,3-dioxygenase (IDO) activity. We have...

Nitric Oxide-Mediated Regulation of Gamma Interferon-Induced Bacteriostasis: Inhibition and Degradation of Human Indoleamine 2,3-Dioxygenase

Hucke, Christian, MacKenzie, Colin R., Adjogble, Koku D. Z., Takikawa, Osamu, Däubener, Walter

Tryptophan depletion resulting from indoleamine 2,3-dioxygenase (IDO) activity within the kynurenine pathway is one of the most prominent gamma interferon (IFN-γ)-inducible antimicrobial effector...

Interleukin-1 Inhibits Gamma Interferon-Induced Bacteriostasis in Human Uroepithelial Cells

Däubener, Walter, Hucke, Christian, Seidel, Kerstin, Hadding, Ulrich, MacKenzie, Colin R.

The most prominent gamma interferon (IFN-γ)-induced antimicrobial effector mechanisms are the induction of nitric oxide (NO) synthase (NOS) and of indoleamine 2,3-dioxygenase (IDO) activity. We have...

Nitric Oxide-Mediated Regulation of Gamma Interferon-Induced Bacteriostasis: Inhibition and Degradation of Human Indoleamine 2,3-Dioxygenase

Hucke, Christian, MacKenzie, Colin R., Adjogble, Koku D. Z., Takikawa, Osamu, Däubener, Walter

Tryptophan depletion resulting from indoleamine 2,3-dioxygenase (IDO) activity within the kynurenine pathway is one of the most prominent gamma interferon (IFN-γ)-inducible antimicrobial effector...