Ambient Air Pollution and Risk of Congenital Anomalies in England, 1991-99 (2009)
Dolk, H., Armstrong, B., Lachowycz, K., Vrijheid, M., Rankin, J., Abramsky, L., ...
OBJECTIVES: To investigate whether there is an association between risk of congenital anomaly and annual ward level exposure to air pollution in England during the 1990s. METHODS: A geographical...
Dolk, H., Jentink, J., Loane, M., Morris, J., De Jong-van Den Berg, L.T., Calzolari, E., ...
Objective: to investigate whether first trimester exposure to lamotrigine (LTG) monotherapy is specifically associated with an increased risk of orofacial clefts (OCs) relative to other...
Ramsay, L., Howe, D.T., Wellesley, D.
Objective: To determine whether parents might be distressed if approached to take part in long-term follow-up of their children's health and development. Methods: A short, closed format anonymous...
Ramsay, L., Howe, D.T., Wellesley, D.
Objective To determine whether parents might be distressed if approached to take part in long-term follow-up of their children's health and development. Methods A short, closed format anonymous...
Blyth, M., Howe, D., Gnanapragasam, J., Wellesley, D.
Objective To describe the sensitivity of fetal anomaly scanning at detecting transposition of the great arteries (TGA) and to investigate whether prenatal detection improves survival. Design...
Blyth, M., Howe, D., Gnanapragasam, J., Wellesley, D.
OBJECTIVE: To describe the sensitivity of fetal anomaly scanning at detecting transposition of the great arteries (TGA) and to investigate whether prenatal detection improves survival. DESIGN:...
Geographic variation and localised clustering of congenital anomalies in Great Britain (2007)
Armstrong, B.G., Dolk, H., Pattenden, S., Vrijheid, M., Loane, M., Rankin, J., ...
Background Environmental pollution as a cause of congenital anomalies is sometimes suspected because of clustering of anomalies in areas of higher exposure. This highlights questions around spatial...
Geographic variation and localised clustering of congenital anomalies in Great Britain (2007)
Armstrong, B, Dolk, H, Pattenden, S, Loane, M, Rankin, J, Dunn, C, ...
Prevalence of congenital anomalies in five British regions, 1991-99 (2005)
Rankin, J., Pattenden, S., Abramsky, L., Boyd, P., Jordan, H., Stone, D., ...
Aims: To describe trends in total and live birth prevalence, regional differences in prevalence, and outcome of pregnancy of selected congenital anomalies. Methods: Population based registry study of...
Rankin, J., Pattenden, S., Abramsky, L., Boyd, P., Jordan, H., Stone, D., ...
AIMS: To describe trends in total and live birth prevalence, regional differences in prevalence, and outcome of pregnancy of selected congenital anomalies. METHODS: Population based registry study of...
Congenital anomaly surveillance in England—ascertainment deficiencies in the national system (2005)
Boyd, P A, Armstrong, B, Dolk, H, Botting, B, Pattenden, S, Abramsky, L, ...
Objective Firstly, to assess the completeness of ascertainment in the National Congenital Anomaly System (NCAS), the basis for congenital anomaly surveillance in England and Wales, and its variation...
An aetiological classification of birth defects for epidemiological research (2005)
Wellesley, D., Boyd, P., Dolk, H., Pattenden, S.
Background: Congenital anomaly registers collect data on antenatally and postnatally detected anomalies for surveillance, research, and public health purposes. Each anomaly is coded using the...
Congenital anomaly surveillance in England-ascertainment deficiencies in the national system (2005)
Boyd, P.A., Armstrong, B., Dolk, H., Botting, B., Pattenden, S., Abramsky, L., ...
Objective Firstly, to assess the completeness of ascertainment in the National Congenital Anomaly System (NCAS), the basis for congenital anomaly surveillance in England and Wales, and its variation...
An aetiological classification of birth defects for epidemiological research (2005)
Wellesley, D., Boyd, P., Dolk, H., Pattenden, S.
BACKGROUND: Congenital anomaly registers collect data on antenatally and postnatally detected anomalies for surveillance, research, and public health purposes. Each anomaly is coded using the...
Prevalence of congenital anomalies in five British regions, 1991-99 (2005)
Rankin, J, Pattenden, S, Abramsky, L, Boyd, P, Jordan, H, Stone, D, ...
SHOX mutations in a family and a fetus with Langer mesomelic dwarfism (2004)
Thomas, N. S., Maloney, V., Bass, P., Mulik, V., Wellesley, D., Castle, B.
Léri-Weill dyschondrosteosis (LWD) and Langer mesomelic dysplasia (LMD) are caused by mutations in the SHOX gene. LWD results from haploinsufficiency and is dominantly inherited, while the more...
Wellesley, D., De Vigan, C., Baena, N., Cariati, E., Stoll, C., Boyd, P.A., ...
The objective of this study was to evaluate the contribution of ultrasound scanning to the prenatal detection of trisomy 21 in a large unselected European population. Data from 19 congenital...
Unusual prenatal presentation of Beckwith-Wiedemann syndrome (2004)
Mulik, V., Wellesley, D., Sawdy, R., Howe, D.T.
When Beckwith-Wiedemann syndrome (BWS) is detected prenatally, it is usually on the basis of macroglossia, exomphalos or enlarged kidneys. We describe a case that presented as gross hepatomegaly and...
SHOX mutations in a family and a fetus with Langer mesomelic dwarfism (2004)
Thomas, N.S., Maloney, V., Bass, P., Mulik, V., Wellesley, D., Castle, B.
Leri-Weill dyschondrosteosis (LWD) and Langer mesomelic dysplasia (LMD) are caused by mutations in the SHOX gene. LWD results from haploinsufficiency and is dominantly inherited, while the more...
Wellesley, D., De Vigan, C., Baena, N., Cariati, E., Stoll, C., Boyd, P.A., ...
The objective of this study was to evaluate the contribution of ultrasound scanning to the prenatal detection of trisomy 21 in a large unselected European population. Data from 19 congenital...
Congenital heart disease, deafness and duplications of 3q: refining a new critical region (2003)
Wilson, D., Cox, H., Fiegler, H., Wilkinson, K., Fowler, D., Moore, K., ...
Congenital anomaly surveillance in England—ascertainment deficiencies in the national system
Boyd, P A, Armstrong, B, Dolk, H, Botting, B, Pattenden, S, Abramsky, L, ...
Objective Firstly, to assess the completeness of ascertainment in the National Congenital Anomaly System (NCAS), the basis for congenital anomaly surveillance in England and Wales, and its variation...
Foy, C, Newton, V, Wellesley, D, Harris, R, Read, A P
We have demonstrated close linkage between the locus for the autosomal dominant Waardenburg syndrome type I and the placental alkaline phosphatase locus on chromosome 2q37. In five families the peak...
Congenital anomaly surveillance in England—ascertainment deficiencies in the national system
Boyd, P A, Armstrong, B, Dolk, H, Botting, B, Pattenden, S, Abramsky, L, ...
Objective Firstly, to assess the completeness of ascertainment in the National Congenital Anomaly System (NCAS), the basis for congenital anomaly surveillance in England and Wales, and its variation...
Foy, C, Newton, V, Wellesley, D, Harris, R, Read, A P
We have demonstrated close linkage between the locus for the autosomal dominant Waardenburg syndrome type I and the placental alkaline phosphatase locus on chromosome 2q37. In five families the peak...
Asymmetry and skin pigmentary anomalies in chromosome mosaicism.
Woods, C G, Bankier, A, Curry, J, Sheffield, L J, Slaney, S F, Smith, K, ...
We report six persons mosaic for a chromosome anomaly. All were mentally retarded and dysmorphic. Unilateral or asymmetrical features were found in all cases, in one an unusual transverse terminal...
Wellesley, D, Young, I D, Cooke, P, Callen, D F, Hockey, A
We present a family segregating for t(5;9)(p15.1;q34.13). Two cases with der(5),t(5;9), resulting in a partial duplication 9q34.13----qter and partial deletion of 5p15.12----pter, were ascertained....
Interstitial deletion of chromosome 17 (del(17)(q22q23.3)) confirms a link with oesophageal atresia
MARSH, A., WELLESLEY, D., BURGE, D., ASHTON, M., BROWNE, C., DENNIS, N., ...
An aetiological classification of birth defects for epidemiological research
Wellesley, D, Boyd, P, Dolk, H, Pattenden, S
Background: Congenital anomaly registers collect data on antenatally and postnatally detected anomalies for surveillance, research, and public health purposes. Each anomaly is coded using the...
Prevalence of congenital anomalies in five British regions, 1991–99
Rankin, J, Pattenden, S, Abramsky, L, Boyd, P, Jordan, H, Stone, D, ...
Aims: To describe trends in total and live birth prevalence, regional differences in prevalence, and outcome of pregnancy of selected congenital anomalies.