Darren P. Martin

Details der Publikationsliste

Zeitraum

2006 - 2009

Anzahl

15

Co-Autoren

Comparative analysis of Panicum streak virus and Maize streak virus diversity, recombination patterns and phylogeography (2009)

Varsani, Arvind, Monjane, Aderito L, Donaldson, Lara, Oluwafemi, Sunday, Zinga, Innocent, Komba, Ephrem K, ...

Abstract Background Panicum streak virus (PanSV; Family Geminiviridae ; Genus Mastrevirus ) is a close relative of Maize streak virus (MSV), the most serious viral threat to maize production in...

Experimental evidence indicating that mastreviruses probably did not co-diverge with their hosts (2009)

Harkins, Gordon W, Delport, Wayne, Duffy, Siobain, Wood, Natasha, Monjane, Adérito L, Owor, Betty E, ...

Abstract Background Despite the demonstration that geminiviruses, like many other single stranded DNA viruses, are evolving at rates similar to those of RNA viruses, a recent study has suggested that...

Identifying recombinants in human and primate immunodeficiency virus sequence alignments using quartet scanning (2009)

Lemey, Philippe, Lott, Martin, Martin, Darren P, Moulton, Vincent

Abstract Background Recombination has a profound impact on the evolution of viruses, but characterizing recombination patterns in molecular sequences remains a challenging endeavor. Despite its...

Identifying recombinants in human and primate immunodeficiency virus sequence alignments using quartet scanning (2009)

Lott, Martin, Martin, Darren P, Moulton, Vincent

Background: Recombination has a profound impact on the evolution of viruses, but characterizing recombination patterns in molecular sequences remains a challenging endeavor. Despite its importance in...

A highly divergent South African geminivirus species illuminates the ancient evolutionary history of this family (2009)

Varsani, Arvind, Shepherd, Dionne N, Dent, Kyle, Monjane, Aderito L, Rybicki, Edward P, Martin, Darren P

Abstract Background We have characterised a new highly divergent geminivirus species, Eragrostis curvula streak virus (ECSV), found infecting a hardy perennial South African wild grass. ECSV...

Conserved positive selection signals in gp41 across multiple subtypes and difference in selection signals detectable in gp41 sequences sampled during acute and chronic HIV-1 subtype C infection (2008)

Bandawe, Gama P, Martin, Darren P, Treurnicht, Florette, Mlisana, Koleka, Karim, Salim, Williamson, Carolyn, ...

Abstract Background The high diversity of HIV variants driving the global AIDS epidemic has caused many to doubt whether an effective vaccine against the virus is possible. However, by identifying...

Experimental observations of rapid Maize streak virus evolution reveal a strand-specific nucleotide substitution bias (2008)

Van Der Walt, Eric, Martin, Darren P, Varsani, Arvind, Polston, Jane E, Rybicki, Edward P

Abstract Background Recent reports have indicated that single-stranded DNA (ssDNA) viruses in the taxonomic families Geminiviridae , Parvoviridae and Anellovirus may be evolving at rates of ~10 -4...

Robust inference of positive selection from recombining coding sequences (2006)

Scheffler, Konrad, Martin, Darren P., Seoighe, Cathal

Motivation: Accurate detection of positive Darwinian selection can provide important insights to researchers investigating the evolution of pathogens. However, many pathogens (particularly viruses)...

Molecular Mechanisms of Recombination Restriction in the Envelope Gene of the Human Immunodeficiency Virus

Simon-Loriere, Etienne, Galetto, Roman, Hamoudi, Meriem, Archer, John, Lefeuvre, Pierre, Martin, Darren P., ...

The ability of pathogens to escape the host's immune response is crucial for the establishment of persistent infections and can influence virulence. Recombination has been observed to contribute to...