A thermodynamic framework for the magnesium-dependent folding of RNA (2003)
Misra, Vinod K., Shiman, Ross, Draper, David E.
The goal of this review is to present a unified picture of the relationship between ion binding and RNA folding based on recent theoretical and computational advances. In particular, we present a...
Blyn, Lawrence B., Risen, Lisa M., Griffey, Richard H., Draper, David E.
Antibiotics that inhibit ribosomal function may do so by one of several mechanisms, including the induction of incorrect RNA folding or prevention of protein and/or RNA conformational...
Morse, Sarah E., Draper, David E.
Thermodynamic parameters are presented for 12 different RNA duplexes containing A·A, A·G, G·A and G·G mismatches flanked by C·G base pairs. UV melting studies were conducted under three...
Ribosomal protein L11 and an antibiotic, thiostrepton, bind to the same highly conserved region of large subunit ribosomal RNA and stabilize a set of NH4+-dependent tertiary interactions within the...
Tang, Roderick S., Draper, David E.
In a phasing experiment, two bends are introduced into a long duplex RNA or DNA and the number of base pairs between them varied. When electrophoresed in a gel, the set of molecules may show a...
Effective seminary presidents / (1988)
Thesis (Ph. D.)--Bowling Green State University, 1988.
Effective seminary presidents / (1988)
Thesis (Ph. D.)--Bowling Green State University, 1988.
Effective seminary presidents [microform] / (1988)
Thesis (Ph. D.)--Bowling Green State University, 1988.
White, Susan A., Draper, David E.
A set of four RNA hairpin helices has been prepared by in vitro transcription with T7 RNA polymcrase. The hairpins all contain the same nine base pair helix, but with an extra A, C, or U residue...
Bisulfite catalyzes transamination of cytidine at the N4 position; the suitability of this reaction for attaching reporter groups to selected cytidine residues in RNA molecules has been investigated....
A thermodynamic framework for Mg2+ binding to RNA
Misra, Vinod K., Draper, David E.
We present a model describing how Mg2+ binds and stabilizes specific RNA structures. In this model, RNA stabilization arises from two energetically distinct modes of Mg2+ binding: diffuse- and...
Blyn, Lawrence B., Risen, Lisa M., Griffey, Richard H., Draper, David E.
Antibiotics that inhibit ribosomal function may do so by one of several mechanisms, including the induction of incorrect RNA folding or prevention of protein and/or RNA conformational transitions....
A guide to ions and RNA structure
RNA folding into stable tertiary structures is remarkably sensitive to the concentrations and types of cations present; an understanding of the physical basis of ion-RNA interactions is therefore a...
A thermodynamic framework for Mg2+ binding to RNA
Misra, Vinod K., Draper, David E.
We present a model describing how Mg2+ binds and stabilizes specific RNA structures. In this model, RNA stabilization arises from two energetically distinct modes of Mg2+ binding: diffuse- and...
Blyn, Lawrence B., Risen, Lisa M., Griffey, Richard H., Draper, David E.
Antibiotics that inhibit ribosomal function may do so by one of several mechanisms, including the induction of incorrect RNA folding or prevention of protein and/or RNA conformational transitions....
A guide to ions and RNA structure
RNA folding into stable tertiary structures is remarkably sensitive to the concentrations and types of cations present; an understanding of the physical basis of ion-RNA interactions is therefore a...
Mg2+–RNA interaction free energies and their relationship to the folding of RNA tertiary structures
Grilley, Dan, Soto, Ana Maria, Draper, David E.
Mg2+ ions are very effective at stabilizing tertiary structures in RNAs. In most cases, folding of an RNA is so strongly coupled to its interactions with Mg2+ that it is difficult to separate free...