David J. P. Ferguson

Details der Publikationsliste

Zeitraum

1999 - 2009

Anzahl

23

Co-Autoren

Toxoplasmagondii   : 1908-2008, homage to Nicolle, Manceaux and Splendore (2009)

Ferguson, David J.P.

The discovery of Toxoplasmagondii   independently by Nicolle and Manceaux (1908) and Splendore (1908) was to open a “Pandora’s Box” that has led research on this parasite into a number of...

Oocyst wall formation and composition in coccidian parasites (2009)

Mai, Kelly, Sharman, Philippa A., Walker, Robert A., Katrib, Marilyn, De Souza, David, McConville, Malcolm J., ...

The oocyst wall of coccidian parasites is a robust structure that is resistant to a variety of environmental and chemical insults. This resilience allows oocysts to survive for long periods,...

Platelet-mediated clumping of Plasmodium falciparum-infected erythrocytes is a common adhesive phenotype and is associated with severe malaria

Pain, Arnab, Ferguson, David J. P., Kai, Oscar, Urban, Britta C., Lowe, Brett, Marsh, Kevin, ...

Sequestration of malaria-infected erythrocytes in the peripheral circulation has been associated with the virulence of Plasmodium falciparum. Defining the adhesive phenotypes of infected erythrocytes...

Developmental Expression of a Tandemly Repeated, Glycine- and Serine-Rich Spore Wall Protein in the Microsporidian Pathogen Encephalitozoon cuniculi

Bohne, Wolfgang, Ferguson, David J. P., Kohler, Karoline, Gross, Uwe

Microsporidia are intracellular organisms of increasing importance as opportunistic pathogens in immunocompromised patients. Host cells are infected by the extrusion and injection of polar tubes...

Partially Protective Vaccination Permits the Development of Latency in a Normally Virulent Strain of Toxoplasma gondii

Yap, George S., Scharton-Kersten, Tanya, Ferguson, David J. P., Howe, Dan, Suzuki, Yasuhiro, Sher, Alan

The virulent RH strain of Toxoplasma gondii is acutely lethal in mice and fails to establish chronic infection. Vaccination of BALB/c mice with a soluble tachyzoite antigen preparation, STAg, in...

Maternal Inheritance and Stage-Specific Variation of the Apicoplast in Toxoplasma gondii during Development in the Intermediate and Definitive Host

Ferguson, David J. P., Henriquez, Fiona L., Kirisits, Michael J., Muench, Stephen P., Prigge, Sean T., Rice, David W., ...

The structure and location of Toxoplasma gondii apicoplasts were examined in intermediate and definitive hosts and shown to vary in a stage-specific manner. Immunocytochemistry and electron...

Genesis of and Trafficking to the Maurer's Clefts of Plasmodium falciparum-Infected Erythrocytes†

Spycher, Cornelia, Rug, Melanie, Klonis, Nectarios, Ferguson, David J. P., Cowman, Alan F., Beck, Hans-Peter, ...

Malaria parasites export proteins beyond their own plasma membrane to locations in the red blood cells in which they reside. Maurer's clefts are parasite-derived structures within the host cell...

Platelet-mediated clumping of Plasmodium falciparum-infected erythrocytes is a common adhesive phenotype and is associated with severe malaria

Pain, Arnab, Ferguson, David J. P., Kai, Oscar, Urban, Britta C., Lowe, Brett, Marsh, Kevin, ...

Sequestration of malaria-infected erythrocytes in the peripheral circulation has been associated with the virulence of Plasmodium falciparum. Defining the adhesive phenotypes of infected erythrocytes...

Developmental Expression of a Tandemly Repeated, Glycine- and Serine-Rich Spore Wall Protein in the Microsporidian Pathogen Encephalitozoon cuniculi

Bohne, Wolfgang, Ferguson, David J. P., Kohler, Karoline, Gross, Uwe

Microsporidia are intracellular organisms of increasing importance as opportunistic pathogens in immunocompromised patients. Host cells are infected by the extrusion and injection of polar tubes...

Partially Protective Vaccination Permits the Development of Latency in a Normally Virulent Strain of Toxoplasma gondii

Yap, George S., Scharton-Kersten, Tanya, Ferguson, David J. P., Howe, Dan, Suzuki, Yasuhiro, Sher, Alan

The virulent RH strain of Toxoplasma gondii is acutely lethal in mice and fails to establish chronic infection. Vaccination of BALB/c mice with a soluble tachyzoite antigen preparation, STAg, in...

Maternal Inheritance and Stage-Specific Variation of the Apicoplast in Toxoplasma gondii during Development in the Intermediate and Definitive Host

Ferguson, David J. P., Henriquez, Fiona L., Kirisits, Michael J., Muench, Stephen P., Prigge, Sean T., Rice, David W., ...

The structure and location of Toxoplasma gondii apicoplasts were examined in intermediate and definitive hosts and shown to vary in a stage-specific manner. Immunocytochemistry and electron...

Genesis of and Trafficking to the Maurer's Clefts of Plasmodium falciparum-Infected Erythrocytes†

Spycher, Cornelia, Rug, Melanie, Klonis, Nectarios, Ferguson, David J. P., Cowman, Alan F., Beck, Hans-Peter, ...

Malaria parasites export proteins beyond their own plasma membrane to locations in the red blood cells in which they reside. Maurer's clefts are parasite-derived structures within the host cell...

Novel Type IV Secretion System Involved in Propagation of Genomic Islands▿

Juhas, Mario, Crook, Derrick W., Dimopoulou, Ioanna D., Lunter, Gerton, Harding, Rosalind M., Ferguson, David J. P., ...

Type IV secretion systems (T4SSs) mediate horizontal gene transfer, thus contributing to genome plasticity, evolution of infectious pathogens, and dissemination of antibiotic resistance and other...

Carbohydrate Metabolism in the Toxoplasma gondii Apicoplast: Localization of Three Glycolytic Isoenzymes, the Single Pyruvate Dehydrogenase Complex, and a Plastid Phosphate Translocator▿ †

Fleige, Tobias, Fischer, Karsten, Ferguson, David J. P., Gross, Uwe, Bohne, Wolfgang

Many apicomplexan parasites, such as Toxoplasma gondii and Plasmodium species, possess a nonphotosynthetic plastid, referred to as the apicoplast, which is essential for the parasites’ viability...

Vacuolar and plasma membrane stripping and autophagic elimination of Toxoplasma gondii in primed effector macrophages

Ling, Yun M., Shaw, Michael H., Ayala, Carol, Coppens, Isabelle, Taylor, Gregory A., Ferguson, David J.P., ...

Apicomplexan protozoan pathogens avoid destruction and establish a replicative niche within host cells by forming a nonfusogenic parasitophorous vacuole (PV). Here we present evidence for...

Identification of CD22 Ligands on Bone Marrow Sinusoidal Endothelium Implicated in CD22-dependent Homing of Recirculating B Cells

Nitschke, Lars, Floyd, Helen, Ferguson, David J.P., Crocker, Paul R.

CD22 is a B cell–specific transmembrane protein known to function as a negative regulator of B cell signaling. It has also been implicated in cell adhesion through recognition of α2,6-linked...

MORN1 Has a Conserved Role in Asexual and Sexual Development across the Apicomplexa▿

Ferguson, David J. P., Sahoo, Nivedita, Pinches, Robert A., Bumstead, Janene M., Tomley, Fiona M., Gubbels, Marc-Jan

The gene encoding the membrane occupation and recognition nexus protein MORN1 is conserved across the Apicomplexa. In Toxoplasma gondii, MORN1 is associated with the spindle poles, the anterior and...

Detection of Genetic Alterations by ImmunoFISH Analysis of Whole Cells Extracted from Routine Biopsy Material

Mattsson, Göran, Tan, Soo Yong, Ferguson, David J.P., Erber, Wendy, Turner, Susan H., Marafioti, Teresa, ...

The detection of genetic abnormalities (eg, translocations, amplifications) in paraffin-embedded samples by the fluorescence in situ hybridization (FISH) technique is usually performed on tissue...

Rab11A-Controlled Assembly of the Inner Membrane Complex Is Required for Completion of Apicomplexan Cytokinesis

Agop-Nersesian, Carolina, Naissant, Bernina, Rached, Fathia Ben, Rauch, Manuel, Kretzschmar, Angelika, Thiberge, Sabine, ...

The final step during cell division is the separation of daughter cells, a process that requires the coordinated delivery and assembly of new membrane to the cleavage furrow. While most eukaryotic...

Conservation of proteins involved in oocyst wall formation in Eimeria maxima, Eimeria tenella and Eimeria acervulina

Belli, Sabina I., Ferguson, David J.P., Katrib, Marilyn, Slapetova, Iveta, Mai, Kelly, Slapeta, Jan, ...

Vaccination with proteins from gametocytes of Eimeria maxima protects chickens, via transfer of maternal antibodies, against infection with several species of Eimeria. Antibodies to E. maxima...