David M. Bannerman

Enhanced long-term and impaired short-term spatial memory in GluA1 AMPA receptor subunit knockout mice: Evidence for a dual-process memory model (2009)

Sanderson, David J., Good, Mark A., Skelton, Kathryn, Sprengel, Rolf, Seeburg, Peter H., Rawlins, J. Nicholas P., ...

The GluA1 AMPA receptor subunit is a key mediator of hippocampal synaptic plasticity and is especially important for a rapidly-induced, short-lasting form of potentiation. GluA1 gene deletion impairs...

Behavioural characterization of neuregulin 1 type I overexpressing transgenic mice (2009)

Deakin, Inga H., Law, Amanda J., Oliver, Peter L., Schwab, Markus H., Nave, Klaus-Armin, Harrison, Paul J., ...

Behavioral/Systems/Cognitive The Role of Hippocampal Glutamate Receptor-A-Dependent Synaptic Plasticity in Conditional Learning: The Importance (2008)

Of Spatiotemporal Discontiguity, Wolfram B. Schmitt, Roozbeh Arianpour, Robert M. J. Deacon, Peter H. Seeburg, Rolf Sprengel, ...

Gene-targeted mice lacking the AMPA receptor subunit glutamate receptor-A (GluR-A or GluR1) and mice with cytotoxic hippocampal lesions were compared with wild-type and sham-operated controls,...

NMDA receptor subunit NR2A is required for rapidly acquired spatial working memory but not incremental spatial reference memory (2008)

Bannerman, David M., Niewoehner, Burkhard, Lyon, Louisa, Romberg, Carola, Schmitt, Wolfram B., Taylor, Amy, ...

NMDA receptors (NMDARs) containing NR2A ({varepsilon}1) subunits are key contributors to hippocampal long−term potentiation (LTP) induction in adult animals and have therefore been widely...

Contribution of Hippocampal and Extra−Hippocampal NR2B−Containing NMDA Receptors to Performance on Spatial Learning Tasks (2008)

Von Engelhardt, Jakob, Doganci, Beril, Jensen, Vidar, Hvalby, Øivind, Göngrich, Christina, Taylor, Amy, ...

Controversy revolves around the differential contribution of NR2A− and NR2B−containing NMDA receptors, which coexist in principal forebrain neurons, to synaptic plasticity and learning in the...

Remembering the subtle differences (2007)

Bannerman, David M., Sprengel, Rolf

A good taxi driver in a cosmopolitan city has to find an arbitrary destination from any starting point, efficiently and with high precision, relying on recollection of the city's layout and...

Separate neural pathways process different decision costs (2006)

Peter H Rudebeck, Mark E Walton, Angharad N Smyth, David M Bannerman, Matthew F S Rushworth

Restoration of spatial working memory by genetic rescue of GluR−A−deficient mice (2005)

Schmitt, W., Sprengel, Rolf, Mack, Volker, Draft, Ryan, Seeburg, Peter H., Deacon, Robert M. J., ...

Gene−targeted mice lacking the AMPA receptor subunit GluR−A (also called GluR1 encoded by the gene Gria1,) have deficits in hippocampal CA3−CA1 long−term potentiation (LTP) and have...

The role of hippocampal glutamate receptor−A−dependent synaptic plasticity in conditional learning: the importance of spatio−temporal discontiguity (2004)

Schmitt,Wolfram B., Arianpour,Roozbeh, Deacon,Robert M. J., Seeburg,Peter H., Sprengel,Rolf, Rawlins,J. Nicholas P., ...

Gene−targeted mice lacking the AMPA receptor subunit glutamate receptor−A (GluR−A or GluR1) and mice with cytotoxic hippocampal lesions were compared with wild−type and sham−operated...

A comparison of GluR−A−deficient and wild−type mice on a test battery assessing sensorimotor, affective, and cognitive behaviors (2004)

Bannerman,David M., Deacon,Robert M. J., Brady,S., Bruce,A., Sprengel,Rolf, Seeburg,Peter H., ...

Previous studies have demonstrated a spatial working memory deficit in glutamate receptor (GluR)−A (GluR1) AMPA receptor subunit knockout mice. The present study evaluated male and female...

A comparison of GluR−A−deficient and wild−type mice on a test battery assessing sensorimotor, affective, and cognitive behaviors (2004)

Bannerman, David M., Deacon, Robert M. J., Brady, S., Bruce, A., Sprengel, Rolf, Seeburg, Peter H., ...

Previous studies have demonstrated a spatial working memory deficit in glutamate receptor (GluR)−A (GluR1) AMPA receptor subunit knockout mice. The present study evaluated male and female...

The role of hippocampal glutamate receptor−A−dependent synaptic plasticity in conditional learning: the importance of spatio−temporal discontiguity (2004)

Schmitt, Wolfram B., Arianpour, Roozbeh, Deacon, Robert M. J., Seeburg, Peter H., Sprengel, Rolf, Rawlins, J. Nicholas P., ...

Gene−targeted mice lacking the AMPA receptor subunit glutamate receptor−A (GluR−A or GluR1) and mice with cytotoxic hippocampal lesions were compared with wild−type and sham−operated...

GluR-A-deficient mice display normal acquisition of a hippocampus-dependent spatial reference memory task but are impaired during spatial reversal (2003)

Bannerman,David M., Deacon,Robert M. J., Seeburg,Peter H., Rawlins,J. Nicholas P.

Acquisition and reversal of a spatial discrimination were assessed in an appetitive, elevated plus-maze task in 4 groups of mice: knockout mice lacking the AMPA receptor subunit GluR-A (GluR1),...

A Within-Subjects, Within-Task Demonstration of Intact Spatial Reference Memory and Impaired Spatial Working Memory in Glutamate Receptor-A-Deficient Mice (2003)

Schmitt,Wolfram B., Deacon,Robert M. J., Seeburg,Peter H., Rawlins,J. Nicholas P., Bannerman,David M.

Gene-targeted mice lacking the AMPA receptor subunit glutamate receptor-A (GluRA) (GluR1) and wild-type controls were compared on a radial-maze task in which the same three of six arms were always...

A Within-Subjects, Within-Task Demonstration of Intact Spatial Reference Memory and Impaired Spatial Working Memory in Glutamate Receptor-A-Deficient Mice (2003)

Schmitt, Wolfram B., Deacon, Robert M. J., Seeburg, Peter H., Rawlins, J. Nicholas P., Bannerman, David M.

Gene-targeted mice lacking the AMPA receptor subunit glutamate receptor-A (GluRA) (GluR1) and wild-type controls were compared on a radial-maze task in which the same three of six arms were always...

GluR-A-deficient mice display normal acquisition of a hippocampus-dependent spatial reference memory task but are impaired during spatial reversal (2003)

Bannerman, David M., Deacon, Robert M. J., Seeburg, Peter H., Rawlins, J. Nicholas P.

Acquisition and reversal of a spatial discrimination were assessed in an appetitive, elevated plus-maze task in 4 groups of mice: knockout mice lacking the AMPA receptor subunit GluR-A (GluR1),...

Spatial memory dissociations in mice lacking GluR1 (2002)

Reisel,D., Bannerman,David M., Schmitt,W. B., Deacon,Robert M. J., Flint,J., Borchardt,Thilo, ...

Gene-targeted mice lacking the AMPA receptor subunit GluR1 (GluR-A) have deficits in hippocampal CA3–CA1 long-term potentiation. We now report that they showed normal spatial reference learning and...

Spatial memory dissociations in mice lacking GluR1 (2002)

Reisel, D., Bannerman, David M., Schmitt, W. B., Deacon, Robert M. J., Flint, J., Borchardt, Thilo, ...

Gene-targeted mice lacking the AMPA receptor subunit GluR1 (GluR-A) have deficits in hippocampal CA3–CA1 long-term potentiation. We now report that they showed normal spatial reference learning and...

Dorsal hippocampal N-methyl-d-aspartate receptors underlie spatial working memory performance during non-matching to place testing on the T-maze

McHugh, Stephen B., Niewoehner, Burkhard, Rawlins, J.N.P., Bannerman, David M.

Previous lesion studies have suggested a functional dissociation along the septotemporal axis of the hippocampus. Whereas the dorsal hippocampus has been implicated in spatial memory processes, the...

Distinct contributions of frontal areas to emotion and social behaviour in the rat

Rudebeck, Peter H, Walton, Mark E, Millette, Benjamin H P, Shirley, Elizabeth, Rushworth, Matthew F S, Bannerman, David M

Although the lesions of patients with impaired social behaviour encompass both orbitofrontal and anterior cingulate cortex (OFC and ACC), attempts to model such impairments in animals have focused on...

Induction and expression of GluA1 (GluR-A)-independent LTP in the hippocampus

Romberg, Carola, Raffel, Joel, Martin, Lucy, Sprengel, Rolf, Seeburg, Peter H, Rawlins, J Nicholas P, ...

Long-term potentiation (LTP) at hippocampal CA3–CA1 synapses is thought to be mediated, at least in part, by an increase in the postsynaptic surface expression of...

Enhanced long-term and impaired short-term spatial memory in GluA1 AMPA receptor subunit knockout mice: Evidence for a dual-process memory model

Sanderson, David J., Good, Mark A., Skelton, Kathryn, Sprengel, Rolf, Seeburg, Peter H., Rawlins, J. Nicholas P., ...

The GluA1 AMPA receptor subunit is a key mediator of hippocampal synaptic plasticity and is especially important for a rapidly-induced, short-lasting form of potentiation. GluA1 gene deletion impairs...

Hippocampal NMDA receptors and anxiety: At the interface between cognition and emotion

Barkus, Christopher, McHugh, Stephen B., Sprengel, Rolf, Seeburg, Peter H., Rawlins, J. Nicholas P., Bannerman, David M.

David De Wied had a fundamental interest in the brain and behaviour, with a particular interest in the interface between cognition and emotion, and how impairments at this interface could underlie...