David Serre, Scott Gurd, Bing Ge, Robert Sladek, Donna Sinnett, Eef Harmsen, ...
The recent development of whole genome association studies has lead to the robust identification of several loci involved in different common human diseases. Interestingly, some of the strongest...
Heritability of alternative splicing in the human genome (2007)
Kwan, Tony, Benovoy, David, Dias, Christel, Gurd, Scott, Serre, David, Zuzan, Harry, ...
Alternative pre-mRNA splicing increases proteomic diversity and provides a potential mechanism underlying both phenotypic diversity and susceptibility to genetic disorders in human populations. To...
Neanderthals in central Asia and Siberia (2007)
Krause, Johannes, Orlando, Ludivic, Serre, David, Bence, Viola, Prüfer, Kay, Richards, Michael P., ...
No evidence of Neanderthal mtDNA contribution to early modern humans (2006)
Serre, David, Langaney, A., Chech, M., Teschler-Nicola, M., Paunovic, M., Mennecier, P., ...
Nuclear insertions help and hinder inference of the evolutionary history of gorilla mtDNA (2005)
Thalmann, Olaf, Serre, David, Hofreiter, Michael, Lukas, Dieter, Eriksson, Jonas, Vigilant, Linda
Large-scale recombination rate patterns are conserved among human populations (2005)
Serre, David, Nadon, Robert, Hudson, Thomas J.
In humans, most recombination events occur in a small fraction of the genome. These hotspots of recombination show considerable variation in intensity and/or location across species and, potentially,...
A late Neandertal femur from Les Rochers-de-Villeneuve, France (2005)
Beauval, Cédric, Maureille, Bruno, Lacrampe-Cuyaubère, François, Serre, David, Peressinotto, David, Bordes, Jean-Guillaume, ...
In 2002, a Neandertal partial femoral diaphysis was discovered at Les Rochers-de-Villeneuve (Vienne, France). Radiocarbon dated to +/- 40,700 14C years before present, this specimen is one of the...
A late Neandertal femur from Les Rochers-de-Villeneuve, France (2005)
Beauval, Cédric, Maureille, Bruno, Lacrampe-Cuyaubère, François, Serre, David, Peressinotto, David, Bordes, Jean-Guillaume, ...
In 2002, a Neandertal partial femoral diaphysis was discovered at Les Rochers-de-Villeneuve (Vienne, France). Radiocarbon dated to +/- 40,700 14C years before present, this specimen is one of the...
No Evidence of Neandertal mtDNA Contribution to Early Modern Humans (2004)
David Serre, André Langaney, Mario Chech, Maria Teschler-Nicola, Maja Paunovic, Philippe Mennecier, ...
Analysis of mitochondrial DNA from four Neandertal fossils and five "modern human" contemporaries excludes any large genetic contribution of Neandertals to the gene pool of modern humans.
No Evidence of Neandertal mtDNA Contribution to Early Modern Humans (2004)
David Serre, André Langaney, Mario Chech, Maria Teschler-Nicola, Maja Paunovic, Philippe Mennecier, ...
The retrieval of mitochondrial DNA (mtDNA) sequences from four Neandertal fossils from Germany, Russia, and Croatia has demonstrated that these individuals carried closely related mtDNAs that are not...
Lack of phylogeography in European mammals before the last glaciation (2004)
Hofreiter, Michael, Serre, David, Nadin, Rohland, Rabeder, Gernot, Nagel, Doris, Conard, Nicholas, ...
Genetic analyses from ancient DNA (2004)
Pääbo, Svante, Poinar, Hendrik, Serre, David, Jaenicke-Després, Viviane, Hebler, Juliane, Rohland, Nadin, ...
No evidence of Neandertal mtDNA contribution to early modern humans (2004)
Serre, David, Langaney, A., Chell, M., Teschler-Nicola, M., Paunovic, M., Mennecier, P., ...
The retrieval of mitochondrial DNA (mtDNA) sequences from four Neandertal fossils from Germany, Russia, and Croatia has demonstrated that these individuals carried closely related mtDNAs that are not...
Schmitz, R. W., Serre, David, Bonani, G., Feine, S., Hillgruber, F., Krainitzki, H., ...
The 1856 discovery of the Neandertal type specimen (Neandertal 1) in western Germany marked the beginning of human paleontology and initiated the longest-standing debate in the discipline: the role...
Hofreiter, Michael, Jaenicke, Viviane, Serre, David, Haeseler, Arndt Von, Pääbo, Svante
We show that DNA molecules amplified by PCR from DNA extracted from animal bones and teeth that vary in age between 25 000 and over 50 000 years carry C→T and G→A substitutions. These...
Schmitz, Ralf W., Serre, David, Bonani, Georges, Feine, Susanne, Hillgruber, Felix, Krainitzki, Heike, ...
The 1856 discovery of the Neandertal type specimen (Neandertal 1) in western Germany marked the beginning of human paleontology and initiated the longest-standing debate in the discipline: the role...
No Evidence of Neandertal mtDNA Contribution to Early Modern Humans
Serre, David, Langaney, André, Chech, Mario, Teschler-Nicola, Maria, Paunovic, Maja, Mennecier, Philippe, ...
The retrieval of mitochondrial DNA (mtDNA) sequences from four Neandertal fossils from Germany, Russia, and Croatia has demonstrated that these individuals carried closely related mtDNAs that are not...
Evidence for Gradients of Human Genetic Diversity Within and Among Continents
Genetic variation in humans is sometimes described as being discontinuous among continents or among groups of individuals, and by some this has been interpreted as genetic support for “races.” A...
Lack of phylogeography in European mammals before the last glaciation
Hofreiter, Michael, Serre, David, Rohland, Nadin, Rabeder, Gernot, Nagel, Doris, Conard, Nicholas, ...
In many extant animal and plant species in Europe and North America a correlation exists between the geographical location of individuals and the genetic relatedness of the mitochondrial (mt) DNA...
A late Neandertal femur from Les Rochers-de-Villeneuve, France
Beauval, Cédric, Maureille, Bruno, Lacrampe-Cuyaubère, François, Serre, David, Peressinotto, David, Bordes, Jean-Guillaume, ...
In 2002, a Neandertal partial femoral diaphysis was discovered at Les Rochers-de-Villeneuve (Vienne, France). Radiocarbon dated to ≈40,700 14C years before present, this specimen is one of the most...
Large-scale recombination rate patterns are conserved among human populations
Serre, David, Nadon, Robert, Hudson, Thomas J.
In humans, most recombination events occur in a small fraction of the genome. These hotspots of recombination show considerable variation in intensity and/or location across species and, potentially,...
Hofreiter, Michael, Jaenicke, Viviane, Serre, David, Haeseler, Arndt Von, Pääbo, Svante
We show that DNA molecules amplified by PCR from DNA extracted from animal bones and teeth that vary in age between 25 000 and over 50 000 years carry C→T and G→A substitutions. These...
Schmitz, Ralf W., Serre, David, Bonani, Georges, Feine, Susanne, Hillgruber, Felix, Krainitzki, Heike, ...
The 1856 discovery of the Neandertal type specimen (Neandertal 1) in western Germany marked the beginning of human paleontology and initiated the longest-standing debate in the discipline: the role...
No Evidence of Neandertal mtDNA Contribution to Early Modern Humans
Serre, David, Langaney, André, Chech, Mario, Teschler-Nicola, Maria, Paunovic, Maja, Mennecier, Philippe, ...
The retrieval of mitochondrial DNA (mtDNA) sequences from four Neandertal fossils from Germany, Russia, and Croatia has demonstrated that these individuals carried closely related mtDNAs that are not...
Evidence for Gradients of Human Genetic Diversity Within and Among Continents
Genetic variation in humans is sometimes described as being discontinuous among continents or among groups of individuals, and by some this has been interpreted as genetic support for “races.” A...
Lack of phylogeography in European mammals before the last glaciation
Hofreiter, Michael, Serre, David, Rohland, Nadin, Rabeder, Gernot, Nagel, Doris, Conard, Nicholas, ...
In many extant animal and plant species in Europe and North America a correlation exists between the geographical location of individuals and the genetic relatedness of the mitochondrial (mt) DNA...
A late Neandertal femur from Les Rochers-de-Villeneuve, France
Beauval, Cédric, Maureille, Bruno, Lacrampe-Cuyaubère, François, Serre, David, Peressinotto, David, Bordes, Jean-Guillaume, ...
In 2002, a Neandertal partial femoral diaphysis was discovered at Les Rochers-de-Villeneuve (Vienne, France). Radiocarbon dated to ≈40,700 14C years before present, this specimen is one of the most...
Large-scale recombination rate patterns are conserved among human populations
Serre, David, Nadon, Robert, Hudson, Thomas J.
In humans, most recombination events occur in a small fraction of the genome. These hotspots of recombination show considerable variation in intensity and/or location across species and, potentially,...
Paré, Guillaume, Serre, David, Brisson, Diane, Anand, Sonia S., Montpetit, Alexandre, Tremblay, Gérald, ...
Coronary artery disease (CAD) is a major health concern in both developed and developing countries. With a heritability estimated at ∼50%, there is a strong rationale to better define the genetic...
Heritability of alternative splicing in the human genome
Kwan, Tony, Benovoy, David, Dias, Christel, Gurd, Scott, Serre, David, Zuzan, Harry, ...
Alternative pre-mRNA splicing increases proteomic diversity and provides a potential mechanism underlying both phenotypic diversity and susceptibility to genetic disorders in human populations. To...
Correction of Population Stratification in Large Multi-Ethnic Association Studies
Serre, David, Montpetit, Alexandre, Paré, Guillaume, Engert, James C., Yusuf, Salim, Keavney, Bernard, ...
Serre, David, Gurd, Scott, Ge, Bing, Sladek, Robert, Sinnett, Donna, Harmsen, Eef, ...
The recent development of whole genome association studies has lead to the robust identification of several loci involved in different common human diseases. Interestingly, some of the strongest...