Exact model reduction of combinatorial reaction networks (2008)
Conzelmann, Holger, Fey, Dirk, Gilles, Ernst D
Abstract Background Receptors and scaffold proteins usually possess a high number of distinct binding domains inducing the formation of large multiprotein signaling complexes. Due to combinatorial...
Multi-scale modeling of angiotensin II induced neuronal regulatory mechanisms in the brain (2008)
Vadigepalli, Rajanikanth, Fey, Dirk, Schwaber, James S
No abstract available.
Identifikation biochemischer Reaktionsnetzwerke: Ein beobachterbasierter Ansatz (2008)
Bullinger, Eric, Fey, Dirk, Farina, Marcello, Findeisen, Rolf
Dynamic models present a fundamental tool in systems biology, but rely on kinetic parameters, such as association and dissociation constants. Their direct estimation from studies on isolated...