Dirk Fey

Exact model reduction of combinatorial reaction networks (2008)

Conzelmann, Holger, Fey, Dirk, Gilles, Ernst D

Abstract Background Receptors and scaffold proteins usually possess a high number of distinct binding domains inducing the formation of large multiprotein signaling complexes. Due to combinatorial...

Identifikation biochemischer Reaktionsnetzwerke: Ein beobachterbasierter Ansatz (2008)

Bullinger, Eric, Fey, Dirk, Farina, Marcello, Findeisen, Rolf

Dynamic models present a fundamental tool in systems biology, but rely on kinetic parameters, such as association and dissociation constants. Their direct estimation from studies on isolated...