Dominique Soldati

Toxoplasma gondii myosin A and its light chain: a fast, single-headed, plusend directed motor (2002)

Herm-Götz,Angelika, Weiss,Stefan, Stratmann,Rolf, Fujita-Becker,Setsuko, Ruff,Christine, Meyhöfer,Edgar, ...

Successful host cell invasion is a prerequisite for survival of the obligate intracellular apicomplexan parasites and establishment of infection. Toxoplasma gondii penetrates host cells by an active...

Toxoplasma gondii myosin A and its light chain: a fast, single-headed, plusend directed motor (2002)

Herm-Götz,Angelika, Weiss,Stefan, Stratmann,Rolf, Fujita-Becker,Setsuko, Ruff,Christine, Meyhöfer,Edgar, ...

Successful host cell invasion is a prerequisite for survival of the obligate intracellular apicomplexan parasites and establishment of infection. Toxoplasma gondii penetrates host cells by an active...

Toxoplasma gondii myosin A and its light chain: a fast, single-headed, plusend directed motor (2002)

Herm-Götz, Angelika, Weiss, Stefan, Stratmann, Rolf, Fujita-Becker, Setsuko, Ruff, Christine, Meyhöfer, Edgar, ...

Successful host cell invasion is a prerequisite for survival of the obligate intracellular apicomplexan parasites and establishment of infection. Toxoplasma gondii penetrates host cells by an active...

Toxoplasma gondii myosin A and its light chain: a fast, single-headed, plusend directed motor (2002)

Herm-Götz, Angelika, Weiss, Stefan, Stratmann, Rolf, Fujita-Becker, Setsuko, Ruff, Christine, Meyhöfer, Edgar, ...

Successful host cell invasion is a prerequisite for survival of the obligate intracellular apicomplexan parasites and establishment of infection. Toxoplasma gondii penetrates host cells by an active...

Toxoplasma gondii myosins B/C: one gene, two tails, two localizations and a role in parasite division (2001)

Delbac,Frédéric, Sänger,Astrid, Neuhaus,Eva M., Stratmann,Rolf, Ajioka,James W., Toursel,Catherine, ...

In apicomplexan parasites, actin-disrupting drugs and the inhibitor of myosin heavy chain ATPase, 2,3-butanedione monoxime, have been shown to interfere with host cell invasion by inhibiting parasite...

Toxoplasma gondii myosins B/C: one gene, two tails, two localizations and a role in parasite division (2001)

Delbac,Frédéric, Sänger,Astrid, Neuhaus,Eva M., Stratmann,Rolf, Ajioka,James W., Toursel,Catherine, ...

In apicomplexan parasites, actin-disrupting drugs and the inhibitor of myosin heavy chain ATPase, 2,3-butanedione monoxime, have been shown to interfere with host cell invasion by inhibiting parasite...

Toxoplasma gondii myosins B/C: one gene, two tails, two localizations and a role in parasite division (2001)

Delbac, Frédéric, Sänger, Astrid, Neuhaus, Eva M., Stratmann, Rolf, Ajioka, James W., Toursel, Catherine, ...

In apicomplexan parasites, actin-disrupting drugs and the inhibitor of myosin heavy chain ATPase, 2,3-butanedione monoxime, have been shown to interfere with host cell invasion by inhibiting parasite...

Toxoplasma gondii myosins B/C: one gene, two tails, two localizations and a role in parasite division (2001)

Delbac, Frédéric, Sänger, Astrid, Neuhaus, Eva M., Stratmann, Rolf, Ajioka, James W., Toursel, Catherine, ...

In apicomplexan parasites, actin-disrupting drugs and the inhibitor of myosin heavy chain ATPase, 2,3-butanedione monoxime, have been shown to interfere with host cell invasion by inhibiting parasite...

Modulation of myosin A expression by a newly established tetracycline repressor-based inducible system in Toxoplasma gondii (2001)

Meissner, Markus, Brecht, Susan, Bujard, Hermann, Soldati, Dominique

We have developed a control system for regulating gene activation in Toxoplasma gondii. The elements of this system are derived from the Escherichia coli tetracycline resistance operon, which has...

A dibasic motif in the tail of a class XIV apicomplexan myosin is an essential determinant of plasma membrane localization (2000)

Hettmann,Christine, Herm,Angelika, Geiter,Ariane, Frank,Bernd, Schwarz,Eva C., Soldati,Thierry, ...

Obligate intracellular parasites of the phylum Apicomplexa exhibit gliding motility, a unique form of substrate-dependent locomotion essential for host cell invasion and shown to involve the parasite...

A dibasic motif in the tail of a class XIV apicomplexan myosin is an essential determinant of plasma membrane localization (2000)

Hettmann,Christine, Herm,Angelika, Geiter,Ariane, Frank,Bernd, Schwarz,Eva C., Soldati,Thierry, ...

Obligate intracellular parasites of the phylum Apicomplexa exhibit gliding motility, a unique form of substrate-dependent locomotion essential for host cell invasion and shown to involve the parasite...

A dibasic motif in the tail of a class XIV apicomplexan myosin is an essential determinant of plasma membrane localization (2000)

Hettmann, Christine, Herm, Angelika, Geiter, Ariane, Frank, Bernd, Schwarz, Eva C., Soldati, Thierry, ...

Obligate intracellular parasites of the phylum Apicomplexa exhibit gliding motility, a unique form of substrate-dependent locomotion essential for host cell invasion and shown to involve the parasite...

A dibasic motif in the tail of a class XIV apicomplexan myosin is an essential determinant of plasma membrane localization (2000)

Hettmann, Christine, Herm, Angelika, Geiter, Ariane, Frank, Bernd, Schwarz, Eva C., Soldati, Thierry, ...

Obligate intracellular parasites of the phylum Apicomplexa exhibit gliding motility, a unique form of substrate-dependent locomotion essential for host cell invasion and shown to involve the parasite...

Variable effects of the conserved RNA hairpin element upon 3' end processing of histone pre-mRNA in vitro (1993)

Streit, Adrian, Koning, Tom Wittop, Soldati, Dominique, Melin, Lars, Schümperli, Daniel

We have studied the requirements for efficient histone-specific RNA 3′ processing in nuclear extract from mammalian tissue culture cells. Processing is strongly impaired by mutations in the...

A Dibasic Motif in the Tail of a Class XIV Apicomplexan Myosin Is an Essential Determinant of Plasma Membrane Localization

Hettmann, Christine, Herm, Angelika, Geiter, Ariane, Frank, Bernd, Schwarz, Eva, Soldati, Thierry, ...

Obligate intracellular parasites of the phylum Apicomplexa exhibit gliding motility, a unique form of substrate-dependent locomotion essential for host cell invasion and shown to involve the parasite...

Two Conserved Amino Acid Motifs Mediate Protein Targeting to the Micronemes of the Apicomplexan Parasite Toxoplasma gondii

Di Cristina, Manlio, Spaccapelo, Roberta, Soldati, Dominique, Bistoni, Francesco, Crisanti, Andrea

The micronemal protein 2 (MIC2) of Toxoplasma gondii shares sequence and structural similarities with a series of adhesive molecules of different apicomplexan parasites. These molecules accumulate,...

Modulation of myosin A expression by a newly established tetracycline repressor-based inducible system in Toxoplasma gondii

Meissner, Markus, Brecht, Susan, Bujard, Hermann, Soldati, Dominique

We have developed a control system for regulating gene activation in Toxoplasma gondii. The elements of this system are derived from the Escherichia coli tetracycline resistance operon, which has...

Transformed Toxoplasma gondii Tachyzoites Expressing the Circumsporozoite Protein of Plasmodium knowlesi Elicit a Specific Immune Response in Rhesus Monkeys

Di Cristina, Manlio, Ghouze, Firman, Kocken, Clemens H. M., Naitza, Silvia, Cellini, Pamela, Soldati, Dominique, ...

Toxoplasma gondii tachyzoites were transformed with the coding sequence of the circumsporozoite (CS) protein of the primate malaria parasite Plasmodium knowlesi. A single inoculation of live...

Intramembrane cleavage of microneme proteins at the surface of the apicomplexan parasite Toxoplasma gondii

Opitz, Corinna, Di Cristina, Manlio, Reiss, Matthias, Ruppert, Thomas, Crisanti, Andrea, Soldati, Dominique

Apicomplexan parasites actively secrete proteins at their apical pole as part of the host cell invasion process. The adhesive micronemal proteins are involved in the recognition of host cell...

Toxoplasma gondii myosin A and its light chain: a fast, single-headed, plus-end-directed motor

Herm-Götz, Angelika, Weiss, Stefan, Stratmann, Rolf, Fujita-Becker, Setsuko, Ruff, Christine, Meyhöfer, Edgar, ...

Successful host cell invasion is a prerequisite for survival of the obligate intracellular apicomplexan parasites and establishment of infection. Toxoplasma gondii penetrates host cells by an active...

Conditional Expression of Toxoplasma gondii Apical Membrane Antigen-1 (TgAMA1) Demonstrates That TgAMA1 Plays a Critical Role in Host Cell Invasion

Mital, Jeffrey, Meissner, Markus, Soldati, Dominique, Ward, Gary E.

Toxoplasma gondii is an obligate intracellular parasite and an important human pathogen. Relatively little is known about the proteins that orchestrate host cell invasion by T. gondii or related...

New insights into myosin evolution and classification

Foth, Bernardo J., Goedecke, Marc C., Soldati, Dominique

Myosins are eukaryotic actin-dependent molecular motors important for a broad range of functions like muscle contraction, vision, hearing, cell motility, and host cell invasion of apicomplexan...

A Dibasic Motif in the Tail of a Class XIV Apicomplexan Myosin Is an Essential Determinant of Plasma Membrane Localization

Hettmann, Christine, Herm, Angelika, Geiter, Ariane, Frank, Bernd, Schwarz, Eva, Soldati, Thierry, ...

Obligate intracellular parasites of the phylum Apicomplexa exhibit gliding motility, a unique form of substrate-dependent locomotion essential for host cell invasion and shown to involve the parasite...

Two Conserved Amino Acid Motifs Mediate Protein Targeting to the Micronemes of the Apicomplexan Parasite Toxoplasma gondii

Di Cristina, Manlio, Spaccapelo, Roberta, Soldati, Dominique, Bistoni, Francesco, Crisanti, Andrea

The micronemal protein 2 (MIC2) of Toxoplasma gondii shares sequence and structural similarities with a series of adhesive molecules of different apicomplexan parasites. These molecules accumulate,...

Modulation of myosin A expression by a newly established tetracycline repressor-based inducible system in Toxoplasma gondii

Meissner, Markus, Brecht, Susan, Bujard, Hermann, Soldati, Dominique

We have developed a control system for regulating gene activation in Toxoplasma gondii. The elements of this system are derived from the Escherichia coli tetracycline resistance operon, which has...

Transformed Toxoplasma gondii Tachyzoites Expressing the Circumsporozoite Protein of Plasmodium knowlesi Elicit a Specific Immune Response in Rhesus Monkeys

Di Cristina, Manlio, Ghouze, Firman, Kocken, Clemens H. M., Naitza, Silvia, Cellini, Pamela, Soldati, Dominique, ...

Toxoplasma gondii tachyzoites were transformed with the coding sequence of the circumsporozoite (CS) protein of the primate malaria parasite Plasmodium knowlesi. A single inoculation of live...

Intramembrane cleavage of microneme proteins at the surface of the apicomplexan parasite Toxoplasma gondii

Opitz, Corinna, Di Cristina, Manlio, Reiss, Matthias, Ruppert, Thomas, Crisanti, Andrea, Soldati, Dominique

Apicomplexan parasites actively secrete proteins at their apical pole as part of the host cell invasion process. The adhesive micronemal proteins are involved in the recognition of host cell...

Toxoplasma gondii myosin A and its light chain: a fast, single-headed, plus-end-directed motor

Herm-Götz, Angelika, Weiss, Stefan, Stratmann, Rolf, Fujita-Becker, Setsuko, Ruff, Christine, Meyhöfer, Edgar, ...

Successful host cell invasion is a prerequisite for survival of the obligate intracellular apicomplexan parasites and establishment of infection. Toxoplasma gondii penetrates host cells by an active...

Tetracycline analogue-regulated transgene expression in Plasmodium falciparum blood stages using Toxoplasma gondii transactivators

Meissner, Markus, Krejany, Efrosinia, Gilson, Paul R., Soldati, Dominique, Crabb, Brendan S.

Genetic manipulation has revolutionized research in the Apicomplexan parasite Plasmodium falciparum, the most important causative agent of malaria. However, to date no techniques have been...

Conditional Expression of Toxoplasma gondii Apical Membrane Antigen-1 (TgAMA1) Demonstrates That TgAMA1 Plays a Critical Role in Host Cell Invasion

Mital, Jeffrey, Meissner, Markus, Soldati, Dominique, Ward, Gary E.

Toxoplasma gondii is an obligate intracellular parasite and an important human pathogen. Relatively little is known about the proteins that orchestrate host cell invasion by T. gondii or related...

New insights into myosin evolution and classification

Foth, Bernardo J., Goedecke, Marc C., Soldati, Dominique

Myosins are eukaryotic actin-dependent molecular motors important for a broad range of functions like muscle contraction, vision, hearing, cell motility, and host cell invasion of apicomplexan...

Identification and Characterization of an Escorter for Two Secretory Adhesins in Toxoplasma gondii

Reiss, Matthias, Viebig, Nicola, Brecht, Susan, Fourmaux, Marie-Noelle, Soete, Martine, Di Cristina, Manlio, ...

The intracellular protozoan parasite Toxoplasma gondii shares with other members of the Apicomplexa a common set of apical structures involved in host cell invasion. Micronemes are apical secretory...

Toxoplasma gondii myosins B/C: one gene, two tails, two localizations, and a role in parasite division

Delbac, Frédéric, Sänger, Astrid, Neuhaus, Eva M., Stratmann, Rolf, Ajioka, James W., Toursel, Catherine, ...

In apicomplexan parasites, actin-disrupting drugs and the inhibitor of myosin heavy chain ATPase, 2,3-butanedione monoxime, have been shown to interfere with host cell invasion by inhibiting parasite...