E. Bosmans

Details der Publikationsliste

Zeitraum

1991 - 2006

Anzahl

83

Co-Autoren

Perinatal outcome of 12 021 singleton and 3108 twin births after non-IVF-assisted reproduction: a cohort study (2006)

Ombelet, W, Martens, G, De Sutter, P, Gerris, J, Bosmans, E, Ruyssinck, G, ...

Perinatal outcome of pregnancies caused by assisted reproduction technique (ART) is substantially worse when compared with pregnancies following natural conception. We investigated the possible risks...

Perinatal outcome of 12 021 singleton and 3108 twin births after non-IVF-assisted reproduction: a cohort study (2006)

Ombelet, W, Martens, G, De Sutter, P, Gerris, J, Bosmans, E, Ruyssinck, G, ...

Perinatal outcome of pregnancies caused by assisted reproduction technique (ART) is substantially worse when compared with pregnancies following natural conception. We investigated the possible risks...

Perinatal outcome of 12 021 singleton and 3108 twin births after non-IVF-assisted reproduction: a cohort study (2006)

Ombelet, W, Martens, G, De Sutter, P, Gerris, J, Bosmans, E, Ruyssinck, G, ...

Perinatal outcome of pregnancies caused by assisted reproduction technique (ART) is substantially worse when compared with pregnancies following natural conception. We investigated the possible risks...

Engineering camel single-domain antibodies and immobilization chemistry for human prostate-specific antigen sensing (2005)

Saerens, D, Frederix, Filip; U0032313, Reekmans, G, Conrath, K, Jans, K, Brys, L, ...

The specificity and affinity characteristics of antibodies make them excellent probes in biosensor applications. Unfortunately, their large size, unstable behavior, and random immobilization...

Perinatal outcome of ICSI pregnancies compared with a matched group of natural conception pregnancies in Flanders (Belgium): a cohort study (2005)

Peeraer, K, De Sutter, P, Gerris, J, Bosmans, E, Martens, G, Ruyssinck, G, ...

A retrospective cohort study was conducted with an intracytoplasmic sperm injection (ICSI) group and a naturally conceived comparison group. A total of 1655 singleton and 1102 twin ICSI births were...

Obstetric and perinatal outcome of 1655 ICSI and 3974 IVF singleton and 1102 ICSI and 2901 lVF twin births: a comparative analysis (2005)

Cadron, I, Gerris, J, De Sutter, P, Bosmans, E, Martens, G, Ruyssinck, G, ...

A total of 3974 IVF and 1655 ICSI singleton births and 2901 IVF and 1102 ICSI twin births were evaluated. Pregnancies after both fresh and frozen transfers were included. IVF and ICSI singleton...

Perinatal outcome of ICSI pregnancies compared with a matched group of natural conception pregnancies in Flanders (Belgium): a cohort study (2005)

OMBELET, Willem, Peeraer, K, De Sutter, P, Gerris, J, Bosmans, E, Martens, G, ...

A retrospective cohort study was conducted with an intracytoplasmic sperm injection (ICSI) group and a naturally conceived comparison group. A total of 1655 singleton and 1102 twin ICSI births were...

Obstetric and perinatal outcome of 1655 ICSI and 3974 IVF singleton and 1102 ICSI and 2901 lVF twin births: a comparative analysis (2005)

OMBELET, Willem, Cadron, I, Gerris, J, De Sutter, P, Bosmans, E, Martens, G, ...

A total of 3974 IVF and 1655 ICSI singleton births and 2901 IVF and 1102 ICSI twin births were evaluated. Pregnancies after both fresh and frozen transfers were included. IVF and ICSI singleton...

Xanthine oxidoreductase is present in bile ducts of normal and cirrhotic liver (2004)

Martin, H. M., Moore, K. P., Bosmans, E., Davies, S., Burroughs, A. K., Dhillon, A. P., ...

Xanthine oxidoreductase (XOR) is a widely distributed enzyme, involved in the metabolism of purines, which generates superoxide and is thought to be involved in free radical-generated tissue injury....

Selection and identification of dense granule antigen GRA3 by Toxoplasma gondii whole genome phage display (2002)

Robben, Johan; U0005880, Hertveldt, Kirsten; U0018678, Bosmans, E, Volckaert, Guido; U0006538

Toxoplasma gondii is a ubiquitous, unicellular, eukaryotic parasite with a complex intracellular life cycle capable of invading and chronically infecting a wide variety of vertebrate host species,...

Interleukin (IL)-6, IL-8 and IL-10 in serum and CSF of Trypanosoma brucei gambiense sleeping sickness patients before and after treatment (2002)

Lejon, V., Lardon, J., Kenis, G., Pinoges, L., Legros, D., Bisser, S., ...

Serum and cerebrospinal fluid (CSF) concentrations of interleukin (IL)-6, IL-8, IL-10, tumour necrosis factor-alpha and interferon-gamma were determined in 46 Trypanosoma brucei gambiense sleeping...

Insertion or deletion of the Cheo box modifies radiation inducibility of Clostridium promoters (2001)

Barbé, S, Landuyt, W, ...

Radiation-inducible promoters are being used in many viral vector systems to obtain spatial and temporal control of gene expression. It was previously proven that radiation-induced gene expression...

Improvement of Clostridium tumour targeting vectors evaluated in rat rhabdomyosarcomas (2001)

Landuyt, W, Bosmans, E, Rijnders, A, ...

Previous studies have demonstrated the feasibility of using apathogenic clostridia as a promising strategy for hypoxia-specific tumour targeting. The present study shows that the use of the vascular...

Pathogenesis of abnormal vaginal bacterial flora (2000)

Bosmans, E, Dekeersmaecker, A, Vereecken, A, Van Bulck, B

OBJECTIVE: This study was undertaken to determine the relationships between microscopy findings on wet mounts, such as lactobacillary grade or vaginal leukocytosis, and results of vaginal culture,...

GP130 and c-kit signaling, initiated by the sIL-6R/IL-6 complex, is sufficient to expand the primitive adult bone marrow CD34+CD38-pre-CFU cell (2000)

Van Bockstaele, D. R., Nijs, G., Lenjou, M., Bosmans, E., Vanham, G., Rodrigus, I., ...

It has previously been shown that gp130 and c-kit signalling synergize for the ex vivo expansion of human cord blood (CB) CD34+ haematopoietic progenitor cells. We were interested in evaluating this...

The fetomaternal dependency of cord blood interleukin-6 (1999)

De Jongh, RF, Puylaert, M, Bosmans, E, Ombelet, W, Maes, Marc; U0007401, Heylen, R

Interleukin-6 (IL-6) plays a major role in hematopoiesis, immune functioning, and the acute phase response. In umbilical cord blood, this cytokine was thought to be a marker of neonatal defense to...

Multicenter study on reproducibility of sperm morphology assessments (1998)

Bosmans, E, Janssen, M, Cox, A, Maes, M, Punjabi, U, ...

Sperm morphology has always been considered an important tool in evaluating a man's fertilizing potential. The objective of this multicentric study was to evaluate intra- and interindividual...

Clara cell protein: Concentrations in cerebrospinal fluid, serum and amniotic fluid (1998)

Vranken, J, Kenis, G, Bosmans, E, Stans, G, ...

Clara cell protein (CC16) is an endogenous anti-inflammatory agent. It is produced mainly in the respiratory and urogenital tracts. CC16 has been quantified in serum, but not in cerebrospinal fluid...

The effects of anticoagulation and processing on assays of IL-6, sIL-6R, sIL-2R and soluble transferrin receptor (1997)

DeJongh, R, Vranken, J, Vundelinckx, G, Bosmans, E, Maes, Marc; U0007401, Heylen, R

Levels of plasma cytokines, their receptors or immune-related peptides, are used in experimental and clinical medicine, However, no standards are available regarding the use of anticoagulants or...

Lower plasma CC16, a natural anti-inflammatory protein, and increased plasma interleukin-1 receptor antagonist in schizophrenia: Effects of antipsychotic drugs (1996)

Bosmans, E, Ranjan, R, Vandoolaeghe, E, Meltzer, HY, ...

Recently, it was suggested that in vivo activation of the monocytic and T-lymphocytic arms of cell-mediated immunity (CMI) may occur in schizophrenia and that antipsychotic drugs may modify CMI. The...

Human cytomegalovirus increases constitutive production of interleukin-6 and leukemia inhibitory factor by bone marrow stromal cells (1996)

Delforge, A, Bosmans, E, Moreau, J F, Taupin, J L, ...

Human cytomegalovirus (CMV) infection is often associated with myelosuppression and acute inflammatory reaction in immunocompromised patients. We have previously documented that CMV exposure of bone...

ABSOLUTE NUMBER AND PERCENTAGE OF CIRCULATING NATURAL-KILLER, NON-MHC-RESTRICTED T-CYTOTOXIC, AND PHAGOCYTIC-CELLS IN UNIPOLAR DEPRESSION (1994)

MAES, M, LAMBRECHTS, J, SUY, E, BOSMANS, E, VANDERVORST, Carine

One of the most consistently reported immunological abnormalities in major depression is blunted ex vivo natural killer cell activity (NKCA). This study was designed to investigate the number and...

ABSOLUTE NUMBER AND PERCENTAGE OF CIRCULATING NATURAL-KILLER, NON-MHC-RESTRICTED T-CYTOTOXIC, AND PHAGOCYTIC-CELLS IN UNIPOLAR DEPRESSION (1994)

MAES, M, LAMBRECHTS, J, SUY, E, BOSMANS, E, VANDERVORST, Carine

One of the most consistently reported immunological abnormalities in major depression is blunted ex vivo natural killer cell activity (NKCA). This study was designed to investigate the number and...

Teratozoospermia and in-vitro fertilization: a randomized prospective study (1994)

Ombelet, W., Fourie, F.leR., Vandeput, H., Bosmans, E., Cox, A., Janssen, M., ...

A prospective randomized study was conducted to assess the prognostic value of sperm morphology in an in-vitro fertilization (IVF) programme, using strict criteria. The first group (T,...

An Escherichia coli plasmid vector system for high-level production and purification of heterologous peptides fused to active chloramphenicol acetyltransferase (1993)

Massie, G, Bosmans, E, Wellens, B

A very small plasmid vector system is described for construction and high-level production of C-terminal chloramphenicol acetyltransferase (CAT) fusion proteins in Escherichia coli. The only...

ANTIBODY-BINDING PROFILE OF PURIFIED AND CELL-BOUND CD26 - DESIGNATION OF BT5/9 AND TA5.9 TO THE CD26 CLUSTER (1993)

DEMEESTER, I, SCHARPE, S, VANHAM, G, BOSMANS, E, VANHOOF, G, CORTE, G, ...

The CD26 activation antigen (Ag) which is expressed on a subpopulation of human T cells has been characterized as dipeptidyl peptidase IV (DPP IV, EC 3.4.14.5). In this paper, we describe the...

DECREASED EXPRESSION OF THE MEMORY MARKER CD26 ON BOTH CD4+ AND CD8+ T-LYMPHOCYTES OF HIV-INFECTED SUBJECTS (1993)

VANHAM, G, KESTENS, L, DEMEESTER, I, VINGERHOETS, J, PENNE, G, VANHOOF, G, ...

Using a novel anti-CD26 (or anti-dipeptidyl peptidase IV) monoclonal antibody, we showed that the absolute numbers and the proportions of T4 and T8 cells expressing CD26 were significantly lower in...

ANTIBODY-BINDING PROFILE OF PURIFIED AND CELL-BOUND CD26 - DESIGNATION OF BT5/9 AND TA5.9 TO THE CD26 CLUSTER (1993)

DEMEESTER, I, SCHARPE, S, VANHAM, G, BOSMANS, E, VANHOOF, G, CORTE, G, ...

The CD26 activation antigen (Ag) which is expressed on a subpopulation of human T cells has been characterized as dipeptidyl peptidase IV (DPP IV, EC 3.4.14.5). In this paper, we describe the...

DECREASED EXPRESSION OF THE MEMORY MARKER CD26 ON BOTH CD4+ AND CD8+ T-LYMPHOCYTES OF HIV-INFECTED SUBJECTS (1993)

VANHAM, G, KESTENS, L, DEMEESTER, I, VINGERHOETS, J, PENNE, G, VANHOOF, G, ...

Using a novel anti-CD26 (or anti-dipeptidyl peptidase IV) monoclonal antibody, we showed that the absolute numbers and the proportions of T4 and T8 cells expressing CD26 were significantly lower in...

DISTURBANCES IN ACUTE PHASE PLASMA-PROTEINS DURING MELANCHOLIA - ADDITIONAL EVIDENCE FOR THE PRESENCE OF AN INFLAMMATORY PROCESS DURING THAT ILLNESS (1992)

MAES, M, SCHARPE, S, BOSMANS, E, VANDEWOUDE, M, SUY, E, UYTTENBROECK, W, ...

1. Leukocyte enumeration through flow cytometry has revealed that severe depression may be accompanied by a systemic immune activation, indicative of an inflammatory response. The latter condition...

EVIDENCE FOR A SYSTEMIC IMMUNE ACTIVATION DURING DEPRESSION - RESULTS OF LEUKOCYTE ENUMERATION BY FLOW-CYTOMETRY IN CONJUNCTION WITH MONOCLONAL-ANTIBODY STAINING (1992)

MAES, M, LAMBRECHTS, J, BOSMANS, E, JACOBS, J, SUY, E, DEJONCKHEERE, C, ...

Several studies have reported a suppressed immune function (e.g. blast transformation) during depression. In an attempt to define the cellular basis of the reported immune disorders, the present...

DISTURBANCES IN ACUTE PHASE PLASMA-PROTEINS DURING MELANCHOLIA - ADDITIONAL EVIDENCE FOR THE PRESENCE OF AN INFLAMMATORY PROCESS DURING THAT ILLNESS (1992)

MAES, M, SCHARPE, S, BOSMANS, E, VANDEWOUDE, M, SUY, E, UYTTENBROECK, W, ...

1. Leukocyte enumeration through flow cytometry has revealed that severe depression may be accompanied by a systemic immune activation, indicative of an inflammatory response. The latter condition...

EVIDENCE FOR A SYSTEMIC IMMUNE ACTIVATION DURING DEPRESSION - RESULTS OF LEUKOCYTE ENUMERATION BY FLOW-CYTOMETRY IN CONJUNCTION WITH MONOCLONAL-ANTIBODY STAINING (1992)

MAES, M, LAMBRECHTS, J, BOSMANS, E, JACOBS, J, SUY, E, DEJONCKHEERE, C, ...

Several studies have reported a suppressed immune function (e.g. blast transformation) during depression. In an attempt to define the cellular basis of the reported immune disorders, the present...

Alpha-1-proteinase inhibitor gene frequencies in Belgium (1991)

Kimpen, J, Legius, Eric; U0003408, Bosmans, E, Van Vaerenbergh, V, Ramon, A, Raus, J

The alpha-1-antitrypsin phenotype was determined in cord blood of 1345 Belgian newborns by isoelectric focusing in polyacrylamide gels. Proteinase inhibitor (PI) gene frequencies were calculated. The...

IMMUNE DISTURBANCES DURING MAJOR DEPRESSION - UP-REGULATED EXPRESSION OF INTERLEUKIN-2 RECEPTORS (1991)

MAES, M, BOSMANS, E, SUY, E, DEJONCKHEERE, C, VANDERVORST, Carine, RAUS, Jef

We determined the following immune parameters in drug-free, major depressed patients and in age- and sex-matched healthy controls: the number and percentage of interleukin-2 receptor (IL-2R) bearing...

DEPRESSION-RELATED DISTURBANCES IN MITOGEN-INDUCED LYMPHOCYTE-RESPONSES AND INTERLEUKIN-1-BETA AND SOLUBLE INTERLEUKIN-2 RECEPTOR PRODUCTION (1991)

MAES, M, BOSMANS, E, SUY, E, DEJONCKHEERE, C, VANDERVORST, Carine, RAUS, Jef

In an attempt to delineate the pathophysiology underpinning the previously reported blunted lymphocyte responses to mitogenic stimulation in depressed patients, we measured the following immune...

DECREASED SERUM DIPEPTIDYL PEPTIDASE-IV ACTIVITY IN MAJOR DEPRESSION (1991)

MAES, M, DEMEESTER, I, VANHOOF, G, SCHARPE, S, BOSMANS, E, VERKERK, R, ...

It has been recently shown that severe depression is characterized by immune dysfunctions such as blunted mitogen-induced blast transformation, which is linked to interleukin-2 (IL-2) mechanisms, and...

A FURTHER EXPLORATION OF THE RELATIONSHIPS BETWEEN IMMUNE PARAMETERS AND THE HPA-AXIS ACTIVITY IN DEPRESSED-PATIENTS (1991)

MAES, M, BOSMANS, E, SUY, E, MINNER, B, RAUS, Jef

In order to investigate the relationship between the immune apparatus and the hypothalamic-pituitary-adrenal (HPA)-axis activity in depressed patients, we measured in vitro lymphocyte responses to...

ANTIPHOSPHOLIPID, ANTINUCLEAR, EPSTEIN-BARR AND CYTOMEGALOVIRUS ANTIBODIES, AND SOLUBLE INTERLEUKIN-2 RECEPTORS IN DEPRESSIVE PATIENTS (1991)

MAES, M, BOSMANS, E, SUY, E, DEJONCKHEERE, C, VANDERVORST, Carine, RAUS, Jef

To determine whether depression might be associated with serologic indices of autoimmune processes or active virus infections, we measured the following parameters in healthy controls, minor, simple...

IMMUNE DISTURBANCES DURING MAJOR DEPRESSION - UP-REGULATED EXPRESSION OF INTERLEUKIN-2 RECEPTORS (1991)

MAES, M, BOSMANS, E, SUY, E, DEJONCKHEERE, C, VANDERVORST, Carine, RAUS, Jef

We determined the following immune parameters in drug-free, major depressed patients and in age- and sex-matched healthy controls: the number and percentage of interleukin-2 receptor (IL-2R) bearing...

DEPRESSION-RELATED DISTURBANCES IN MITOGEN-INDUCED LYMPHOCYTE-RESPONSES AND INTERLEUKIN-1-BETA AND SOLUBLE INTERLEUKIN-2 RECEPTOR PRODUCTION (1991)

MAES, M, BOSMANS, E, SUY, E, DEJONCKHEERE, C, VANDERVORST, Carine, RAUS, Jef

In an attempt to delineate the pathophysiology underpinning the previously reported blunted lymphocyte responses to mitogenic stimulation in depressed patients, we measured the following immune...

DECREASED SERUM DIPEPTIDYL PEPTIDASE-IV ACTIVITY IN MAJOR DEPRESSION (1991)

MAES, M, DEMEESTER, I, SCHARPE, S, BOSMANS, E, VANDERVORST, Carine, RAUS, Jef, ...

It has been recently shown that severe depression is characterized by immune dysfunctions such as blunted mitogen-induced blast transformation, which is linked to interleukin-2 (IL-2) mechanisms, and...

A FURTHER EXPLORATION OF THE RELATIONSHIPS BETWEEN IMMUNE PARAMETERS AND THE HPA-AXIS ACTIVITY IN DEPRESSED-PATIENTS (1991)

MAES, M, BOSMANS, E, SUY, E, MINNER, B, RAUS, Jef

In order to investigate the relationship between the immune apparatus and the hypothalamic-pituitary-adrenal (HPA)-axis activity in depressed patients, we measured in vitro lymphocyte responses to...

ANTIPHOSPHOLIPID, ANTINUCLEAR, EPSTEIN-BARR AND CYTOMEGALOVIRUS ANTIBODIES, AND SOLUBLE INTERLEUKIN-2 RECEPTORS IN DEPRESSIVE PATIENTS (1991)

MAES, M, BOSMANS, E, SUY, E, VANDERVORST, Carine, DEJONCKHEERE, C, RAUS, Jef

To determine whether depression might be associated with serologic indices of autoimmune processes or active virus infections, we measured the following parameters in healthy controls, minor, simple...

Decreased dispeptidyl-peptidase IV activity in serum of major depressed patients (1991)

Maes, M., De Meester, I., Vanhoof, G, Scharpé, S., Bosmans, E., Vandervorst, C., ...

It has been recently shown that severe depression is characterized by immune dysfunctions such as blunted mitogen-induced blast transformation, which is linked to interleukin-2 (IL-2) mechanisms, and...

Insertion or Deletion of the Cheo Box Modifies Radiation Inducibility of Clostridium Promoters

Nuyts, S., Van Mellaert, L., Barbé, S., Lammertyn, E., Theys, J., Landuyt, W., ...

Radiation-inducible promoters are being used in many viral vector systems to obtain spatial and temporal control of gene expression. It was previously proven that radiation-induced gene expression...

Insertion or Deletion of the Cheo Box Modifies Radiation Inducibility of Clostridium Promoters

Nuyts, S., Van Mellaert, L., Barbé, S., Lammertyn, E., Theys, J., Landuyt, W., ...

Radiation-inducible promoters are being used in many viral vector systems to obtain spatial and temporal control of gene expression. It was previously proven that radiation-induced gene expression...

CD8+ T cells and not CD4+ T cells are hyporesponsive to CD28- and CD40L-mediated activation in HIV-infected subjects

VINGERHOETS, J, KESTENS, L, PENNE, G, DE VUYST, H, VANDENBRUAENE, M, PELGROM, Y, ...

T cell dysfunction in HIV-infected subjects could be the consequence of altered sensitivity of CD4+ or CD8+ T cells to various costimulatory signals. Therefore, we studied proliferation and cytokine...

Superantigen activation of CD4+ and CD8+ T cells from HIV-infected subjects: role of costimulatory molecules and antigen-presenting cells (APC)

Vingerhoets, J, Dohlsten, M, Penne, G, Colebunders, R, Sansom, D, Bosmans, E, ...

T cell receptor (TCR) triggering via superantigens induces decreased proliferative responses and increased apoptosis in T cells from HIV-infected patients compared with controls. Our aim was to...

Decreased CD40 ligand induction in CD4 T cells and dysregulated IL-12 production during HIV infection

Vanham, G, Penne, L, Devalck, J, Kestens, L, Colebunders, R, Bosmans, E, ...

During HIV infection various cytokines are overproduced in early stages, whereas in advanced disease cytokines of the T helper 1 type (e.g. interferon-gamma (IFN-γ)) are selectively deficient....

Cord blood IgE and month of birth.

Kimpen, J, Callaert, H, Embrechts, P, Bosmans, E

If cord blood IgE is used to detect those predisposed to become allergic it is important to define appropriately the normal values for this measurement. A commonly cited cut off point is 1.0 IU/ml....

Constitutive expression of CD26/dipeptidylpeptidase IV on peripheral blood B lymphocytes of patients with B chronic lymphocytic leukaemia

Bauvois, B, Meester, I De, Dumont, J, Rouillard, D, Zhao, H X, Bosmans, E

We have investigated the expression of the ectoenzyme dipeptidylpeptidase IV (DPP IV)/CD26 on lymphocytes obtained from patients with B chronic lymphocytic leukaemia (B-CLL) and compared it with...