Nordmann, Jean J., Dayanithi, Govindan, Stuenkel, Edward L.
Rat neural lobes and isolated nerve terminals from the neurohypophysis were stimulated in the presence of different opioid agonists and antagonists. The secretion of arginine vasopressin and oxytocin...
Ca2+-independent regulation of neurosecretion by intracellular Na+ (1991)
Nordmann, Jean J., Stuenkel, Edward L.
While secretion from nerve endings is strictly controlled by an increase in cytoplasmic free calcium several reports suggest intracellular sodium may serve a regulatory role. Whether sodium acts...
Stuenkel, Edward L., Cooke, I., Gillary, E.
Sections of isolated X-organ — sinus gland neurosecretory systems of the crab, Cardisoma carnifex , were studied by light-and electron microscopy with conventional and autoradiographic procedures....
Effects of membrane depolarization on intracellular calcium in single nerve terminals (1990)
The [Ca2+]i of individual neurosecretory nerve terminals loaded with the fluorescent probe fura-2 was monitored during depolarizing stimuli and in the presence of substances known to induce or block...
Secretagogue effects on intracellular calcium in pancreatic duct cells (1990)
Hootman, Seth R., Stuenkel, Edward L.
Regulation of intracellular free calcium ([Ca 2+ ] i ) in single epithelial duct cells of isolated rat and guinea pig pancreatic interlobular ducts by secretin, carbachol and cholecystokinin was...
Secretagogue induced calcium mobilization in single pancreatic acinar cells (1989)
Stuenkel, Edward L., Tsunoda, Yasuhiro, Williams, John A.
Microspectrofluorometry of fura-2 was utilized to monitor [Ca2+]i in single acinar cells stimulated with a cholinergic agonist and cholecystokinin. A similar amplitude of agonist induced Ca...
Ghrelin stimulates neurogenesis in the dorsal motor nucleus of the vagus
Zhang, Weizhen, Lin, Theodore R, Hu, Yuexuan, Fan, Yongyi, Zhao, Lili, Stuenkel, Edward L, ...
Ghrelin, a gastric peptide hormone, has been reported to regulate growth hormone secretion and energy homeostasis. Here we show that ghrelin promotes neural proliferation in vivo and in vitro in the...
Soldo, Brandi L, Giovannucci, David R, Stuenkel, Edward L, Moises, Hylan C
In addition to action potential-evoked exocytotic release at neurohypophysial nerve terminals, the neurohormones arginine vasopressin (aVP) and oxytocin (OT) undergo Ca2+-dependent somatodendritic...
Regulation of syntaxin1A–munc18 complex for SNARE pairing in HEK293 cells
Gladycheva, Svetlana E, Ho, Chi S, Lee, Yue Ying F, Stuenkel, Edward L
The formation and dissolution of SNARE protein complexes is essential for Ca2+-triggered fusion of neurotransmitter-filled vesicles at the presynaptic membrane. Among the pre-synaptic SNARE proteins,...
Soldo, Brandi L, Giovannucci, David R, Stuenkel, Edward L, Moises, Hylan C
In addition to action potential-evoked exocytotic release at neurohypophysial nerve terminals, the neurohormones arginine vasopressin (aVP) and oxytocin (OT) undergo Ca2+-dependent somatodendritic...
Regulation of syntaxin1A–munc18 complex for SNARE pairing in HEK293 cells
Gladycheva, Svetlana E, Ho, Chi S, Lee, Yue Ying F, Stuenkel, Edward L
The formation and dissolution of SNARE protein complexes is essential for Ca2+-triggered fusion of neurotransmitter-filled vesicles at the presynaptic membrane. Among the pre-synaptic SNARE proteins,...
Ghrelin stimulates neurogenesis in the dorsal motor nucleus of the vagus
Zhang, Weizhen, Lin, Theodore R, Hu, Yuexuan, Fan, Yongyi, Zhao, Lili, Stuenkel, Edward L, ...
Ghrelin, a gastric peptide hormone, has been reported to regulate growth hormone secretion and energy homeostasis. Here we show that ghrelin promotes neural proliferation in vivo and in vitro in the...
SNARE-catalyzed Fusion Events Are Regulated by Syntaxin1A–Lipid Interactions
Lam, Alice D., Tryoen-Toth, Petra, Tsai, Bill, Vitale, Nicolas, Stuenkel, Edward L.
Membrane fusion is a process that intimately involves both proteins and lipids. Although the SNARE proteins, which ultimately overcome the energy barrier for fusion, have been extensively studied,...
Facilitation of Ca2+-dependent exocytosis by Rac1-GTPase in bovine chromaffin cells
Li, Quanwen, Ho, Chi S, Marinescu, Vlad, Bhatti, Humaa, Bokoch, Gary M, Ernst, Stephen A, ...
Rho family GTPases are primary mediators of cytoskeletal reorganization, although they have also been reported to regulate cell secretion. Yet, the extent to which Rho family GTPases are activated by...
Kinetics of Rab27a-dependent actions on vesicle docking and priming in pancreatic β-cells
Merrins, Matthew J, Stuenkel, Edward L
The small GTPase Rab27a, along with the isoforms of Rab3, is present on insulin secretory granules and has been implicated in regulation of Ca2+-triggered exocytosis. We have used membrane...