† These authors contributed equally to this work. RESEARCH ARTICLE Contact: (2008)
Kristoffer Forslund, Anna Henricson, Volker Hollich, Erik Sonnhammer
protein domain architecture evolution MBE Advance Access published November 19, 2007 Running head: Analysis of protein architecture evolution
The complete genome sequence of the nematode Caenorhabditis elegans provides an excellent basis for studying the distribution and evolution of protein families in higher eukaryotes. Three fundamental...
Design of a new siRNA prediction method using SVMs. (2006)
Supervisor Prof, Erik Sonnhammer
Sequence analysis of transcription factor binding sites in bone formation.
Quality Assessment of Multiple Alignment Programs (2002)
Timo Lassmann, Erik Sonnhammer, Poa Dialign
ArenewP interest in the multiple sequence alignment problem has given rise to severalnew algorithms. In contrast to traditional progressive methods, computationally expensive score optimization...
The Pfam Protein Families Database (2000)
Alex Bateman, Ewan Birney, Richard Durbin, Sean R. Eddy, Kevin L. Howe, Erik Sonnhammer, ...
Pfam is a large collection of protein multiple sequence alignments and profile hidden Markov models. Pfam is available on the World Wide Web in the UK at http://www.sanger.ac.uk/Software/Pfam/, in...
A hidden Markov model for predicting transmembrane helices in protein sequences (1998)
Erik Sonnhammer, Gunnar Von Heijne, Anders Krogh
A novel method to model and predict the location and orientation of alpha helices in membrane- spanning proteins is presented. It is based on a hidden Markov model (HMM) with an architecture that...
The complete genome sequence of the nematode Caenorhabditis elegans provides an excellent basis for studying the distribution and evolution of protein families in higher eukaryotes. Three fundamental...
The complete genome sequence of the nematode Caenorhabditis elegans provides an excellent basis for studying the distribution and evolution of protein families in higher eukaryotes. Three fundamental...