Reynolds, R.M., Ilyas, B., Price, J.F., Fowkes, F.G.R., Newby, D.E., Webb, D.J., ...
Background: Although the prevalence of cardiovascular disease is declining, the obesity epidemic with associated metabolic syndrome may reverse this trend. Hypothalamic–pituitary–adrenal (HPA)...
Danesh, J, Erqou, S, Walker, M, Thompson, S G, Tipping, R, Ford, C, ...
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Kostis, J.B., Wilson, A.C., Folsom, A.R., Chambless, L., Wu, K., Benderly, M., ...
Background Many long-term studies have reported on associations of plasma fibrinogen concentration with cardiovascular disease, but few have been large enough to provide reliable estimates in...
The prevalence of prophylaxis for deep vein thrombosis in acute hospital trusts (2004)
Campbell, S.E., Walker, A.E., Grimshaw, J.M., Campbell, M.K., Lowe, G.D.O., Harper, D., ...
Objective. The effectiveness of activities to promote routine prophylaxis to prevent thromboembolism is difficult to assess because information about the prevalence of prophylaxis is sparse. The aim...
Price, J.F., Lee, A.J., Rumley, A., Lowe, G.D.O., Fowkes, F.G.R.
Lipoprotein (a) may be an important risk factor for atherosclerosis. It is widely accepted that lipoprotein (a) levels are raised in patients with coronary heart disease, but there is some doubt...
Lee, A.J., Lowe, G.D.O., Rumley, A., Ruckley, C.V., Fowkes, F.G.R.
Despite much research, the aetiology of venous disease is still poorly understood. Since haemostatic factors are involved in the processes of fibrinolysis and platelet aggregation, it is conceivable...
Smith, F.B., Lee, A.J., Hau, C.M., Rumley, A., Lowe, G.D.O., Fowkes, F.G.R.
The role of fibrinogen and other haemostatic factors in prediction of peripheral arterial disease (PAD) has not been established. We examined the associations of plasma fibrinogen, von Willebrand...
Fowkes, F.G.R., Lee, A.J., Hau, C.M., Cooke, A., Connor, J.M., Lowe, G.D.O.
Hyperhomocysteinaemia and reduced nitric oxide synthesis may each result in endothelial dysfunction predisposing to atherogenesis. Genetic variants of methylene tetrahydrofolate reductase (MTHFR) and...
Smith, F.B., Fowkes, F.G.R., Rumley, A., Lee, A.J., Lowe, G.D.O., Hau, C.M.
Aims To evaluate the relationship between haemostatic and rheological factors and cardiovascular outcome in subjects with angina pectoris in the general population. Methods and Results Two hundred...
Smith, F.B, Fowkes, F.G.R, Rumley, A, Lee, A.J, Lowe, G.D.O, Hau, C.M
Aims To evaluate the relationship between haemostatic and rheological factors and cardiovascular outcome in subjects with angina pectoris in the general population. Methods and Results Two hundred...
Price, J.F., Mowbray, P.I., Lee, A.J., Rumley, A., Lowe, G.D.O., Fowkes, F.G.R.
Aims The aim was to determine whether the effect of smoking on the development of peripheral or coronary artery disease might be mediated by other cardiovascular risk factors, including dietary...
Smoking, atherosclerosis and risk of abdominal aortic aneurysm (1997)
Lee, A. J., Fowkes, F. G. R., Carson, M. N., Leng, G. C., Allan, P. L.
Aims The role of cardiovascular risk factors and atherosclerosis in the aetiology of abdominal aortic aneurysms is not well understood. The aim of this study was to determine the association between...
LENG, G. C., LEE, A. J., FOWKES, F. G. R., LOWE, G. D. O., HOUSLEY, E.
Cigarette smoking is probably the most important risk factor for the development of peripheral arterial disease, but it may be less important in the aetiology of ischaemic heart disease. The...
Fibrinogen and Peripheral Arterial Disease (1995)
Both hospital and epidemiological studies have reported elevated plasma fibrinogen levels in patients with intermittent claudication. Fibrinogen levels have also been positively related to the degree...
Fibrinogen and Cardiovascular Disease in Clinical Practice (1995)
Plasma fibrinogen is not measured routinely in clinical practice for prediction of cardiovascular disease (CVD) but further modest advances in the research investigating fibrinogen and CVD may make...
FOWKES, F. G. R., LOWE, G. D. O., RUMLEY, A., LENNIE, S. E., SMITH, F. B., DONNAN, P. T.
Blood viscosity is elevated in hypertensive subjects, but the association of viscosity with arterial blood pressure in the general population, and the influence of social, lifestyle and disease...
FOWKES, F G R, HOUSLEY, E, CAWOOD, E H H, MACINTYRE, C C A, RUCKLEY, C V, PRESCOTT, R J
Intermittent claudication has been studied in cardiovascular surveys but limited information is available on asymptomatic peripheral arterial disease. The purpose of this paper is to describe the...
The Measurement of Atherosclerotic Peripheral Arterial Disease in Epidemiological Surveys (1988)
In cardiovascular surveys, the WHO questionnaire on intermittent claudication has traditionally been used as a measure of atherosclerotic peripheral arterial disease of the lower limbs. But the...
Epidemiology for Medical Students: A Controlled Trial of Three Teaching Methods (1985)
GEHLBACH, S H, FARROW, S C, FOWKES, F G R, WEST, R R, ROBERTS, C J
Gehlbach S H (Department of Epidemiology and Community Medicine, Welsh National School of Medicine, Heath Park, Cardiff CF4 4XN, UK), Farrow S C, Fowkes F G R, West R R and Roberts C J. Epidemiology...
The role of clinical epidemiology in medical practice (1984)
Fowkes, F. G. R., Dobson, A. J., Hensley, M. J., Leeder, S. R.
Epidemiology for Medical Students: A Course Relevant to Clinical Practice (1984)
FOWKES, F G R, GEHLBACH, S H, FARROW, S C, WEST, R R, ROBERTS, C J
Fowkes F G R (Department of Epidemiology and Community Medicine, Welsh National School of Medicine, Heath Park, Cardiff, CF4 4XN, UK), Gehlbach S H, Farrow S C, West R R and Roberts C J. Epidemiology...
EPIDEMIOLOGY IN ANAESTHESIA: I: ANAESTHETIC PRACTICE OVER 20 YEARS (1982)
LUNN, J. N., FARROW, S C., FOWKES, F G. R, ROBERTSON, I B., SAMUEL, P.
The practice of anaesthesia and its outcome is compared, by means of the Cardiff Anaesthetic Record System, between two periods of 6 years, in whiph 53 541 and 108 878 anaesthetics were administered...
EPIDEMIOLOGY IN ANAESTHESIA II: FACTORS AFFECTING MORTALITY IN HOSPITAL (1982)
FARROW, S C, FOWKES, F G R., LUNN, J. N., ROBERTSON, I B, SAMUEL, P.
The hospital mortality following 108 878 anaesthetics in Cardiff between 1972 and 1977 has been analysed. There was a total of 2391 deaths, giving a crude mortality rate of 2 2 per 100 patients. Data...
EPIDEMIOLOGY IN ANAESTHESIA III: MORTALITY RISK IN PATIENTS WITH COEXISTING PHYSICAL DISEASE (1982)
FOWKES, F.G.R., LUNN, J N, FARROW, S.C, ROBERTSON, I.B, SAMUEL, P.
The Cardiff Anaesthetic Record System has been used to examine the hospital mortality rates and relative risks for patients having anaesthesia who have certain preoperative conditions coexisting with...
Collaborative meta-analysis of prospective studies of plasma fibrinogen and cardiovascular disease
Kostis, J.B., Wilson, A.C., Folsom, A.R., Chambless, L., Wu, K., Benderly, M., ...
Background Many long-term studies have reported on associations of plasma fibrinogen concentration with cardiovascular disease, but few have been large enough to provide reliable estimates in...
The prevalence of prophylaxis for deep vein thrombosis in acute hospital trusts
Campbell, S.E., Walker, A.E., Grimshaw, J.M., Campbell, M.K., Lowe, G.D.O., Harper, D., ...
Objective. The effectiveness of activities to promote routine prophylaxis to prevent thromboembolism is difficult to assess because information about the prevalence of prophylaxis is sparse. The aim...
Lee, A.J., Lowe, G.D.O., Rumley, A., Ruckley, C.V., Fowkes, F.G.R.
Despite much research, the aetiology of venous disease is still poorly understood. Since haemostatic factors are involved in the processes of fibrinolysis and platelet aggregation, it is conceivable...
Price, J.F., Lee, A.J., Rumley, A., Lowe, G.D.O., Fowkes, F.G.R.
Lipoprotein (a) may be an important risk factor for atherosclerosis. It is widely accepted that lipoprotein (a) levels are raised in patients with coronary heart disease, but there is some doubt...
Smith, F.B., Lee, A.J., Hau, C.M., Rumley, A., Lowe, G.D.O., Fowkes, F.G.R.
The role of fibrinogen and other haemostatic factors in prediction of peripheral arterial disease (PAD) has not been established. We examined the associations of plasma fibrinogen, von Willebrand...
Fowkes, F.G.R., Lee, A.J., Hau, C.M., Cooke, A., Connor, J.M., Lowe, G.D.O.
Hyperhomocysteinaemia and reduced nitric oxide synthesis may each result in endothelial dysfunction predisposing to atherogenesis. Genetic variants of methylene tetrahydrofolate reductase (MTHFR) and...
Smith, F.B., Fowkes, F.G.R., Rumley, A., Lee, A.J., Lowe, G.D.O., Hau, C.M.
Aims To evaluate the relationship between haemostatic and rheological factors and cardiovascular outcome in subjects with angina pectoris in the general population. Methods and Results Two hundred...
What are the symptoms of varicose veins? Edinburgh vein study cross sectional population survey
Bradbury, Andrew, Evans, Christine, Allan, Paul, Lee, Amanda, Ruckley, C Vaughan, Fowkes, F G R
What are the symptoms of varicose veins? Edinburgh vein study cross sectional population survey
Bradbury, Andrew, Evans, Christine, Allan, Paul, Lee, Amanda, Ruckley, C Vaughan, Fowkes, F G R
Collaborative meta-analysis of prospective studies of plasma fibrinogen and cardiovascular disease
Kostis, J.B., Wilson, A.C., Folsom, A.R., Chambless, L., Wu, K., Benderly, M., ...
Background Many long-term studies have reported on associations of plasma fibrinogen concentration with cardiovascular disease, but few have been large enough to provide reliable estimates in...
The prevalence of prophylaxis for deep vein thrombosis in acute hospital trusts
Campbell, S.E., Walker, A.E., Grimshaw, J.M., Campbell, M.K., Lowe, G.D.O., Harper, D., ...
Objective. The effectiveness of activities to promote routine prophylaxis to prevent thromboembolism is difficult to assess because information about the prevalence of prophylaxis is sparse. The aim...
Lee, A.J., Lowe, G.D.O., Rumley, A., Ruckley, C.V., Fowkes, F.G.R.
Despite much research, the aetiology of venous disease is still poorly understood. Since haemostatic factors are involved in the processes of fibrinolysis and platelet aggregation, it is conceivable...
Price, J.F., Lee, A.J., Rumley, A., Lowe, G.D.O., Fowkes, F.G.R.
Lipoprotein (a) may be an important risk factor for atherosclerosis. It is widely accepted that lipoprotein (a) levels are raised in patients with coronary heart disease, but there is some doubt...
Smith, F.B., Lee, A.J., Hau, C.M., Rumley, A., Lowe, G.D.O., Fowkes, F.G.R.
The role of fibrinogen and other haemostatic factors in prediction of peripheral arterial disease (PAD) has not been established. We examined the associations of plasma fibrinogen, von Willebrand...
Fowkes, F.G.R., Lee, A.J., Hau, C.M., Cooke, A., Connor, J.M., Lowe, G.D.O.
Hyperhomocysteinaemia and reduced nitric oxide synthesis may each result in endothelial dysfunction predisposing to atherogenesis. Genetic variants of methylene tetrahydrofolate reductase (MTHFR) and...
Smith, F.B., Fowkes, F.G.R., Rumley, A., Lee, A.J., Lowe, G.D.O., Hau, C.M.
Aims To evaluate the relationship between haemostatic and rheological factors and cardiovascular outcome in subjects with angina pectoris in the general population. Methods and Results Two hundred...