Scientific Commons: F. Lottspeich

Abstract: Recent developments in proteomics technology offer new opportunities for clinical applications in hospital or specialized laboratories including the identification of novel biomarkers,...

KDEL-tailed cysteine endopeptidases involved in programmed cell death, intercalation of new cells, and dismantling of extensin scaffolds (2008)

Helm, M., Schmid, M., Hierl, G., Terneus, K., Tan, L., Lottspeich, F., ...

Matching of oligoclonal immunoglobulin transcriptomes and proteomes of cerebrospinal fluid in multiple sclerosis (2008)

Obermeier, B., Mentele, R., Malotka, J., Kellermann, J., Kümpfel, T., Wekerle, H., ...

Oms38 Is the First Identified Pore-Forming Protein in the Outer Membrane of Relapsing Fever Spirochetes (2008)

Thein, M., Bunikis, I., Denker, K., Larsson, C., Cutler, S., Drancourt, M., ...

EuPA achieves visibility - An activity report on the first three years (2008)

Dunn, M. J., Gil, C., Kleinhammer, C., Lottspeich, F., Pennington, S., Sanchez, J. C., ...

KDEL-tailed cysteine endopeptidases involved in programmed cell death, intercalation of new cells, and dismanteling of extensin scaffolds. (2008)

Helm, M., Schmid, M., Hierl, G., Terneus, K., Tan, L., Lottspeich, F., ...

Involvement of a Golgi-resident GPI-anchored protein in maintenance of the Golgi structure (2007)

Li, X. Y., Kaloyanova, D., Van Eijk, M., Eerland, R., Orschot, V., ...

Ferritin - A mediator of apoptosis? (2007)

Bresgen, N., Ohlenschlager, I., Fiedler, B., Wachv, N., Zach, S., Dunkelmann, B., ...

Protein kinase CK2 activates the atypical Rio1p kinase and promotes its cell-cycle phase-dependent degradation in yeast (2007)

Angermayr, M., Hochleitner, E., Lottspeich, F., Bandlow, W.

Dual specificities of the glyoxysomal/peroxisomal processing protease Deg15 in higher plants (2007)

Helm, M., Luck, C., Prestele, J., Hierl, G., Huesgen, P. F., Froehlich, T., ...

Protein synthesis patterns reveal a complex regulatory response to singlet oxygen in Rhodobacter (2007)

Glaeser, J., Zobawa, M., Lottspeich, F., Klug, G.

The human fatty acid synthase: A new therapeutic target for coxsackievirus B3-induced diseases? (2007)

Rassmann, A., Henke, A., Jarasch, N., Lottspeich, F., Saluz, H. P., Munder, T.

Plasma Proteomics of Colon Cancer Patients—The Individual Regulation of Protein Isoforms Identified by the ICPL Technology (2007)

Keidel, E., Brunner, A., Halder, T., Suckau, D., Martin, S., Kellermann, J., ...

Non-Isobaric Triplex-Labeling Strategies for Proteomics (2007)

Schweiger-Hufnagel, U., Behrens, M., Hahner, S., Keidel, E., Dosch, D., Martin, S., ...

Involvement of a Golgi-resident GPI-anchored protein in maintenance of the Golgi structure (2007)

Li, X., Kaloyanova, D., Van Eijk, M., Eerland, R., Oorschot, V., ...

The Golgi apparatus consists of a series of flattened cisternal membranes that are aligned in parallel to form stacks. Cytosolic-oriented Golgi-associated proteins have been identified that may...

Temperature-sensitive eIF5A mutant accumulates transcripts targeted to the nonsense-mediated decay pathway (2006)

Schrader, R., Young, C., Kozian, D., Hoffmann, R., Lottspeich, F.

Tyrosine phosphorylated Par3 regulates epithelial tight junction assembly promoted by EGFR signaling (2006)

Wang, Y. G., Du, D., Fang, L. H., Yang, G., Zhang, C. Y., Zeng, R., ...

Hypophosphorylation of the architectural chromatin protein DEK in death-receptor-induced apoptosis revealed by the isotope coded protein label proteomic platform (2006)

Tabbert, A., Kappes, F., Knippers, R., Kellermann, J., Lottspeich, F., Ferrando-May, E.

Proteinreinigung (2006)

Lottspeich, F.

Bioanalytik - eine eigenständige Wissenschaft (2006)

Lottspeich, F.

Proteomanalyse (2006)

Lottspeich, F.

Proteinsequenzanalyse (2006)

Lottspeich, F.

Proteome alterations in human host cells infected with coxsackievirus B3 (2006)

Rassmann, A., Henke, A., Zobawa, M., Carlsohn, M., Saluz, H. P., Grabley, S., ...

Quantitative analysis of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced proteome alterations in 5L rat hepatoma cells using isotope-coded protein labels (2006)

Sarioglu, H., Brandner, S., Jacobsen, C., Meindl, T., Schmidt, A., Kellermann, J., ...

Proteomic identification of new metal-protein interactions in human antigen-presenting cells reveals a potential link to metal-specific immune responses in human nickel allergy (2006)

Junkes, C., Guerreiro, N., Wild, D., Eikelmeier, S., Weltzien, H., Lottspeich, F., ...

Quantitative profiling of the membrane proteome in a halophilic archaeon (2006)

Bisle, B., Schmidt, A., Scheibe, B., Klein, C., Tebbe, A., Kellermann, J., ...

Evaluation of a novel rapid one-step monoclonal enzyme immunoassay for detection of Helicobacter pylori antigen in stool in children paediatric issues (2006)

Schwarzer, A., Lottspeich, F., Russmann, H., Ossiander, G., Koletzko, S.

Protein isoforms in cancer, identified and quantified by the ICPL (isotope-coded protein labelling) technology (2006)

Halder, T. M., Keidel, E., Dosch, D., Kersten, M., Kellermann, J., Lottspeich, F.

Aminopeptidase N (CD13) is a molecular target of the cholesterol absorption inhibitor ezetimibe in the enterocyte brush border membrane (2005)

Kramer, W., Girbig, F., Corsiero, D., Pfenninger, A., Frick, W., Jahne, G., ...

Protein stoichiometry of a multiprotein complex, the human spliceosomal U1 small nuclear ribonucleoprotein - Absolute quantification using isotope-coded tags and mass spectrometry (2005)

Hochleitner, E. O., Kastner, B., Froehlich, T., Schmidt, A., Luehrmann, R., Arnold, G., ...

Protein stoichiometry of a multiprotein complex, the human spliceosomal U1 small nuclear ribonucleoprotein - Absolute quantification using isotope-coded tags and mass spectrometry (2005)

Hochleitner, E. O., Kastner, B., Frohlich, T., Schmidt, A., Lührmann, R., Arnold, G., ...

cAMP-dependent tyrosine phosphorylation of subunit I inhibits cytochrome c oxidase activity (2005)

Lee, I., Salomon, A. R., Ficarro, S., Mathes, I., Lottspeich, F., Grossman, L. I., ...

Afamin is a novel human vitamin E-binding glycoprotein characterization and in vitro expression (2005)

Jerkovic, L., Voegele, A. F., Chwatal, S., Kronenberg, F., Radcliffe, C. M., Wormald, M. R., ...

B7/CD28 costimulation of T cells induces a distinct proteome pattern (2005)

Kronfeld, K., Hochleitner, E., Mendler, S., Goldschmidt, J., Lichtenfels, R., Lottspeich, F., ...

Afamin is a novel human vitamin E-binding glycoprotein characterization and in vitro expression (2005)

Jerkovic, L., Voegele, A. F., Chwatal, S., Kronenberg, F., Radcliffe, C. M., Wormald, M. R., ...

Identification and characterization of PorH, a new cell wall channel of Corynebacterium glutamicum (2005)

Hunten, P., Costa-Riu, N., Palm, D., Lottspeich, F., Benz, R.

Identification of Dll1 (Delta1) target genes during mouse embryogenesis using differential expression profiling (2005)

Machka, C., Kersten, A., Zobawa, M., Harder, A., Horsch, A., Halder, T., ...

Identification of coexpressed gene clusters in a comparative analysis of transcriptome and proteome in mouse tissues (2005)

Mijalski, T., Harder, A., Halder, T., Kersten, M., Horsch, M., Strom, T. M., ...

Identification of fatty acid binding proteins as markers associated with the initiation and/or progression of renal cell carcinoma (2005)

Seliger, B., Lichtenfels, R., Atkins, D., Bukur, J., Halder, T., Kersten, M., ...

Nuclear events in apoptosis: From the nuclear pore to proteomics (2005)

Tabbert, A., Patre, M., Kellermann, J., Lottspeich, F., Ferrando-May, E.

PorH a new channel-forming protein present in the cell wall of Corynebacterium efficiens and Corynebacterium callunae (2005)

Hunten, P., Schiffler, B., Lottspeich, F., Benz, R.

The highly abundant protein Ag-Ibp55 from Ascaridia galli represents a novel type of lipid-binding proteins (2005)

Jordanova, R., Radoslavov, G., Fischer, P., Torda, A., Lottspeich, F., Boteva, R., ...

The pyruvate kinase of Stigmatella aurantiaca is an indole binding protein and essential for development (2005)

Stamm, I., Lottspeich, F., Plaga, W.

Induction of apoptosis by a hepatocyte conditioned medium (2004)

Bresgen, N., Rolinek, R., Hochleitner, E., Lottspeich, F., Eckl, P. M.

Isolation and characterization of an outer membrane protein of Chlorobium tepidum (2004)

Aivaliotis, M., Neofotistou, E., Remigy, H. W., Tsimpinos, G., Lustig, A., Lottspeich, F., ...

The 2.0 angstrom crystal structure and substrate specificity of the KDEL-tailed cysteine endopeptidase functioning in programmed cell death of Ricinus communis endosperm (2004)

Than, M. E., Helm, M., Simpson, D. J., Lottspeich, F., Huber, R., Gietl, C.

Determination of the stoichiometry of protein complexes using liquid chromatography with fluorescence and mass spectrometric detection of fluorescently labeled proteolytic peptides (2004)

Hochleitner, E. O., Sondermann, P., Lottspeich, F.

Functional interaction in establishment of ribosomal integrity between small subunit protein rpS6 and translational regulator rpL10/Grc5p (2004)

Pachler, K., Karl, T., Kolmann, K., Mehlmer, N., Eder, M., Loeffler, M., ...

Purification and partial amino acid sequences of the enzyme vinorine synthase involved in a crucial step of ajmaline biosynthesis (2004)

Gerasimenko, I., Ma, X. Y., Sheludko, Y., Mentele, R., Lottspeich, F., Stockigt, J.

Identification of cell surface determinants in Candida albicans reveals Tsa1p, a protein differentially localized in the cell (2003)

Urban, C., Sohn, K., Lottspeich, F., Brunner, H., Rupp, S.

To identify cell surface proteins of Candida albicans, the predominant fungal pathogen in humans, we have established an approach using a membrane impermeable biotin derivative in combination with...

Human IgG1/IgG3 cryoglobulin suggesting lack of allelic exclusion (2003)

Mohanty, S., Weiner, S. M., Mentele, R., Vaith, P., Lottspeich, F., Illges, H.

Immunoglobulins undergoing cold-dependent precipitation are known as cryoglobulins. A type I cryoglobulin after Brouet et al. from serum of a patient with severe cutaneous vasculitis and...

Analysis of the quorum-sensing regulon of the opportunistic pathogen Burkholderia cepacia H111 by proteomics (2003)

Riedel, K., Arevalo-Ferro, C., Reil, G., Gorg, A., Lottspeich, F., Eberl, L.

Burkholderia cepacia H111, an important pathogen for persons suffering from cystic fibrosis, employs a quorum-sensing (QS) system, cep, to control expression of virulence factors as well as the...

Inactivation of the selB gene in Methanococcus maripaludis: Effect on synthesis of selenoproteins and their sulfur- containing homologs (2003)

Rother, M., Mathes, I., Lottspeich, F., Bock, A.

The genome of Methanococcus maripaludis harbors genes for at least six selenocysteine-containing proteins and also for homologs that contain a cysteine codon in the position of the UGA selenocysteine...

Identification of teleost Thy-1 and association with the microdornain/lipid raft reggie proteins in regenerating CNS axons (2003)

Deininger, S. O., Rajendran, L., Lottspeich, F., Przybylski, M., Illges, H., Stuermer, C. A. O., ...

During regeneration, retinal ganglion cell axons in fish upregulate a cell surface protein that is recognized by the monoclonal antibody (mAB) M802. M802 antigen appeared to be linked to the...

Lic16A of Clostridium thermocellum, a non-cellulosomal, highly complex endo-beta-1, 3-glucanase bound to the outer cell surface (2003)

Fuchs, K. P., Zverlov, V. V., Velikodvorskaya, G. A., Lottspeich, F., Schwarz, W. H.

Clostridium thermocellum produces one major beta-1,3-glucanase. Genomic DNA fragments containing the gene were cloned from two strains, DSM1237(T) (6848 bp) and F7 (9766 bp). Overlapping sequences...

Isolation, characterization and electron microscopic single particle analysis of the NADH : ubiquinone oxidoreductase (complex I) from the hyperthermophilic eubacterium Aquifex aeolicus (2003)

Peng, G. H., Fritzsch, G., Zickermann, V., Schaagger, H., Mentele, R., Lottspeich, F., ...

The proton-translocating NADH:ubiquinone oxidoreductase (complex I) has been purified from Aquifex aeolicus, a hyperthermophilic eubacterium of known genome sequence. The purified detergent...

A novel docking site on Mediator is critical for activation by VP16 in mammalian cells (2003)

Mittler, G., Stuhler, T., Santolin, L., Uhlmann, T., Kremmer, E., Lottspeich, F., ...

An exosome-like complex in Sulfolobus solfataricus (2003)

Evguenieva-Hackenberg, E., Walter, P., Hochleitner, E., Lottspeich, F., Klug, G.

Characterisation of apoptotic nuclear signaling pathways by proteomics (2003)

Tabbert, A., Kellermann, J., Lottspeich, F., Ferrando-May, E.

Identification of an anion-specific channel in the cell wall of the Gram-positive bacterium Corynebacterium glutamicum (2003)

Costa-Riu, N., Maier, E., Burkovski, A., Kramer, R., Lottspeich, F., Benz, R.

Identification of cell surface determinants in Candida albicans. (2003)

Urban, C., Sohn, K., Lottspeich, F., Schweikert, M., Brunner, H., Rupp, S.

Identification of markers for the selection of patients undergoing renal cell carcinoma-specific immunotherapy (2003)

Seliger, B., Menig, M., Lichtenfels, R., Atkins, D., Bukur, J., Halder, T. M., ...

Taming of a poison: Biosynthesis of the NiFe-hydrogenase cyanide ligands (2003)

Reissmann, S., Hochleitner, E., Wang, H. F., Paschos, A., Lottspeich, F., Glass, R. S., ...

A gene that encodes a product with similarity to dioxygenases is highly expressed in teliospores of Ustilago maydis (2002)

Lottspeich, F., Kämper, J.

Purification and partial amino acid sequences of an esterase from tomato (2002)

Stuhlfelder, C., Lottspeich, F., Mueller, M. J.

Screening of 18 suspension plant cell cultures of taxonomically distant species revealed that a methyl jasmonate hydrolysing enzyme activity (0.21-5.67 pkat/mg) occurs in all species so far analysed....

Nowa, a novel protein with minicollagen Cys-rich domains, is involved in nematocyst formation in Hydra (2002)

Engel, U., Oezbek, S., Engel, R., Petri, B., Lottspeich, F., Holstein, T. W.

The novel protein Nowa was identified in nematocysts, explosive organelles of Hydra, jellyfish, corals and other Cnidaria. Biogenesis of these organelles is complex and involves assembly of proteins...

Divergent members of a soybean (Glycine max L.) 4-coumarate : coenzyme A ligase gene family - Primary structures, catalytic properties, and differential expression (2002)

Lindermayr, C., Mollers, B., Fliegmann, J., Uhlmann, A., Lottspeich, F., Meimberg, H., ...

4-Coumarate:CoA ligase (4CL) is involved in the formation of coenzyme A thioesters of hydroxycinnamic acids that are central substrates for subsequent condensation, reduction, and transfer reactions...

Identification and characterization of a novel human plant pathogenesis-related protein that localizes to lipid-enriched microdomains in the Golgi complex (2002)

Eberle, H. B., Serrano, R. L., Füllekrug, J., Schlosser, A., Lehmann, W. D., Lottspeich, F., ...

Group 1 of plant pathogenesis-related proteins (PR-1) and a variety of related mammalian proteins constitute a superfamily of proteins that share structural similarities. Little is known about their...

Untitled (2002)

Lottspeich, F.

Novel basic-region helix-loop-helix transcription factor (AnBH1) of Aspergillus nidulans counteracts the CCAAT-binding complex AnCF in the promoter of a penicillin biosynthesis gene (2002)

Caruso, M. L., Litzka, O., Martic, G., Lottspeich, F., Brakhage, A. A.

Cis-acting CCAAT elements are found frequently in eukaryotic promoter regions. Many of the genes containing such elements in their promoters are regulated by a conserved multimeric CCAAT- binding...

A gene that encodes a product with similarity to dioxygenases is highly expressed in teliospores of Ustilago maydis (2002)

Lottspeich, F., Kamper, J.

The phytopathogenic basidiomycete Ustilago maydis produces sexual teliospores only after infection of its host plant, maize. To investigate the process of spore formation, we have isolated Ssp1, a...

A catalase-peroxidase from a newly isolated thermoalkaliphilic Bacillus sp with potential for the treatment of textile bleaching effluents (2001)

Gudelj, M., Fruhwirth, G. O., Paar, A., Lottspeich, F., Robra, K. H., Cavaco-Paulo, A., ...

A new thermoalkaliphilic bacterium was isolated from a textile wastewater drain and identified as a new Bacillus sp. (Bacillus SF). Because of its high pH stability and thermostability, a...

Two glucosyltransferases are involved in detoxification of benzoxazinoids in maize (2001)

Von Rad, U., Huttl, R., Lottspeich, F., Gierl, A., Frey, M.

Benzoxazinoids are major compounds involved in chemical defence in grasses. These toxins are stored in the vacuole as glucosides. Two glucosyltransferases, BX8 and BX9, that catalyse this last step...

Maize endosperm secretes a novel antifungal protein into adjacent maternal tissue (2001)

Maitz, M., O'Connell, T., Santandrea, G., Tierens, K., ...

A role for Ctr9p and Paf1p in the regulation G1 cyclin expression in yeast (1999)

Koch, C, Wollmann, P, Dahl, M, Lottspeich, F

The role of tricorn protease and its aminopeptidase-interacting factors in cellular protein degradation (1998)

Tamura, N., Lottspeich, F., Baumeister, W., Tamura, T.

Tricorn protease was previously described as the core enzyme of a modular proteolytic system displaying multicatalytic activity. Here we elucidate the mode of cooperation between Tricorn and its...

Genetic complexity, structure and characterization of highly active bovine intestinal alkaline phosphatases (1998)

Müller, R, Lottspeich, F, Hölke, W, Millan, J CORA

Tricorn protease - the core of a modular proteolytic system (1996)

Tamura, T., Tamura, N., Cejka, Z., Hegerl, R., Lottspeich, F., Baumeister, W.

Large macromolecular assemblies have evolved as a means of compartmentalizing reactions in organisms lacking membrane-bounded compartments. A tricorn-shaped protease was isolated from the archaeon...

Effects of major-histocompatibility-complex-encoded subunits on the peptidase and proteolytic activities of human 20s proteasomes - cleavage of proteins and antigenic peptides (1996)

Ehring, B., Meyer, T. H., Eckerskorn, C., Lottspeich, F., Tampe, R.

The proteasome is responsible for the non-lysosomal degradation of misfolded, transient, or ubiquitin-tagged proteins. This fact and the identification of two...

Tricorn protease (tri) interacting factor 1 from thermoplasma acidophilum is a proline iminopeptidase (1996)

Tamura, T., Tamura, N., Lottspeich, F., Baumeister, W.

Tricorn protease (TRI), a high molecular mass complex from the archaeon T. acidophilum, forms the core of a modular proteolytic system; upon interacting with low molecular mass factors intrinsic...

Characterization of the single-strand-specific BPV-1 origin binding protein, SPSF I, as the HeLa Pur alpha factor (1996)

Jurk, M, Weissinger, F, Lottspeich, F, Schwarz, U, Winnacker, EL

Different protein patterns derived from follicular fluid of mature and immature human follicles (1996)

Spitzer, D., Murach, K.F., Lottspeich, F., Staudach, A., Illmensee, K.

The purpose of our study was to compare the protein patterns originating from fluids of mature and immature human follicles in order to gain further insight into their biochemical composition. A...

The first characterization of a eubacterial proteasome - the 2os complex of rhodococcus (1995)

Tamura, T., Nagy, I., Lupas, A., Lottspeich, F., Cejka, Z., Schoofs, G., ...

Background: The 26S proteasome is the central protease of the ubiquitin-dependent pathway of protein degradation. The proteolytic core of the complex is formed by the 20S proteasome, a...

The first characterization of a eubacterial proteasome - the 20S complex of Rhodococcus (1995)

Nagy, I, Lupas, A, Lottspeich, F, Cejka, Z, Schoofs, G, ...

Background: The 26S proteasome is the central protease of the ubiquitin-dependent pathway of protein degradation. The proteolytic core of the complex is formed by the 20S proteasome, a...

Characterization of relevant membrane antigens by two-dimensional immunoblot and n-terminal sequence analysis in patients with myocarditis (1995)

Pankuweit, S., Lottspeich, F., Maisch, B.

In myocarditis an antigen-specific immune response to cardiac epitopes has been demonstrated by several investigators. In 25 patients with histologically proven myocarditis, autoantibodies to cardiac...

Existence of a molecular ruler in proteasomes suggested by analysis of degradation products (1994)

Wenzel, T., Eckerskorn, C., Lottspeich, F., Baumeister, W.

Analysis of the degradation products from two proteins, the insulin B-chain and human hemoglobin, generated by archaebacterial Thermoplasma acidophilum 20 S proteasomes, revealed an unexpectedly...

Proteasomes from Dictyostelium discoideum: characterization of structure and function (1993)

Schauer, T. M., Nesper, M., Kehl, M., Lottspeich, F., Müller-Taubenberger, A., Gerisch, G., ...

We have isolated and purified 20 S proteasomes from Dictyostelium discoideum and characterized their proteolytic activities. Two-dimensional electrophoresis revealed 13 distinct spots. Affinity...

Ubiquitin found in the archaebacterium Thermoplasma acidophilum (1993)

Wolf, S., Lottspeich, F., Baumeister, W.

Systematic N-terminal sequencing of the low molecular weight proteins from Thermoplasma acidophilum separated by two-dimensional poly-acrylamide gel electrophoresis led to the discovery of a...

The DNA-dependent RNA-polymerase of Thermotoga maritima; characterisation of the enzyme and the DNA-sequence of the genes for the large subunits (1993)

Palm, P., Schleper, C., Arnold-Ammer, I., Holz, I., Meier, T., Lottspeich, F., ...

An improved purification procedure for Thermotoga maritima RNA-polymerase holoenzyme was developed. The enzyme is highly active with poly dAT or T7 phage DNA as template. DNA gyrase was found to be a...

Evidence for tyrosine-linked glycosaminoglycan in a bacterial surface protein (1992)

Peters, J., Rudolf, S., Oschkinat, H., Mengele, R., Sumper, M., Kellermann, J., ...

The S-layer protein of Acetogenium kivui was subjected to proteolysis with different proteases and several high molecular mass glycosaminoglycan peptides containing glucose, galactosamine and an...

Topology of the anion-selective porin Omp32 from Comamonas acidovorans (1992)

Gerbl-Rieger, S., Engelhardt, H., Peters, J., Kehl, M., Lottspeich, F., Baumeister, W.

Limited proteolysis experiments were performed with outer membranes from Comamonas acidovorans to probe the topology of its major protein component, the anion-selective porin Omp32. Proteinase K...

Primary structure of the Thermoplasma proteasome and its implications for the structure, function, and evolution of the multicatalytic proteinase (1992)

Zwickl, P., Grziwa, A., Pühler, G., Dahlmann, B., Lottspeich, F., Baumeister, W.

The proteasome or multicatalytic proteinase is a high molecular mass multisubunit complex ubiquitous in eukaryotes but also found in the archaebacterial proteasome is made of two different subunits...

Expression of functional Thermoplasma acidophilum proteasomes in Escherichia coli (1992)

Zwickl, P., Lottspeich, F., Baumeister, W.

The two genes encoding the constituent subunits of the Thermoplasma acidophilum proteasome were expressed in Escherichia coli yielding fully assembled molecules as shown by electron microscopy. The...

Isolation and cloning of Omp alpha, a coiled-coil protein spanning the periplasmic space of the ancestral eubacterium Thermotoga maritima (1992)

Engel, A. M., Cejka, Z., Lupas, A., Lottspeich, F., Baumeister, W.

We have discovered a new oligomeric protein component associated with the outer membrane of the ancestral eubacterium Thermotoga maritima. In electron micrographs, the protein, Omp alpha, appears as...

Nucleotide and derived amino acid sequences of the major porin of Comamonas acidovorans and comparison of porin primary structures (1991)

Gerbl-Rieger, S., Peters, J., Kellermann, J., Lottspeich, F., Baumeister, W.

The DNA sequence of the gene which codes for the major outer membrane porin (Omp32) of Comamonas acidovorans has been determined. The structural gene encodes a precursor consisting of 351 amino acid...

Cloning and sequencing of the gene encoding the large (alpha-) subunit of the proteasome from Thermoplasma acidophilum (1991)

Zwickl, P., Lottspeich, F., Dahlmann, B., Baumeister, W.

The gene encoding the alpha-subunit of the proteasome from the archaebacterium Thermoplasma acidophilum was cloned and sequenced. The gene encodes for a polypeptide with 233 amino acid residues and a...

An Unusual Large Protein Complex with Eight-fold Symmetry is a Major Cellular Component of Thermophilic Archaebacteria (1990)

Phipps, B. M., Alber, A., Stetter, K. O., Lottspeich, F., Baumeister, W.

Electron microscopy and image analysis reveal common principles of organization in two large protein complexes: groEL-type proteins and proteasomes (1990)

Zwickl, P., Pfeifer, G., Lottspeich, F., Kopp, F., Dahlmann, B., Baumeister, W.

In an attempt to settle the question of whether the multicatalytic proteinase or proteasome exist in all three kingdoms of life--eukaryotes, archaebacteria, and eubacteria--we have undertaken a...

S-layer protein gene of Acetogenium kivui: cloning and expression in Escherichia coli and determination of the nucleotide sequence (1989)

Peters, J., Peters, M., Lottspeich, F., Baumeister, W.

Acetogenium kivui is anaerobically growing thermophilic bacterium with a gram-positive type of cell wall structure. The outer surface is covered with a hexagonally packed surface (S) layer. The gene...

Molecular cloning, expression and regional distribution of rat ciliary neurotrophic factor (1989)

Stöckli, K. A., Lottspeich, F., Sendtner, Michael, Masiakowski, P., Carroll, Patrick, Götz, Rudolf, ...

CILIARY neurotrophic factor (CNTF) was originally characterized as a survival factor for chick ciliary neurons in vitro. More recently, it was shown to promote the survival of a variety of...

The Primary Structure of the HPI-Layer Polypeptide of Deinococcus radiodurans (1988)

Peters, J., Peters, M., Lottspeich, F., Schäfer, W., Cejka, Z., Baumeister, W.

Complete amino-acid-sequence of a functional unit from a molluscan hemocyanin (helix-pomatia) (1987)

Siegmund, S, Schneider, Hj, Linzen, B, Preaux, G, ...

Nucleotide sequence analysis of the gene encoding the Deinococcus radiodurans surface protein, derived amino acid sequence, and complementary protein chemical studies (1987)

Peters, J., Peters, M., Lottspeich, F., Schäfer, W., Baumeister, W.

The complete nucleotide sequence of the gene encoding the surface (hexagonally packed intermediate [HPI])-layer polypeptide of Deinococcus radiodurans Sark was determined and found to encode a...

F. Lottspeich

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