Erpenbeck, V.J., Fischer, I., Wiese, K., Schaumann, F., Schmiedl, A., Nassenstein, C., ...
Background: There is increasing interest in testing surfactant preparations for asthma therapy. Previously, Curosurf was demonstrated to increase inflammation in allergic asthmatics. So far, little...
Prolonged pro-inflammatory effects of ultrafine particles in the lung of allergic asthmatics (2009)
Schaumann, F., Dijkstra, D., Froemke, C., Windt, H., Karg, E., Mueller, M., ...
Hohlfeld, J.M., Schönfeld, K., Lavae-Mokhtari, M., Schaumann, F., Müller, M., Bredenbröker, D., ...
RATIONALE: Roflumilast, an investigational, targeted phosphodiesterase 4 inhibitor, reduces the in vitro and in vivo inflammatory activity of cells such as neutrophils, eosinophils, macrophages, and...
Schaumann, F., Müller, M., Braun, A., Luettig, B., Peden, B., Hohlfeld, J.M., ...
RATIONALE: Epidemiologic studies have shown that exacerbation of asthma is modulated by environmental endotoxin. High levels of endotoxin are associated with asthma symptoms and the current use of...
Schaumann, F., Borm, P.J.A., Herbrich, A., Knoch, J., Pitz, M., Schins, R.P.F., ...
Epidemiologic studies have shown an increased prevalence of allergic asthma in children living in a German smelter area (Hettstedt) compared with a cohort who live in a nonindustrialized area...