Feng Gao

Details der Publikationsliste

Zeitraum

1989 - 2010

Anzahl

246

Co-Autoren

Towards Generic Pattern Mining ⋆ (Extended Abstract) (2010)

Mohammed J. Zaki, Nilanjana De, Feng Gao, Nagender Parimi, Benjarath Phoophakdee, Joe Urban

Frequent Pattern Mining (FPM) is a very powerful paradigm which encompasses an entire class of data mining tasks. The specific tasks encompassed by FPM include the mining of increasingly complex and...

Generic Pattern Mining via Data Mining Template Library ⋆ (2010)

Mohammed J. Zaki, Nilanjana De, Feng Gao, Paolo Palmerini, Jeevan Pathuri, Benjarath Phoophakdee, ...

Abstract. Frequent Pattern Mining (FPM) is a very powerful paradigm for mining informative and useful patterns in massive, complex datasets. In this paper we propose the Data Mining Template Library,...

Common and Privatized: Conditions for Wise Management of Matsutake Mushrooms in Northwest Yunnan Province, China (2009)

Yang, Xuefei; Laboratory Of Biodiversity And Biogeography, Kunming Institute Of Botany, Chinese Academy Of Sciences; Laboratory Of Ethnobotany, Kunming Institute Of Botany, Chinese Academy Of Sciences, Wilkes, Andreas; World Agroforestry Centre (ICRAF), China Program; Awilkes@mail.kib.ac.cn, Yang, Yongping; Laboratory Of Biodiversity And Biogeography, Kunming Institute Of Botany, Chinese Academy Of Sciences; Laboratory Of Ethnobotany, Kunming Institute Of Botany, Chinese Academy Of Scienc, Xu, Jianchu; Laboratory Of Ethnobotany, Kunming Institute Of Botany, Chinese Academy Of Sciences; World Agroforestry Centre (ICRAF), China Program; Jxu@mail.kib.ac.cn, Geslani, Cheryl S; University Of Hawai'i At Manoa; Geslani@hawaii.edu, Yang, Xueqing; Laboratory Of Biodiversity And Biogeography, Kunming Institute Of Botany, Chinese Academy Of Sciences; Yangxueqing@mail.kib.a.cn, ...

Since Hardin’s (1968) paper on the "Tragedy of the Commons," property rights of common-pool resources have been a central concern for natural resource management scholars. Matsutake, a common-pool...

Complex embryos displaying bilaterian characters from Precambrian Doushantuo phosphate deposits, Weng'an, Guizhou, China (2009)

Chen, Jun-Yuan, Bottjer, David J., Li, Gang, Hadfield, Michael G., Gao, Feng, Cameron, Andrew R., ...

Three-dimensionally preserved embryos from the Precambrian Ediacaran Doushantuo Formation, Weng'an, Guizhou, southern China, have attracted great attention as the oldest fossil evidence yet found for...

Phase contrast synchrotron X-ray microtomography of Ediacaran (Doushantuo) metazoan microfossils: Phylogenetic diversity and evolutionary implications (2009)

Chen, Jun-Yuan, Bottjer, David J., Davidson, Eric H., Li, Gang, Gao, Feng, Cameron, R. Andrew, ...

Microfossils from the Ediacaran Weng’an Phosphate Member of the Doushantuo Formation (Guizhou Province, southern China) have received widespread attention. The Doushantuo, which overlies the...

A clinical evaluation of amlexanox oral adhesive pellicles in the treatment of recurrent aphthous stomatitis and comparison with amlexanox oral tablets: a randomized, placebo controlled, blinded, multicenter clinical trial (2009)

Meng, Wenxia, Dong, Yi, Liu, Jie, Wang, Zhi, Zhong, Xiaobo, Chen, Ruiyang, ...

Abstract Background Amlexanox has been developed as a 5 percent topical oral paste for the treatment of patients with recurrent aphthous stomatitis (RAS) in most European countries. However, it is...

e-learning技术与应用 (2009)

Feng Gao

通过学习,掌握电子学习的基本术语、知识,了解相关技术,掌握常用的课程制作技术和电子课程设计理论和方法。

Single Crystalline Cadmium Sulfide Nanowires with Branched Structure (2009)

Gao, Feng, Lu, Qingyi

n this article, we report the synthesis of branched single crystal CdS nanowires. This branched CdS nanostructure is prepared by a simple surfactant-directing method, which is of particular interest...

The Role of Antibody Polyspecificity and Lipid Reactivity in Binding of Broadly Neutralizing Anti-HIV-1 Envelope Human Monoclonal Antibodies 2F5 and 4E10 to Glycoprotein 41 Membrane Proximal Envelope Epitopes 1 (2008)

S. Munir Alam, Mildred Mcadams, David Boren, Michael Rak, Richard M. Scearce, Feng Gao, ...

Two neutralizing human mAbs, 2F5 and 4E10, that react with the HIV-1 envelope gp41 membrane proximal region are also polyspecific autoantibodies that bind to anionic phospholipids. To determine the...

A compatible exon-exon junction database for the identification of exon skipping events using tandem mass spectrum data (2008)

Mo, Fan, Hong, Xu, Gao, Feng, Du, Lin, Wang, Jun, Omenn, Gilbert S, ...

Abstract Background Alternative splicing is an important gene regulation mechanism. It is estimated that about 74% of multi-exon human genes have alternative splicing. High throughput tandem (MS/MS)...

Evaluation of On-Line Bradycardia Boundary Detectors from Neonatal Clinical Data (2008)

François Portet, Feng Gao, Jim Hunter, Somayajulu Sripada

Abstract—this paper aims at investigating different methods for the detection of the start and end of bradycardias in heart rate signal of premature babies. We present two methods based on a...

Evaluation of the LiTransit Kernel for BRDF Modeling (2008)

Feng Gao, Xiaowen Li, Alan Strahler, Crystal Schaaf

Kernel-driven bidirectional reflectance distribution function (BRDF) models are widely used in the description of BRDF properties of land types. To further improve the ability of kernel-driven...

An Accurate Registration Method for Large Object Surface Reconstruction from Range Image 502 (2008)

B. Jharia, S. Sarkar, R. P. Agarwal, Patricia Renault, Pirouz Bazargan-sabet, Fabio T. Wakabayashi, ...

Measuring the equivalent resistance of electrode filaments of tubular fluorescent lamps, during dimming operation

Phase-sensitive Manipulations of Squeezed Vacuum Field in an Optical Parametric Amplifier inside an Optical Cavity (2008)

Zhang, Jing, Ye, Chenguang, Gao, Feng, Xiao, Min

Squeezed vacuum field can be amplified or deamplified when it is injected, as the signal beam, into a phase-sensitive optical parametric amplifier (OPA) inside an optical cavity. The spectral...

A Hierarchical Trade-off Assessment Model and the Systematic Evaluation of Networked Systems (2008)

Feng Gao, Xinfeng Ye

In this abstract, a hierarchical trade-off assessment model for networked systems is presented that constructs from the perspectives of systematic objectives, network component requirements, along...

Metabolic, Endocrine and Genitourinary Pathobiology Fibronectin-�4�1 Integrin Interactions Regulate Metalloproteinase-9 Expression in Steatotic Liver Ischemia and Reperfusion (2008)

Carolina Moore, Xiu-da Shen, Feng Gao, Ronald W. Busuttil, Ana J. Coito

Ischemia/reperfusion injury is a major cause of the highly dysfunctional rate observed in marginal steatotic orthotopic liver transplantation. In this study, we document that the interactions between...

Oxygen microscopy by two-photon-excited phosphorescence (2008)

Finikova, Olga S., Lebedev, Artem Y., Aprelev, Alexey, Troxler, Thomas, Gao, Feng, Garnacho, Carmen, ...

High-resolution images of oxygen distributions in microheterogeneous samples are obtained by two-photon loser scanning microscopy (2P LSM), using a newly developed dendritic nanoprobe with internally...

Clustering Response-Stressor Relationships in Ecological Studies (2008)

Gao, Feng

This research is motivated by an issue frequently encountered in water quality monitoring and ecological assessment. One concern for researchers and watershed resource managers is how the biological...

Clustering Response-Stressor Relationships in Ecological Studies (2008)

Gao, Feng

This research is motivated by an issue frequently encountered in water quality monitoring and ecological assessment. One concern for researchers and watershed resource managers is how the biological...

A centralized gene-based HIV-1 vaccine elicits broad cross-clade cellular immune responses in rhesus monkeys (2008)

Santra, Sampa, Korber, Bette T., Muldoon, Mark, Barouch, Dan H., Nabel, Gary J., Gao, Feng, ...

One of the major challenges that must be met in developing an HIV-1 vaccine is devising a strategy to generate cellular immunity with sufficient breadth to deal with the extraordinary genetic...

Transfer of a large gene regulatory apparatus to a new developmental address in echinoid evolution (2008)

Gao, Feng, Davidson, Eric H.

Of the five echinoderm classes, only the modern sea urchins (euechinoids) generate a precociously specified embryonic micromere lineage that ingresses before gastrulation and then secretes the...

Comparison of Artificial Life Techniques for Market Simulation (2008)

Feng Gao, Student Member, G. Gutierrez-alcaraz, Gerald B. Sheble Fellow

Electricity industries worldwide are undergoing a period of profound upheaval. Conventional vertically integrated mechanism is replaced by a competitive market environment. A pure operating cost...

Summarizing Dive Computer Data: A Case Study in Integrating Textual and Graphical Presentations of Numerical Data (2008)

Somayajulu G Sripada, Feng Gao

Currently numerical data are most often presented graphically to human users. A recent study in the medical domain showed that under experimental conditions medical staff made better clinical...

Stochastic Partitioning Techniques for Reducing Routing Computational Effort (2008)

Feng Gao, M. E. Woodward

This paper presents some stochastic partitioning strategies with the objective of reducing computational effort of routing in networks. An objective function has been defined to measure the average...

A Dynamic Polling Scheme for the Network Monitoring Problem (2008)

Feng Gao, Jairo Gutierrez

Network monitoring is one of the most significant functions in network management. In order to measure network elements and services, normally a polling approach is used to help network professionals...

Combining Sequence and Time Series Expression Data to Learn Transcriptional Modules (2008)

Anshul Kundaje, Manuel Middendorf, Feng Gao, Chris Wiggins, Christina Leslie

Our goal is to cluster genes into transcriptional modules—sets of genes where similarity in expression is explained by common regulatory mechanisms at the transcriptional level. We want to learn...

Reduction of Large Training Set by Guided Progressive Sampling: Application to Neonatal Intensive Care Data (2008)

François Portet, Feng Gao, Jim Hunter, René Quiniou

Although large training sets are supposed to improve the performance of learning algorithms, there are limits to the volume of data such an algorithm can handle. To overcome this problem, we describe...

SUGI 31 Paper 187-31 Analyzing Multivariate Longitudinal Data Using SAS® (2008)

Feng Gao, Paul Thompson, Chengjie Xiong, J. Philip Miller

Multivariate longitudinal data provides a unique opportunity in studying the joint evolution of multiple response variables over time. Comparing to the traditional univariate longitudinal data, the...

A Model Set Based Object Segmentation Method Using Level Set Approach (2008)

Xun Wang, Zhigang Peng, Feng Gao, William G. Wee

Abstract. A novel approach for model set based object segmentation is described. The proposed method enables the using of a model set to guide the object segmentation. The object shape model...

Ori-Finder: A web-based system for finding oriCs in unannotated bacterial genomes (2008)

Gao, Feng, Zhang, Chun-Ting

Abstract Background Chromosomal replication is the central event in the bacterial cell cycle. Identification of replication origins ( oriC s) is necessary for almost all newly sequenced bacterial...

Interactive Effects of Elevated CO2 and Cotton Cultivar on Tri-Trophic Interaction of Gossypium hirsutum, Aphis gossyppii, and Propylaea japonica (2008)

Feng Gao, San-Rong Zhu, Yu-Cheng Sun, Li Du, Meghan Parajulee, Le Kang, ...

Information on the effects of enriched CO2 on both the chemical composition of plants and the consequences of such changes for performance of a herbivore and its predator is an important first step...

Numerical investigations of wave overtopping at coastal structures (2008)

Ingram, David M., Gao, Feng, Causon, Derek M., Mingham, Clive G., Troch, Peter

Full-text of this article is not available in this e-prints service. This article was originally published following peer-review in Coastal engineering, published by and copyright Elsevier.

Numerical investigations of wave overtopping at coastal structures (2008)

Ingram, David M., Gao, Feng, Causon, Derek M., Mingham, Clive G., Troch, Peter

Full-text of this article is not available in this e-prints service. This article was originally published following peer-review in Coastal engineering, published by and copyright Elsevier.

Origins of Replication in Sorangium cellulosum and Microcystis aeruginosa (2008)

Gao, Feng, Zhang, Chun-Ting

The genome of Sorangium cellulosum has recently been completely sequenced, and it is the largest bacterial genome sequenced so far. In their report, Schneiker et al. (in Complete genome sequence of...

BMC Bioinformatics BioMed Central Methodology article (2008)

Fan Mo, Xu Hong, Feng Gao, Lin Du, Jun Wang, Gilbert S Omenn, ...

A compatible exon-exon junction database for the identification of exon skipping events using tandem mass spectrum data

Optimal Fault-Tolerant Routing in Hypercubes Using Extended Safety Vectors (2007)

Jie Wu, Feng Gao, Zhongcheng Li, Yinghua Min

1 Reliable communication in cube-based multicomputers using the extended safety vector concept is studied in this paper. In our approach, each node in a cube-based multicomputer of dimension n is...

Challenges in Providing Management Strategies for Networked Systems (2007)

Feng Gao, Student Member, Jairo Gutierrez

Abstract--This paper presents a review of current management strategies for networked systems, followed by a discussion of the issues involved in providing Quality of Service guaranteed management...

by (2007)

Grace Wahba, Donald R. Johnson, Feng Gao, Jianjian Gong

Adaptive tuning of numerical weather prediction models: Part I: randomized GCV and related methods in three and four dimensional data assimilation

Generic Pattern Mining via Data Mining Template Library (2007)

Nilanjana De, Feng Gao, Paolo Palmerini, Nagender Parimi, Jeevan Pathuri, Benjarath Phoophakdee, ...

Frequent Pattern Mining (FPM) is a very powerful paradigm for mining informative and useful patterns in massive, complex datasets. In this paper we propose the Data Mining Template Library, a...

Crystal structures of high affinity human T-cell receptors bound to peptide major histocompatibility complex reveal native diagonal binding geometry (2007)

Sami, Malkit, Rizkallah, Pierre J., Dunn, Steve, Molloy, Peter, Moysey, Ruth, Vuidepot, Annelise, ...

Naturally selected T-cell receptors (TCRs) are characterised by low binding affinities, typically in the range 1–100 µM. Crystal structures of syngeneic TCRs bound to peptide major...

Concurrent mutations in six amino acids in {beta}-glucuronidase improve its thermostability (2007)

Xiong, Ai-Sheng, Peng, Ri-He, Cheng, Zong-Ming, Li, Yi, Liu, Jin-Ge, Zhuang, Jing, ...

To achieve a thermostable β-glucuronidase (GUS) and identify key mutation sites, we applied in vitro directed evolution strategy through DNA shuffling and obtained a highly thermostable mutant GUS...

DoriC: a database of oriC regions in bacterial genomes (2007)

Gao, Feng, Zhang, Chun-Ting

Summary: Replication origins (oriCs) of bacterial genomes currently available in GenBank have been predicted by using a systematic method comprising the Z-curve analysis for nucleotide distribution...

The development of a Cartesian cut cell method for incompressible viscous flows (2007)

Gao, Feng, Ingram, David M., Causon, Derek M., Mingham, Clive G.

Full-text of this article is not available in this e-prints service. This article was originally published following peer-review in the International journal for numerical methods in fluids,...

The development of a Cartesian cut cell method for incompressible viscous flows (2007)

Gao, Feng, Ingram, David M., Causon, Derek M., Mingham, Clive G.

Full-text of this article is not available in this e-prints service. This article was originally published following peer-review in the International journal for numerical methods in fluids,...

Antigenicity and immunogenicity of HIV-1 consensus subtype B envelope glycoproteins (2007)

Kothe, Denise L., Decker, Julie M., Li, Yingying, Weng, Zhiping, Bibollet-Ruche, Frederic, Zammit, Kenneth P., ...

“Centralized” (ancestral and consensus) HIV-1 envelope immunogens induce broadly cross-reactive T cell responses in laboratory animals; however, their potential to elicit cross-reactive...

Single molecule study on lipid vesicles and proteins by confocal microscopy (2007)

Gao, Feng

Single molecule spectroscopy allows one to directly obtain the distributions of properties and therefore it is very useful in studying heterogeneous chemical and biological systems. This thesis...

Preparation, Polymerization, and Characterization of Sugar-based Microemulsion Glasses (2007)

Gao, Feng

Sugar-based microemulsion glasses are novel non-aqueous self-assemblies, which extend microemulsions from their liquid state to their solid state. This new type of microemulsion is optically clear...

Synthesis of aminoglycoside derivatives to combat bacterial resistance (2007)

Gao, Feng

Aminoglycosides are broad spectrum antibiotics that act by binding to 16S rRNA of bacteria. The wide spread of aminoglycoside resistance threatens the use of these important medicines. Two general...

MANUFACTURABILITY AWARE DESIGN Doctoral Comittee: (2007)

Jie Yang, Youngmin Kim, Aseem Agarwal, Donwoo Lee, Feng Gao, Feng Wang

My sincere gratitude to Professor Dennis Sylvester for providing me the opportu-nity to study at the University of Michigan. Without his vision, encouragement and continuous support, this...

Synthesis of aminoglycoside derivatives to combat bacterial resistance (2007)

Gao, Feng

Aminoglycosides are broad spectrum antibiotics that act by binding to 16S rRNA of bacteria. The wide spread of aminoglycoside resistance threatens the use of these important medicines. Two general...

Swim training sensitizes myocardial response to insulin: Role of Akt-dependent eNOS activation (2007)

Zhang, Quan-Jiang, Li, Qiu-Xia, Zhang, Hai-Feng, Zhang, Kun-Ru, Guo, Wen-Yi, Wang, Hai-Chang, ...

Objectives Physical activity has been well known to benefit heart function. The improved autonomic nervous activity is considered to be mainly responsible for this beneficial effect. However, the...

Cross-Subtype T-Cell Immune Responses Induced by a Human Immunodeficiency Virus Type 1 Group M Consensus Env Immunogen (2006)

Weaver, Eric A., Lu, Zhongjing, Camacho, Zenadio T., Moukdar, Fatiha, Liao, Hua-Xin, Ma, Ben-Jiang, ...

The genetic diversity among globally circulating human immunodeficiency virus type 1 (HIV-1) strains is a serious challenge for HIV-1 vaccine design. We have generated a synthetic group M consensus...

Insulin improves cardiomyocyte contractile function through enhancement of SERCA2a activity in simulated ischemia/reperfusion (2006)

Yu, Jie, Zhang, Hai-feng, Wu, Feng, Li, Qiu-xia, Ma, Heng, Guo, Wen-yi, ...

AIM: Insulin exerts anti-apoptotic effects in both cardiomyocytes and coronary endothelial cells following ischemia/reperfusion (I/R) via the Akt-endothelial nitric oxide synthase survival signal...

Streptococcal Toxic Shock Syndrome Caused by Streptococcus suis Serotype 2 (2006)

Jiaqi Tang, Changjun Wang, Youjun Feng, Weizhong Yang, Huaidong Song, Zhihai Chen, ...

Clinical description of a 2005 S. suis outbreak in China that affected over 200 individuals and initial characterization of the pathogenic isolates from affected pigs and humans.

Streptococcal Toxic Shock Syndrome Caused by Streptococcus suis Serotype 2 (2006)

Jiaqi Tang, Changjun Wang, Youjun Feng, Weizhong Yang, Huaidong Song, Zhihai Chen, ...

BackgroundStreptococcus suis serotype 2 (S. suis 2, SS2) is a major zoonotic pathogen that causes only sporadic cases of meningitis and sepsis in humans. Most if not all cases of Streptococcal toxic...

Stress analysis in a layered aortic arch model under pulsatile blood flow (2006)

Gao, Feng, Watanabe, Masahiro, Matsuzawa, Teruo

Abstract Background Many cardiovascular diseases, such as aortic dissection, frequently occur on the aortic arch and fluid-structure interactions play an important role in the cardiovascular system....

Environmental Controls on the Taphonomy of Phosphatized Animals and Animal Embryos from the Neoproterozoic Doushantuo Formation, Southwest China (2006)

STEPHEN Q. DORNBOS, DAVID J. BOTTJER, JUN-YUAN CHEN, FENG GAO, PAOLA OLIVERI, CHIA-WEI LI

Phosphatized animals and animal embryos of the Neoproterozoic Doushantuo Formation of Southwest China provide what is likely the earliest fossil evidence for animals, including bilaterians. This...

Further Results on Active Magnetic Bearing Control with Input Saturation (2006)

Mazenc, Frederic, De Queiroz, Marcio S., Malisoff, Michael, Gao, Feng

We study the low-bias stabilization of active magnetic bearings (AMBs) subject to voltage saturation based on a recently proposed model for the AMB switching mode of operation. Using a...

An Alternative and Effective HIV Vaccination Approach Based on Inhibition of Antigen Presentation Attenuators in Dendritic Cells (2006)

Xiao-Tong Song, Kevin Evel-Kabler, Lisa Rollins, Melissa Aldrich, Feng Gao, Xue F. Huang, ...

Si-Yi Chen and colleagues describe a possible alternative strategy for HIV vaccination in mice involving suppressor of cytokine signaling (SOCS) in dendritic cells.

An Alternative and Effective HIV Vaccination Approach Based on Inhibition of Antigen Presentation Attenuators in Dendritic Cells (2006)

Xiao-Tong Song, Kevin Evel-Kabler, Lisa Rollins, Melissa Aldrich, Feng Gao, Xue F. Huang, ...

Background Current efforts to develop HIV vaccines that seek to stimulate immune responses have been disappointing, underscoring the inability of natural immune responses to control HIV-1 infection....

Vasculoprotective effect of insulin in the ischemic/reperfused canine heart: Role of Akt-stimulated NO production (2006)

Ma, Heng, Zhang, Hai-Feng, Yu, Lu, Zhang, Quan-Jiang, Li, Jia, Huo, Jian-Hua, ...

Objectives: The objectives of this study were to investigate the vasculoprotective effects of glucose–insulin–potassium (GIK) on ischemia/reperfusion-induced coronary endothelial functional...

GC-Profile: a web-based tool for visualizing and analyzing the variation of GC content in genomic sequences (2006)

Gao, Feng, Zhang, Chun-Ting

In order to understand the evolution, structure and function of genomes, it is important to know the general compositional features of DNA sequences. Based on the quadratic divergence, a new...

Cloning of an H+-PPase gene from Thellungiella halophila and its heterologous expression to improve tobacco salt tolerance (2006)

Gao, Feng, Gao, Qiang, Duan, XiaoGuang, Yue, GuiDong, Yang, AiFang, Zhang, JuRen

An H+-pyrophosphatase (PPase) gene named TsVP involved in basic biochemical and physiological mechanisms was cloned from Thellungiella halophila. The deduced translation product has similar...

Directed evolution of human T cell receptor CDR2 residues by phage display dramatically enhances affinity for cognate peptide-MHC without increasing apparent cross-reactivity (2006)

Dunn, Steven M., Rizkallah, Pierre J., Baston, Emma, Mahon, Tara, Cameron, Brian, Moysey, Ruth, ...

The mammalian α/β T cell receptor (TCR) repertoire plays a pivotal role in adaptive immunity by recognizing short, processed, peptide antigens bound in the context of a highly diverse family of...

Cloning of an H+-PPase gene from Thellungiella halophila and its heterologous expression to improve tobacco salt tolerance (2006)

Gao, Feng, Gao, Qiang, Duan, XiaoGuang, Yue, GuiDong, Yang, AiFang, Zhang, JuRen

An H+-pyrophosphatase (PPase) gene named TsVP involved in basic biochemical and physiological mechanisms was cloned from Thellungiella halophila. The deduced translation product has similar...

Cloning of an H+-PPase gene from Thellungiella halophila and its heterologous expression to improve tobacco salt tolerance (2006)

Gao, Feng, Gao, Qiang, Duan, XiaoGuang, Yue, GuiDong, Yang, AiFang, Zhang, JuRen

An H+-pyrophosphatase (PPase) gene named TsVP involved in basic biochemical and physiological mechanisms was cloned from Thellungiella halophila. The deduced translation product has similar...

Protein Arrays for Multidrug-resistance in Human Leukemia Cell Determination (2005)

Juan Du, Baoan Chen, Chunxiu Zhang, Xiaoxing Xu, Jian Cheng, Feng Gao, ...

A novel technique was developed, that was high throughput simultaneousscreening of multiple resistance protein expression based on a protein array system. Themethod combined the advantage of the...

Towards generic pattern mining (2005)

Mohammed J. Zaki, Nagender Parimi, Nilanjana De, Feng Gao, Benjarath Phoophakdee, Joe Urban, ...

Abstract. Frequent Pattern Mining (FPM) is a very powerful paradigm for mining informative and useful patterns in massive, complex datasets. In this paper we propose the Data Mining Template Library,...

PSIST: Indexing protein structures using suffix trees (2005)

Feng Gao, Mohammed J. Zaki

Approaches for indexing proteins, and for fast and scalable searching for structures similar to a query structure have important applications such as protein structure and function prediction,...

Defining transcriptional networks through integrative modeling of mRNA expression and transcription factor binding data (2004)

Gao, Feng, Foat, Barrett C, Bussemaker, Harmen J

Abstract Background Functional genomics studies are yielding information about regulatory processes in the cell at an unprecedented scale. In the yeast S. cerevisiae , DNA microarrays have not only...

Studies on the synthesis, characterization and properties of colossal magnetoresistive (CMR) materials (2004)

Gao, Feng

Metal oxides constitute an interesting class of materials with a wide range of properties. They exhibit a variety of phenomena such as ferromagnetism, ferroelectricity, and superconductivity. In the...

DEBLOCKING AND EMBEDDED CODING IN IMAGE COMMUNICATION SYSTEMS (2004)

GAO, FENG

This dissertation addresses two problems in image communication systems. The first problem is blocking effects reduction and the second problem is embedded coding. The problem of blocking effects...

Studies on the synthesis, characterization and properties of colossal magnetoresistive (CMR) materials (2004)

Gao, Feng, N/a

Metal oxides constitute an interesting class of materials with a wide range of properties. They exhibit a variety of phenomena such as ferromagnetism, ferroelectricity, and superconductivity. In the...

Trade-off analysis in monitoring IP networks (2004)

Gao, Feng

Restricted Item. Print thesis available in the University of Auckland Library or available through Inter-Library Loan. Efficiently monitoring the behaviours of IP networks is a formidable challenge...

Deblocking and embedded coding in image communication systems [electronic resource] / (2004)

Gao, Feng., OhioLINK Electronic Theses And Dissertations Center.

This dissertation addresses two problems in image communication systems. The first problem is blocking effects reduction and the second problem is embedded coding. The problem of blocking effects...

Studies on the synthesis, characterization and properties of colossal magnetoresistive (CMR) materials (2004)

Gao, Feng

Metal oxides constitute an interesting class of materials with a wide range of properties. They exhibit a variety of phenomena such as ferromagnetism, ferroelectricity, and superconductivity. In the...

Studies on the synthesis, characterization and properties of colossal magnetoresistive (CMR) materials (2004)

Gao, Feng

Metal oxides constitute an interesting class of materials with a wide range of properties. They exhibit a variety of phenomena such as ferromagnetism, ferroelectricity, and superconductivity. In the...

Studies on the synthesis, characterization and properties of colossal magnetoresistive (CMR) materials (2004)

Gao, Feng, N/a

Metal oxides constitute an interesting class of materials with a wide range of properties. They exhibit a variety of phenomena such as ferromagnetism, ferroelectricity, and superconductivity. In the...

Studies on the synthesis, characterization and properties of colossal magnetoresistive (CMR) materials (2004)

Gao, Feng

Metal oxides constitute an interesting class of materials with a wide range of properties. They exhibit a variety of phenomena such as ferromagnetism, ferroelectricity, and superconductivity. In the...

Studies on the synthesis, characterization and properties of colossal magnetoresistive (CMR) materials (2004)

Gao, Feng

Metal oxides constitute an interesting class of materials with a wide range of properties. They exhibit a variety of phenomena such as ferromagnetism, ferroelectricity, and superconductivity. In the...

Studies on the synthesis, characterization and properties of colossal magnetoresistive (CMR) materials (2004)

Gao, Feng, N/a

Metal oxides constitute an interesting class of materials with a wide range of properties. They exhibit a variety of phenomena such as ferromagnetism, ferroelectricity, and superconductivity. In the...

Studies on the synthesis, characterization and properties of colossal magnetoresistive (CMR) materials (2004)

Gao, Feng

Metal oxides constitute an interesting class of materials with a wide range of properties. They exhibit a variety of phenomena such as ferromagnetism, ferroelectricity, and superconductivity. In the...

Comparison of various algorithms for recognizing short coding sequences of human genes (2004)

Gao, Feng, Zhang, Chun-Ting

Motivation: Since the early eighties of the twentieth century, there has been great progress in the development of computational gene-finding algorithms. Some problems, however, have not yet been...

Comparison of various algorithms for recognizing short coding sequences of human genes (2004)

Gao, Feng, Zhang, Chun-Ting

Motivation: Since the early 1980s of the twentieth century, there has been great progress in the development of computational gene-finding algorithms. Some problems, however, have not yet been solved...

Comparison of various algorithms for recognizing short coding sequences of human genes (2004)

Gao, Feng, Zhang, Chun-Ting

Motivation: Since the early eighties of the twentieth century, there has been great progress in the development of computational gene-finding algorithms. Some problems, however, have not yet been...

BMC Bioinformatics BioMed Central (2004)

Feng Gao, Barrett C Foat, Harmen J Bussemaker

Research article Defining transcriptional networks through integrative modeling of mRNA expression and transcription factor binding data

Helicobacter pylori stimulates host cyclooxygenase-2 gene transcription: critical importance of MEK/ERK-dependent activation of USF1/-2 and CREB transcription factors (2003)

Juttner,Stefan, Cramer,Thorsten, Wessler,Silja, Walduck,Anna, Gao,Feng, Schmitz,Frank, ...

Cyclooxygenase-2 (COX-2) represents the inducible key enzyme of arachidonic acid metabolism and contributes to the pathogenesis of gastroduodenal ulcers and gastric cancer. Helicobacter pylori...

On-Line Monitor Design of Finite-State Machines (2003)

Gao, Feng, Hayes, John P.

On-line monitoring is a useful technique for ensuring system reliability. By continuously supervising the system's operation, a wide range of problems, such as physical defects, transient faults and...

Consistency of MODIS surface bidirectional reflectance distribution function and albedo retrievals: 2. Validation (2003)

Liang, Shunlin, Lucht, Wolfgang, Jin, Yufang, Schaaf, Crystal B., Woodcock, Curtis E., Gao, Feng, ...

The evaluation of the first available satellite-based global albedo product at 1-km resolution is essential for its application in climate studies. We evaluate the accuracy of the Moderate-Resolution...

Consistency of MODIS surface bidirectional reflectance distribution function and albedo retrievals: 2. Validation (2003)

Liang, Shunlin, Lucht, Wolfgang, Jin, Yufang, Schaaf, Crystal B., Woodcock, Curtis E., Gao, Feng, ...

The evaluation of the first available satellite-based global albedo product at 1-km resolution is essential for its application in climate studies. We evaluate the accuracy of the Moderate-Resolution...

Design and analysis of post-fusion 6-helix bundle of heptad repeat regions from Newcastle disease virus F protein (2003)

Zhu, Jieqing, Li, Pengyun, Wu, Tinghe, Gao, Feng, Ding, Yi, Zhang, Catherine W.-H., ...

Fusion of paramyxovirus to the cell involves receptor binding of the HN glycoprotein and a number of conformational changes of F glycoprotein. The F protein is expressed as a homotrimer on the virus...

ACRONYMS 1 OP Optimal (2003)

Jie Wu, Feng Gao, Zhongcheng Li, Yinghua Min, Subop Sub-optimal

Abstract—We propose a new coding method of limited global fault information in an-cube. First, each node collects precise fault information within distance-, and then fault information about nodes...

Human anti-{beta}-amyloid antibodies block {beta}-amyloid fibril formation and prevent {beta}-amyloid-induced neurotoxicity (2003)

Du, Yansheng, Wei, Xing, Dodel, Richard, Sommer, Norbert, Hampel, Harald, Gao, Feng, ...

The accumulation of β-amyloid (Aβ) in neuritic plaques is thought to be causative for the progression of Alzheimer's disease (AD). Recently, both active immunization and passive administration of...

Design and analysis of post-fusion 6-helix bundle of heptad repeat regions from Newcastle disease virus F protein (2003)

Zhu, Jieqing, Li, Pengyun, Wu, Tinghe, Gao, Feng, Ding, Yi, Zhang, Catherine W.-H., ...

Fusion of paramyxovirus to the cell involves receptor binding of the HN glycoprotein and a number of conformational changes of F glycoprotein. The F protein is expressed as a homotrimer on the virus...

Human anti-{beta}-amyloid antibodies block {beta}-amyloid fibril formation and prevent {beta}-amyloid-induced neurotoxicity (2003)

Du, Yansheng, Wei, Xing, Dodel, Richard, Sommer, Norbert, Hampel, Harald, Gao, Feng, ...

The accumulation of β‐amyloid (Aβ) in neuritic plaques is thought to be causative for the progression of Alzheimer’s disease (AD). Recently, both active immunization and passive...

Human anti-{beta}-amyloid antibodies block {beta}-amyloid fibril formation and prevent {beta}-amyloid-induced neurotoxicity (2003)

Du, Yansheng, Wei, Xing, Dodel, Richard, Sommer, Norbert, Hampel, Harald, Gao, Feng, ...

The accumulation of β-amyloid (Aβ) in neuritic plaques is thought to be causative for the progression of Alzheimer's disease (AD). Recently, both active immunization and passive administration of...

First operational BRDF, albedo nadir reflectance products from MODIS (2002)

Schaaf, Crystal B, Gao, Feng, Strahler, Alan H, Lucht, Wolfgang, Li, Xiaowen, Tsang, Trevor, ...

With the launch of NASA's Terra satellite and the MODerate Resolution Imaging Spectroradiometer (MODIS), operational Bidirectional Reflectance Distribution Function (BRDF) and albedo products are now...

p38 MAPK inhibition reduces myocardial reperfusion injury via inhibition of endothelial adhesion molecule expression and blockade of PMN accumulation (2002)

Gao, Feng, Yue, Tian-Li, Shi, Dong-Wei, Christopher, Theodore A, Lopez, Bernard L, Ohlstein, Eliot H, ...

Background: In vitro evidence suggests that the p38 mitogen-activated protein kinase (p38 MAPK) plays a crucial role in PMN activation and inflammatory cytokine production. However, the effect of p38...

Precambrian animal diversity: Putative phosphatized embryos from the Doushantuo Formation of China (2000)

Chen, Jun-Yuan, Oliveri, Paola, Li, Chia-Wei, Zhou, Gui-Qing, Gao, Feng, Hagadorn, James W., ...

Putative fossil embryos and larvae from the Precambrian phosphorite rocks of the Doushantuo Formation in Southwest China have been examined in thin section by bright field and polarized light...

Misalignment tolerance in a 100 nm t-gate recessed-channel si nmosfet /--Feng Gao, B.S. (2000)

Gao, Feng.

Thesis (M.S. in Electrical Engineering)--Louisiana Tech University, November 2000.

Kinetics of laser chemical vapor deposition of carbon and refractory metals /--by Feng Gao, B.S. (2000)

Gao, Feng.

Thesis (Ph. D. in Manufacturing Systems Engineering)--Louisiana Tech University, November 2000.

Contributors (1999)

A. H. Strahler, J. -p. Muller, Modis Science, Team Members, Alan H. Strahler, Wolfgang Lucht, ...

2 The MODIS BRDF/Albedo product combines registered, multidate, multiband, atmo-spherically corrected surface re ectance data from the MODIS and MISR instruments to t a Bidirectional Re ectance...

Spectroscopic studies of multiheme proteins / (1997)

Gao, Feng.

Thesis (Ph. D.)--University of New Mexico, 1997.

A scale model of the through-casing resistivity measurement /--by Feng Gao. (1996)

Gao, Feng.

Degree granted by Dept. of Electrical and Computer Engineering, Cullen College of Engineering.

Molecular Cloning and Analysis of Functional Envelope Genes from Human Immunodeficiency Virus Type 1 Sequence (1995)

Subtypes A Through G, Feng Gao, Sandra G. Morrison, David L. Robertson, Charlotte L. Thornton, Stevenson Craig, ...

Present knowledge of human immunodeficiency virus type 1 (HIV-1) envelope immunobiology has been derived almost exclusively from analyses of subtype B viruses, yet such viruses represent only a...

The effectiveness of ultraviolet irradiation in reducing salmonellae on eggs and in egg facilities /--by Feng Gao. (1993)

Gao, Feng, University Of Maryland At College Park.--Dept. Of Engineering, Agriculture.

Thesis research directed by Dept. of Engineering, Agriculture.

On Combining Data from Multiple Sources with Unknown Relative Weights (1993)

Feng Gao, Feng Gao

The problem of using the "direct" variational methods in a statistical model that merges data from different sources with unknown relative weights is considered. To carry out this merging...

Theoretical and numerical investigations of scalar fields in isotropic turbulence / (1990)

Gao, Feng.

Thesis (Ph. D.)--State University of New York at Stony Brook, 1990.

Length heterogeneity in rat salivary gland {alpha}2{micro} globulin mRNAs: multiple splice-acceptors and polyadenylation sites (1989)

Gao, Feng, Endo, Hideya, Yamamoto, Mikio

Rat α2μ globulins are coded for by a family of about 25 structurally related genes, some of which are expressed in the male adult liver while the other subset seems to be active in several...

DEBLOCKING AND EMBEDDED CODING IN IMAGE COMMUNICATION SYSTEMS

GAO, FENG

This dissertation addresses two problems in image communication systems. The first problem is blocking effects reduction and the second problem is embedded coding. The problem of blocking effects...

Precambrian animal diversity: Putative phosphatized embryos from the Doushantuo Formation of China

Chen, Jun-Yuan, Oliveri, Paola, Li, Chia-Wei, Zhou, Gui-Qing, Gao, Feng, Hagadorn, James W., ...

Putative fossil embryos and larvae from the Precambrian phosphorite rocks of the Doushantuo Formation in Southwest China have been examined in thin section by bright field and polarized light...

Opposite effects of nitric oxide and nitroxyl on postischemic myocardial injury

Ma, Xin L., Gao, Feng, Liu, Gao-Lin, Lopez, Bernard L., Christopher, Theodore A., Fukuto, Jon M., ...

Recent experimental evidence suggests that reactive nitrogen oxide species can contribute significantly to postischemic myocardial injury. The aim of the present study was to evaluate the role of two...

Disruption of the telomerase catalytic subunit gene from Arabidopsis inactivates telomerase and leads to a slow loss of telomeric DNA

Fitzgerald, Matthew S., Riha, Karel, Gao, Feng, Ren, Shuxin, McKnight, Thomas D., Shippen, Dorothy E.

Telomerase is an essential enzyme that maintains telomeres on eukaryotic chromosomes. In mammals, telomerase is required for the lifelong proliferative capacity of normal regenerative and...

Minocycline prevents nigrostriatal dopaminergic neurodegeneration in the MPTP model of Parkinson's disease

Du, Yansheng, Ma, Zhizhong, Lin, Suizhen, Dodel, Richard C., Gao, Feng, Bales, Kelly R., ...

Parkinson's disease is a chronic neurodegenerative disorder characterized by the loss of dopamine neurons in the substantia nigra, decreased striatal dopamine levels, and consequent extrapyramidal...

Detection of Phylogenetically Diverse Human Immunodeficiency Virus Type 1 Groups M and O from Plasma by Using Highly Sensitive and Specific Generic Primers

Yang, Chunfu, Pieniazek, Danuta, Owen, Sherry M., Fridlund, Carol, Nkengasong, John, Mastro, Timothy D., ...

The high degree of genetic diversity within human immunodeficiency virus type 1 (HIV-1), which includes two major groups, M (major) and O (outlier), and various env subtypes within group M (subtypes...

Natural Infection of a Household Pet Red-Capped Mangabey (Cercocebus torquatus torquatus) with a New Simian Immunodeficiency Virus

Georges-Courbot, Marie Claude, Lu, Chong Yang, Makuwa, Maria, Telfer, Paul, Onanga, Richard, Dubreuil, Guy, ...

A seroprevalence survey was conducted for simian immunodeficiency virus (SIV) antibody in household pet monkeys in Gabon. Twenty-nine monkeys representing seven species were analyzed. By using human...

Genetically Divergent Strains of Human Immunodeficiency Virus Type 2 Use Multiple Coreceptors for Viral Entry

Owen, Sherry M., Ellenberger, Dennis, Rayfield, Mark, Wiktor, Stefan, Michel, Philippe, Grieco, Michael H., ...

Several members of the seven-transmembrane chemokine receptor family have been shown to serve, with CD4, as coreceptors for entry by human immunodeficiency virus type 1 (HIV-1). While coreceptor...

A Comprehensive Panel of Near-Full-Length Clones and Reference Sequences for Non-Subtype B Isolates of Human Immunodeficiency Virus Type 1

Gao, Feng, Robertson, David L., Carruthers, Catherine D., Morrison, Sandra G., Jian, Bixi, Chen, Yalu, ...

Non-subtype B viruses cause the vast majority of new human immunodeficiency virus type 1 (HIV-1) infections worldwide and are thus the major focus of international vaccine efforts. Although their...

An Isolate of Human Immunodeficiency Virus Type 1 Originally Classified as Subtype I Represents a Complex Mosaic Comprising Three Different Group M Subtypes (A, G, and I)

Gao, Feng, Robertson, David L., Carruthers, Catherine D., Li, Yingying, Bailes, Elizabeth, Kostrikis, Leondios G., ...

Full-length reference clones and sequences are currently available for eight human immunodeficiency virus type 1 (HIV-1) group M subtypes (A through H), but none have been reported for subtypes I and...

Functional Analysis of the Simian Immunodeficiency Virus Vpx Protein: Identification of Packaging Determinants and a Novel Nuclear Targeting Domain

Mahalingam, Sundarasamy, Van Tine, Brian, Santiago, Mario L., Gao, Feng, Shaw, George M., Hahn, Beatrice H.

The vpx gene products of human immunodeficiency virus type 2 (HIV-2) and of the closely related simian immunodeficiency viruses from sooty mangabeys (SIVsm) and macaques (SIVmac) comprise a...

Wild Mandrillus sphinx Are Carriers of Two Types of Lentivirus

Souquière, Sandrine, Bibollet-Ruche, Frédéric, Robertson, David L., Makuwa, Maria, Apetrei, Cristian, Onanga, Richard, ...

Mandrillus sphinx, a large primate living in Cameroon and Gabon and belonging to the Papionini tribe, was reported to be infected by a simian immunodeficiency virus (SIV) (SIVmndGB1) as early as...

Molecular Epidemiology of Human Immunodeficiency Virus Type 1 Transmission in a Heterosexual Cohort of Discordant Couples in Zambia

Trask, Stanley A., Derdeyn, Cynthia A., Fideli, Ulgen, Chen, Yalu, Meleth, Sreelatha, Kasolo, Francis, ...

Most human immunodeficiency virus type 1 (HIV-1) transmissions in sub-Saharan Africa are believed to occur between married adults who are discordant for their HIV-1 infection status; however, no...

Inhibition of IκB Kinase by a New Class of Retinoid-Related Anticancer Agents That Induce Apoptosis

Bayon, Yolanda, Ortiz, Maria A., Lopez-Hernandez, Francisco J., Gao, Feng, Karin, Michael, Pfahl, Magnus, ...

The transcription factor NF-κB is overexpressed or constitutively activated in many cancer cells, where it induces expression of antiapoptotic genes correlating with resistance to anticancer...

Unselected Mutations in the Human Immunodeficiency Virus Type 1 Genome Are Mostly Nonsynonymous and Often Deleterious

Gao, Feng, Chen, Yalu, Levy, David N., Conway, Joan A., Kepler, Thomas B., Hui, Huxiong

Mutation rates of human immunodeficiency virus type 1 (HIV-1) genomes have been estimated using purified reverse transcriptase or single-round infection system. Since small sequences were used as...

New Simian Immunodeficiency Virus Infecting De Brazza's Monkeys (Cercopithecus neglectus): Evidence for a Cercopithecus Monkey Virus Clade

Bibollet-Ruche, Frederic, Bailes, Elizabeth, Gao, Feng, Pourrut, Xavier, Barlow, Katrina L., Clewley, Jonathan P., ...

Nearly complete sequences of simian immunodeficiency viruses (SIVs) infecting 18 different nonhuman primate species in sub-Saharan Africa have now been reported; yet, our understanding of the...

Further Investigation of Simian Immunodeficiency Virus Vif Function in Human Cells

Gaddis, Nathan C., Sheehy, Ann M., Ahmad, K. Muneer, Swanson, Chad M., Bishop, Kate N., Beer, Brigitte E., ...

Primate lentivirus Vif proteins function by suppressing the antiviral activity of the cell-encoded apolipoprotein B mRNA-editing enzyme-catalytic polypeptide-like (APOBEC) proteins APOBEC3G and...

Antigenicity and Immunogenicity of a Synthetic Human Immunodeficiency Virus Type 1 Group M Consensus Envelope Glycoprotein

Gao, Feng, Weaver, Eric A., Lu, Zhongjing, Li, Yingying, Liao, Hua-Xin, Ma, Benjiang, ...

Genetic variation of human immunodeficiency virus (HIV-1) represents a major obstacle for AIDS vaccine development. To decrease the genetic distances between candidate immunogens and field virus...

Human Immunodeficiency Virus Type 1 env Clones from Acute and Early Subtype B Infections for Standardized Assessments of Vaccine-Elicited Neutralizing Antibodies

Li, Ming, Gao, Feng, Mascola, John R., Stamatatos, Leonidas, Polonis, Victoria R., Koutsoukos, Marguerite, ...

Induction of broadly cross-reactive neutralizing antibodies is a high priority for AIDS vaccine development but one that has proven difficult to be achieved. While most immunogens generate antibodies...

An Alternative and Effective HIV Vaccination Approach Based on Inhibition of Antigen Presentation Attenuators in Dendritic Cells

Song, Xiao-Tong, Evel-Kabler, Kevin, Rollins, Lisa, Aldrich, Melissa, Gao, Feng, Huang, Xue F, ...

Si-Yi Chen and colleagues describe a possible alternative strategy for HIV vaccination in mice involving suppressor of cytokine signaling (SOCS) in dendritic cells.

Trans -cyclopropanation of mycolic acids on trehalose dimycolate suppresses Mycobacterium tuberculosis –induced inflammation and virulence

Rao, Vivek, Gao, Feng, Chen, Bing, Jacobs, William R., Glickman, Michael S.

Recent studies have shown that fine structural modifications of Mycobacterium tuberculosis cell envelope lipids mediate host cell immune activation during infection. One such alteration in lipid...

Streptococcal Toxic Shock Syndrome Caused by Streptococcus suis Serotype 2

Tang, Jiaqi, Wang, Changjun, Feng, Youjun, Yang, Weizhong, Song, Huaidong, Chen, Zhihai, ...

Clinical description of a 2005 S. suis outbreak in China that affected over 200 individuals and initial characterization of the pathogenic isolates from affected pigs and humans.

GC-Profile: a web-based tool for visualizing and analyzing the variation of GC content in genomic sequences

Gao, Feng, Zhang, Chun-Ting

In order to understand the evolution, structure and function of genomes, it is important to know the general compositional features of DNA sequences. Based on the quadratic divergence, a new...

Cross-Subtype T-Cell Immune Responses Induced by a Human Immunodeficiency Virus Type 1 Group M Consensus Env Immunogen†

Weaver, Eric A., Lu, Zhongjing, Camacho, Zenaido T., Moukdar, Fatiha, Liao, Hua-Xin, Ma, Ben-Jiang, ...

The genetic diversity among globally circulating human immunodeficiency virus type 1 (HIV-1) strains is a serious challenge for HIV-1 vaccine design. We have generated a synthetic group M consensus...

The Rice Dwarf Virus P2 Protein Interacts with ent-Kaurene Oxidases in Vivo, Leading to Reduced Biosynthesis of Gibberellins and Rice Dwarf Symptoms1

Zhu, Shifeng, Gao, Feng, Cao, Xuesong, Chen, Mao, Ye, Gongyin, Wei, Chunhong, ...

The mechanisms of viral diseases are a major focus of biology. Despite intensive investigations, how a plant virus interacts with host factors to cause diseases remains poorly understood. The Rice...

Histidine 89 is an essential residue for Hsp70 in the phosphate transfer reaction

Lu, Yuanming, Hu, Qian, Yang, Cuixia, Gao, Feng

Autophosphorylation of Hsp70 is detected in the process of substrate refolding in the presence of adenosine triphosphate (ATP) in the reaction mixture. But to date, the role and mechanism of Hsp70...

Precambrian animal diversity: Putative phosphatized embryos from the Doushantuo Formation of China

Chen, Jun-Yuan, Oliveri, Paola, Li, Chia-Wei, Zhou, Gui-Qing, Gao, Feng, Hagadorn, James W., ...

Putative fossil embryos and larvae from the Precambrian phosphorite rocks of the Doushantuo Formation in Southwest China have been examined in thin section by bright field and polarized light...

Opposite effects of nitric oxide and nitroxyl on postischemic myocardial injury

Ma, Xin L., Gao, Feng, Liu, Gao-Lin, Lopez, Bernard L., Christopher, Theodore A., Fukuto, Jon M., ...

Recent experimental evidence suggests that reactive nitrogen oxide species can contribute significantly to postischemic myocardial injury. The aim of the present study was to evaluate the role of two...

Disruption of the telomerase catalytic subunit gene from Arabidopsis inactivates telomerase and leads to a slow loss of telomeric DNA

Fitzgerald, Matthew S., Riha, Karel, Gao, Feng, Ren, Shuxin, McKnight, Thomas D., Shippen, Dorothy E.

Telomerase is an essential enzyme that maintains telomeres on eukaryotic chromosomes. In mammals, telomerase is required for the lifelong proliferative capacity of normal regenerative and...

Minocycline prevents nigrostriatal dopaminergic neurodegeneration in the MPTP model of Parkinson's disease

Du, Yansheng, Ma, Zhizhong, Lin, Suizhen, Dodel, Richard C., Gao, Feng, Bales, Kelly R., ...

Parkinson's disease is a chronic neurodegenerative disorder characterized by the loss of dopamine neurons in the substantia nigra, decreased striatal dopamine levels, and consequent extrapyramidal...

Detection of Phylogenetically Diverse Human Immunodeficiency Virus Type 1 Groups M and O from Plasma by Using Highly Sensitive and Specific Generic Primers

Yang, Chunfu, Pieniazek, Danuta, Owen, Sherry M., Fridlund, Carol, Nkengasong, John, Mastro, Timothy D., ...

The high degree of genetic diversity within human immunodeficiency virus type 1 (HIV-1), which includes two major groups, M (major) and O (outlier), and various env subtypes within group M (subtypes...

Natural Infection of a Household Pet Red-Capped Mangabey (Cercocebus torquatus torquatus) with a New Simian Immunodeficiency Virus

Georges-Courbot, Marie Claude, Lu, Chong Yang, Makuwa, Maria, Telfer, Paul, Onanga, Richard, Dubreuil, Guy, ...

A seroprevalence survey was conducted for simian immunodeficiency virus (SIV) antibody in household pet monkeys in Gabon. Twenty-nine monkeys representing seven species were analyzed. By using human...

Genetically Divergent Strains of Human Immunodeficiency Virus Type 2 Use Multiple Coreceptors for Viral Entry

Owen, Sherry M., Ellenberger, Dennis, Rayfield, Mark, Wiktor, Stefan, Michel, Philippe, Grieco, Michael H., ...

Several members of the seven-transmembrane chemokine receptor family have been shown to serve, with CD4, as coreceptors for entry by human immunodeficiency virus type 1 (HIV-1). While coreceptor...

A Comprehensive Panel of Near-Full-Length Clones and Reference Sequences for Non-Subtype B Isolates of Human Immunodeficiency Virus Type 1

Gao, Feng, Robertson, David L., Carruthers, Catherine D., Morrison, Sandra G., Jian, Bixi, Chen, Yalu, ...

Non-subtype B viruses cause the vast majority of new human immunodeficiency virus type 1 (HIV-1) infections worldwide and are thus the major focus of international vaccine efforts. Although their...

An Isolate of Human Immunodeficiency Virus Type 1 Originally Classified as Subtype I Represents a Complex Mosaic Comprising Three Different Group M Subtypes (A, G, and I)

Gao, Feng, Robertson, David L., Carruthers, Catherine D., Li, Yingying, Bailes, Elizabeth, Kostrikis, Leondios G., ...

Full-length reference clones and sequences are currently available for eight human immunodeficiency virus type 1 (HIV-1) group M subtypes (A through H), but none have been reported for subtypes I and...

Functional Analysis of the Simian Immunodeficiency Virus Vpx Protein: Identification of Packaging Determinants and a Novel Nuclear Targeting Domain

Mahalingam, Sundarasamy, Van Tine, Brian, Santiago, Mario L., Gao, Feng, Shaw, George M., Hahn, Beatrice H.

The vpx gene products of human immunodeficiency virus type 2 (HIV-2) and of the closely related simian immunodeficiency viruses from sooty mangabeys (SIVsm) and macaques (SIVmac) comprise a...

Wild Mandrillus sphinx Are Carriers of Two Types of Lentivirus

Souquière, Sandrine, Bibollet-Ruche, Frédéric, Robertson, David L., Makuwa, Maria, Apetrei, Cristian, Onanga, Richard, ...

Mandrillus sphinx, a large primate living in Cameroon and Gabon and belonging to the Papionini tribe, was reported to be infected by a simian immunodeficiency virus (SIV) (SIVmndGB1) as early as...

Molecular Epidemiology of Human Immunodeficiency Virus Type 1 Transmission in a Heterosexual Cohort of Discordant Couples in Zambia

Trask, Stanley A., Derdeyn, Cynthia A., Fideli, Ulgen, Chen, Yalu, Meleth, Sreelatha, Kasolo, Francis, ...

Most human immunodeficiency virus type 1 (HIV-1) transmissions in sub-Saharan Africa are believed to occur between married adults who are discordant for their HIV-1 infection status; however, no...

Inhibition of IκB Kinase by a New Class of Retinoid-Related Anticancer Agents That Induce Apoptosis

Bayon, Yolanda, Ortiz, Maria A., Lopez-Hernandez, Francisco J., Gao, Feng, Karin, Michael, Pfahl, Magnus, ...

The transcription factor NF-κB is overexpressed or constitutively activated in many cancer cells, where it induces expression of antiapoptotic genes correlating with resistance to anticancer...

Unselected Mutations in the Human Immunodeficiency Virus Type 1 Genome Are Mostly Nonsynonymous and Often Deleterious

Gao, Feng, Chen, Yalu, Levy, David N., Conway, Joan A., Kepler, Thomas B., Hui, Huxiong

Mutation rates of human immunodeficiency virus type 1 (HIV-1) genomes have been estimated using purified reverse transcriptase or single-round infection system. Since small sequences were used as...

New Simian Immunodeficiency Virus Infecting De Brazza's Monkeys (Cercopithecus neglectus): Evidence for a Cercopithecus Monkey Virus Clade

Bibollet-Ruche, Frederic, Bailes, Elizabeth, Gao, Feng, Pourrut, Xavier, Barlow, Katrina L., Clewley, Jonathan P., ...

Nearly complete sequences of simian immunodeficiency viruses (SIVs) infecting 18 different nonhuman primate species in sub-Saharan Africa have now been reported; yet, our understanding of the...

Further Investigation of Simian Immunodeficiency Virus Vif Function in Human Cells

Gaddis, Nathan C., Sheehy, Ann M., Ahmad, K. Muneer, Swanson, Chad M., Bishop, Kate N., Beer, Brigitte E., ...

Primate lentivirus Vif proteins function by suppressing the antiviral activity of the cell-encoded apolipoprotein B mRNA-editing enzyme-catalytic polypeptide-like (APOBEC) proteins APOBEC3G and...

Antigenicity and Immunogenicity of a Synthetic Human Immunodeficiency Virus Type 1 Group M Consensus Envelope Glycoprotein

Gao, Feng, Weaver, Eric A., Lu, Zhongjing, Li, Yingying, Liao, Hua-Xin, Ma, Benjiang, ...

Genetic variation of human immunodeficiency virus (HIV-1) represents a major obstacle for AIDS vaccine development. To decrease the genetic distances between candidate immunogens and field virus...

Characterization of functional and phenotypic changes in anti-Gag vaccine-induced T cell responses and their role in protection after HIV-1 infection

Betts, Michael R., Exley, Barbara, Price, David A., Bansal, Anju, Camacho, Zenaido Tres, Teaberry, Vanessa, ...

Worldwide HIV-1 vaccine efforts are guided by the principle that HIV-specific T cell responses may provide protection from infection or delay overt disease. However, no clear correlates of T...

Human Immunodeficiency Virus Type 1 env Clones from Acute and Early Subtype B Infections for Standardized Assessments of Vaccine-Elicited Neutralizing Antibodies

Li, Ming, Gao, Feng, Mascola, John R., Stamatatos, Leonidas, Polonis, Victoria R., Koutsoukos, Marguerite, ...

Induction of broadly cross-reactive neutralizing antibodies is a high priority for AIDS vaccine development but one that has proven difficult to be achieved. While most immunogens generate antibodies...

The Rice Dwarf Virus P2 Protein Interacts with ent-Kaurene Oxidases in Vivo, Leading to Reduced Biosynthesis of Gibberellins and Rice Dwarf Symptoms1

Zhu, Shifeng, Gao, Feng, Cao, Xuesong, Chen, Mao, Ye, Gongyin, Wei, Chunhong, ...

The mechanisms of viral diseases are a major focus of biology. Despite intensive investigations, how a plant virus interacts with host factors to cause diseases remains poorly understood. The Rice...

An Alternative and Effective HIV Vaccination Approach Based on Inhibition of Antigen Presentation Attenuators in Dendritic Cells

Song, Xiao-Tong, Evel-Kabler, Kevin, Rollins, Lisa, Aldrich, Melissa, Gao, Feng, Huang, Xue F, ...

Si-Yi Chen and colleagues describe a possible alternative strategy for HIV vaccination in mice involving suppressor of cytokine signaling (SOCS) in dendritic cells.

Streptococcal Toxic Shock Syndrome Caused by Streptococcus suis Serotype 2

Tang, Jiaqi, Wang, Changjun, Feng, Youjun, Yang, Weizhong, Song, Huaidong, Chen, Zhihai, ...

Clinical description of a 2005 S. suis outbreak in China that affected over 200 individuals and initial characterization of the pathogenic isolates from affected pigs and humans.

Trans -cyclopropanation of mycolic acids on trehalose dimycolate suppresses Mycobacterium tuberculosis –induced inflammation and virulence

Rao, Vivek, Gao, Feng, Chen, Bing, Jacobs, William R., Glickman, Michael S.

Recent studies have shown that fine structural modifications of Mycobacterium tuberculosis cell envelope lipids mediate host cell immune activation during infection. One such alteration in lipid...

Histidine 89 is an essential residue for Hsp70 in the phosphate transfer reaction

Lu, Yuanming, Hu, Qian, Yang, Cuixia, Gao, Feng

Autophosphorylation of Hsp70 is detected in the process of substrate refolding in the presence of adenosine triphosphate (ATP) in the reaction mixture. But to date, the role and mechanism of Hsp70...

Cross-Subtype T-Cell Immune Responses Induced by a Human Immunodeficiency Virus Type 1 Group M Consensus Env Immunogen†

Weaver, Eric A., Lu, Zhongjing, Camacho, Zenaido T., Moukdar, Fatiha, Liao, Hua-Xin, Ma, Ben-Jiang, ...

The genetic diversity among globally circulating human immunodeficiency virus type 1 (HIV-1) strains is a serious challenge for HIV-1 vaccine design. We have generated a synthetic group M consensus...

GC-Profile: a web-based tool for visualizing and analyzing the variation of GC content in genomic sequences

Gao, Feng, Zhang, Chun-Ting

In order to understand the evolution, structure and function of genomes, it is important to know the general compositional features of DNA sequences. Based on the quadratic divergence, a new...

Genetic and Neutralization Properties of Subtype C Human Immunodeficiency Virus Type 1 Molecular env Clones from Acute and Early Heterosexually Acquired Infections in Southern Africa▿

Li, Ming, Salazar-Gonzalez, Jesus F., Derdeyn, Cynthia A., Morris, Lynn, Williamson, Carolyn, Robinson, James E., ...

A standard panel of subtype C human immunodeficiency virus type 1 (HIV-1) Env-pseudotyped viruses was created by cloning, sequencing, and characterizing functional gp160 genes from 18 acute and early...

Fibronectin-α4β1 Integrin Interactions Regulate Metalloproteinase-9 Expression in Steatotic Liver Ischemia and Reperfusion Injury

Moore, Carolina, Shen, Xiu-Da, Gao, Feng, Busuttil, Ronald W., Coito, Ana J.

Ischemia/reperfusion injury is a major cause of the highly dysfunctional rate observed in marginal steatotic orthotopic liver transplantation. In this study, we document that the interactions between...

Crystallization and preliminary X-ray structural studies of a high-affinity CD8αα co-receptor to pMHC

Cole, David K., Rizkallah, Pierre J., Sami, Malkit, Lissin, Nikolai M., Gao, Feng, Bell, John I., ...

A high-affinity mutant CD8 (haCD8) has been developed with the aim of developing a therapeutic immunosuppressor. In order to fully understand the nature of the haCD8 interaction, this protein was...

Mycobacterial Nonhomologous End Joining Mediates Mutagenic Repair of Chromosomal Double-Strand DNA Breaks▿

Stephanou, Nicolas C., Gao, Feng, Bongiorno, Paola, Ehrt, Sabine, Schnappinger, Dirk, Shuman, Stewart, ...

Bacterial nonhomologous end joining (NHEJ) is a recently described DNA repair pathway best characterized in mycobacteria. Bacterial NHEJ proteins LigD and Ku have been analyzed biochemically, and...

Preparation, Polymerization, and Characterization of Sugar-based Microemulsion Glasses

Gao, Feng

Sugar-based microemulsion glasses are novel non-aqueous self-assemblies, which extend microemulsions from their liquid state to their solid state. This new type of microemulsion is optically clear...

Anti-apoptotic effect of benidipine, a long-lasting vasodilating calcium antagonist, in ischaemic/reperfused myocardial cells

Gao, Feng, Gong, Bing, Christopher, Theodore A, Lopez, Bernard L, Karasawa, Akira, Ma, Xin L

Ischaemia/reperfusion causes intracellular calcium overloading in cardiac cells. Administration of calcium antagonists reduces myocardial infarct size. Recent in vitro studies have demonstrated that...

Antiapoptotic mechanisms of benidipine in the ischemic/reperfused heart

Liu, Hui-Rong, Gao, Feng, Tao, Ling, Yan, Wen-Li, Gao, Erhe, Christopher, Theodore A, ...

Considerable evidence indicates that calcium plays a critical role in apoptosis. We have previously shown that benidipine, a vasodilatory calcium channel blocker, attenuates postischemia myocardial...

In Vitro Selection and Characterization of Human Immunodeficiency Virus Type 2 with Decreased Susceptibility to Lopinavir▿

Masse, Sherie, Lu, Xiaozhi, Dekhtyar, Tatyana, Lu, Liangjun, Koev, Gennadiy, Gao, Feng, ...

Lopinavir (LPV)-ritonavir has demonstrated durable antiviral activity in human immunodeficiency virus type 1 (HIV-1)-infected antiretroviral-naïve and protease inhibitor (PI)-experienced patients....

X-ray crystallographic characterization of rhesus macaque MHC Mamu-A*02 complexed with an immunodominant SIV-Gag nonapeptide

Feng, Youjun, Qi, Jianxun, Zhang, Huimin, Wang, Jinzi, Liu, Jinhua, Jiang, Fan, ...

X-ray crystallographic characterization of rhesus macaque MHC Mamu-A*02 complexed with an immunodominant SIV-Gag nonapeptide.

Directed evolution of human T cell receptor CDR2 residues by phage display dramatically enhances affinity for cognate peptide-MHC without increasing apparent cross-reactivity

Dunn, Steven M., Rizkallah, Pierre J., Baston, Emma, Mahon, Tara, Cameron, Brian, Moysey, Ruth, ...

The mammalian α/β T cell receptor (TCR) repertoire plays a pivotal role in adaptive immunity by recognizing short, processed, peptide antigens bound in the context of a highly diverse family of...

Mechanically gated channel activity in cytoskeleton-deficient plasma membrane blebs and vesicles from Xenopus oocytes

Zhang, Yong, Gao, Feng, Popov, Vsevolod L, Wen, Julie W, Hamill, Owen P

A novel technique involving hypertonic stress causes membrane ‘blebbing’ of the Xenopus oocyte and the shedding of plasma membrane vesicles (PMVs).Confocal fluorescence microscopy,...

Reversal in multidrug resistance by magnetic nanoparticle of Fe3O4 loaded with adriamycin and tetrandrine in K562/A02 leukemic cells

Chen, Baoan, Sun, Qian, Wang, Xuemei, Gao, Feng, Dai, Yongyuan, Yin, Yan, ...

Drug resistance is a primary hindrance for efficiency of chemotherapy. To investigate whether Fe3O4-magnetic nanoparticles (Fe3O4-MNPs) loaded with adriamycin (ADM) and tetrandrine (Tet) would play a...

Transfer of a large gene regulatory apparatus to a new developmental address in echinoid evolution

Gao, Feng, Davidson, Eric H.

Of the five echinoderm classes, only the modern sea urchins (euechinoids) generate a precociously specified embryonic micromere lineage that ingresses before gastrulation and then secretes the...

Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection

Keele, Brandon F., Giorgi, Elena E., Salazar-Gonzalez, Jesus F., Decker, Julie M., Pham, Kimmy T., Salazar, Maria G., ...

The precise identification of the HIV-1 envelope glycoprotein (Env) responsible for productive clinical infection could be instrumental in elucidating the molecular basis of HIV-1 transmission and in...

ESTIMATION RISK IN GARCH VaR AND ES ESTIMATES

Gao, Feng, Song, Fengming

Value-at-risk (VaR) and expected shortfall (ES) are now both widely used risk measures. However, users have not paid much attention to the estimation risk issues, especially in the case of...

A centralized gene-based HIV-1 vaccine elicits broad cross-clade cellular immune responses in rhesus monkeys

Santra, Sampa, Korber, Bette T., Muldoon, Mark, Barouch, Dan H., Nabel, Gary J., Gao, Feng, ...

One of the major challenges that must be met in developing an HIV-1 vaccine is devising a strategy to generate cellular immunity with sufficient breadth to deal with the extraordinary genetic...

Synergistic effect of the combination of nanoparticulate Fe3O4 and Au with daunomycin on K562/A02 cells

Chen, Bao-An, Dai, Yong-Yuan, Wang, Xue-Mei, Zhang, Ren-Yun, Xu, Wen-Lin, Shen, Hui-Ling, ...

In this study, we have explored the possibility of the combination of the high reactivity of nano Fe3O4 or Au nanoparticles and daunomycin, one of the most important antitumor drugs in the treatment...

Unintended Consequences of Granting Small Firms Exemptions from Securities Regulation: Evidence from the Sarbanes-Oxley Act

FENG GAO, JOANNA SHUANG WU, JEROLD ZIMMERMAN

This paper provides evidence about the unintended consequences arising when small companies are exempted from costly regulations-these firms have incentives to stay small. Between 2003 and 2008, the...

Studies on the synthesis, characterization and properties of colossal magnetoresistive (CMR) materials

Gao, Feng

Metal oxides constitute an interesting class of materials with a wide range of properties. They exhibit a variety of phenomena such as ferromagnetism, ferroelectricity, and superconductivity. In the...

Origins of Replication in Sorangium cellulosum and Microcystis aeruginosa

Gao, Feng, Zhang, Chun-Ting

The genome of Sorangium cellulosum has recently been completely sequenced, and it is the largest bacterial genome sequenced so far. In their report, Schneiker et al. (in Complete genome sequence of...

Reversal of multidrug resistance by magnetic Fe3O4 nanoparticle copolymerizating daunorubicin and 5-bromotetrandrine in xenograft nude-mice

Chen, Baoan, Cheng, Jian, Wu, Yanan, Gao, Feng, Xu, Wenlin, Shen, Huilin, ...

In this paper we establish the xenograft leukemia model with stable multidrug resistance in nude mice and to investigate the reversal effect of 5-bromotetrandrine (5-BrTet) and magnetic nanoparticle...

Magnetic nanoparticle of Fe3O4 and 5-bromotetrandrin interact synergistically to induce apoptosis by daunorubicin in leukemia cells

Chen, Baoan, Cheng, Jian, Shen, Mingfang, Gao, Feng, Xu, Wenlin, Shen, Huilin, ...

Apoptosis is a common pathway that finally mediated the killing functions of anticancer drugs, which is an important cause of multidrug resistance (MDR). The aim of this study was to investigate the...

The reversal effect of magnetic Fe3O4 nanoparticles loaded with cisplatin on SKOV3/DDP ovarian carcinoma cells

Jiang, Zhi, Chen, Bao-An, Xia, Guo-Hua, Wu, Qiang, Zhang, Yu, Hong, Tie-Yan, ...

To explore whether the magnetic nanoparticles of Fe3O4 (MNPs-Fe3O4) loaded with cisplatin can reverse the diaminedichloro platinum (DDP) resistance to multidrug resistance of ovarian carcinoma cells...

Fluid-structure Interaction within a Layered Aortic Arch Model

Gao, Feng, Guo, Zhihong, Sakamoto, Makoto, Matsuzawa, Teruo

The response of wall stress to the elasticity of each layer in the aorta wall was investigated to understand the role of the different elastic properties of layers in the aortic dissection. The...

Hypermethylation and aberrant expression of secreted fizzled-related protein genes in pancreatic cancer

Bu, Xian-Min, Zhao, Cheng-Hai, Zhang, Ning, Gao, Feng, Lin, Shuai, Dai, Xian-Wei

AIM: To determine the methylation status and aberrant expression of some secreted frizzled-related protein (SFRP) genes in pancreatic cancer and explore their role in pancreatic carcinogenesis.

Adverse selection or advantageous selection? Risk and underwriting in China's health-insurance market

Gao, Feng, Powers, Michael R., Wang, Jun

Using data from China's individual health-insurance market, we study the problem of information asymmetry. Our preliminary results appear to contradict standard-model predictions, showing that...

Molecular cloning, expression, purification and crystallographic analysis of PRRSV 3CL protease

Tian, Xinsheng, Feng, Youjun, Zhao, Tiezhu, Peng, Hao, Yan, Jinghua, Qi, Jianxun, ...

Recombinant PRRSV 3CL protease was crystallized and the crystals diffracted to 2.1 Å resolution.

Rational or irrational expectations? Evidence from China's stock market

Feng Gao, Fengming Song, Jun Wang

Purpose – The paper aims to test the rational-expectations hypothesis using data from the Chinese stock market. Design/methodology/approach – The rational-expectations hypothesis plays a critical...

Studies on the synthesis, characterization and properties of colossal magnetoresistive (CMR) materials

Gao, Feng

Metal oxides constitute an interesting class of materials with a wide range of properties. They exhibit a variety of phenomena such as ferromagnetism, ferroelectricity, and superconductivity. In the...

Studies on the synthesis, characterization and properties of colossal magnetoresistive (CMR) materials

Gao, Feng

Metal oxides constitute an interesting class of materials with a wide range of properties. They exhibit a variety of phenomena such as ferromagnetism, ferroelectricity, and superconductivity. In the...

Comparative Proteomics Approach to Screening of Potential Diagnostic and Therapeutic Targets for Oral Squamous Cell Carcinoma*S⃞

Wang, Zhi, Jiang, Lu, Huang, Canhua, Li, Zhengyu, Chen, Lijuan, Gou, Lantu, ...

This work demonstrates that a comprehensive strategy of proteomics identification combined with further validation and detailed functional analysis should be adopted in the field of cancer biomarker...

Reversal of multidrug resistance by magnetic Fe3O4 nanoparticle copolymerizating daunorubicin and 5-bromotetrandrine in xenograft nude-mice

Chen, Baoan, Cheng, Jian, Wu, Yanan, Gao, Feng, Xu, Wenlin, Shen, Huilin, ...

In this paper we establish the xenograft leukemia model with stable multidrug resistance in nude mice and to investigate the reversal effect of 5-bromotetrandrine (5-BrTet) and magnetic nanoparticle...

Magnetic nanoparticle of Fe3O4 and 5-bromotetrandrin interact synergistically to induce apoptosis by daunorubicin in leukemia cells

Chen, Baoan, Cheng, Jian, Shen, Mingfang, Gao, Feng, Xu, Wenlin, Shen, Huilin, ...

Apoptosis is a common pathway that finally mediated the killing functions of anticancer drugs, which is an important cause of multidrug resistance (MDR). The aim of this study was to investigate the...

The reversal effect of magnetic Fe3O4 nanoparticles loaded with cisplatin on SKOV3/DDP ovarian carcinoma cells

Jiang, Zhi, Chen, Bao-An, Xia, Guo-Hua, Wu, Qiang, Zhang, Yu, Hong, Tie-Yan, ...

To explore whether the magnetic nanoparticles of Fe3O4 (MNPs-Fe3O4) loaded with cisplatin can reverse the diaminedichloro platinum (DDP) resistance to multidrug resistance of ovarian carcinoma cells...

In Vivo gp41 Antibodies Targeting the 2F5 Monoclonal Antibody Epitope Mediate Human Immunodeficiency Virus Type 1 Neutralization Breadth ▿

Shen, Xiaoying, Parks, Robert J., Montefiori, David C., Kirchherr, Jennifer L., Keele, Brandon F., Decker, Julie M., ...

The broadly neutralizing human monoclonal antibodies (MAbs) 2F5 and 4E10, both targeting the highly conserved human immunodeficiency virus type 1 (HIV-1) envelope membrane proximal external region...

Daunorubicin-loaded magnetic nanoparticles of Fe3O4 overcome multidrug resistance and induce apoptosis of K562-n/VCR cells in vivo

Chen, Bao-an, Lai, Bin-bin, Cheng, Jian, Xia, Guo-hua, Gao, Feng, Xu, Wen-lin, ...

Multidrug resistance (MDR) is a major obstacle to cancer chemotherapy. We evaluated the effect of daunorubicin (DNR)-loaded magnetic nanoparticles of Fe3O4 (MNPs-Fe3O4) on K562-n/VCR cells in vivo....

Effect of magnetic nanoparticles of Fe3O4 and 5-bromotetrandrine on reversal of multidrug resistance in K562/A02 leukemic cells

Cheng, Jian, Wu, Weiwei, Chen, Bao-an, Gao, Feng, Xu, Wenlin, Gao, Chong, ...

This study aims to evaluate the multidrug resistance (MDR) reversal activity by magnetic nanoparticles of Fe3O4 (MNPs-Fe3O4) and 5-bromotetrandrine (BrTet) MDR cell line K562/A02 solitarily or...

Synergistic effect of magnetic nanoparticles of Fe3O4 with gambogic acid on apoptosis of K562 leukemia cells

Chen, Baoan, Liang, Yiqiong, Wu, Weiwei, Cheng, Jian, Xia, Guohua, Gao, Feng, ...

Gambogic acid (GA) has a significant anticancer effect on a wide variety of solid tumors. Recently, many nanoparticles have been introduced as drug-delivery systems to enhance the efficiency of...

Studies on the synthesis, characterization and properties of colossal magnetoresistive (CMR) materials

Gao, Feng

Metal oxides constitute an interesting class of materials with a wide range of properties. They exhibit a variety of phenomena such as ferromagnetism, ferroelectricity, and superconductivity. In the...

Structural insight into the catalytic mechanism of gluconate 5-dehydrogenase from Streptococcus suis: Crystal structures of the substrate-free and quaternary complex enzymes

Zhang, Qiangmin, Peng, Hao, Gao, Feng, Liu, Yiwei, Cheng, Hao, Thompson, John, ...

Gluconate 5-dehydrogenase (Ga5DH) is an NADP(H)-dependent enzyme that catalyzes a reversible oxidoreduction reaction between d-gluconate and 5-keto-d-gluconate, thereby regulating the flux of this...

Crystallization and preliminary X-ray study of native and selenomethionyl β-1,4-mannanase AaManA from Alicyclobacillus acidocaldarius Tc-12-31

Zhang, Yueling, Gao, Feng, Xue, Yanfen, Zeng, Yan, Peng, Hao, Qi, Jianxun, ...

A. acidocaldarius Tc-12-31 β-1,4-mannanase was expressed in E. coli and purified. Crystallization and preliminarily X-ray crystallographic studies were performed for both the native mannanase and...

Expression, purification, crystallization and preliminary X-ray diffraction analysis of grass carp β2-microglobulin

Chen, Weihong, Chu, Fuliang, Peng, Hao, Zhang, Jianhua, Qi, Jianxun, Jiang, Fan, ...

Grass carp β2-microglobulin was expressed in E. coli, purified to homogeneity and crystallized using the hanging-drop vapour-diffusion method with PEG 2K as precipitant. The crystals obtained belong...

Crystal Structures of Streptococcus suis Mannonate Dehydratase (ManD) and Its Complex with Substrate: Genetic and Biochemical Evidence for a Catalytic Mechanism▿ †

Zhang, Qiangmin, Gao, Feng, Peng, Hao, Cheng, Hao, Liu, Yiwei, Tang, Jiaqi, ...

Mannonate dehydratase (ManD) is found only in certain bacterial species, where it participates in the dissimilation of glucuronate. ManD catalyzes the dehydration of d-mannonate to yield...