Scientific Commons: G. Lutfalla

A murine interferon (IFN) alpha/beta receptor was cloned from the IFN-sensitive L1210 cell line on the basis of its homology with the human receptor. A combination of methods that includes the...

Rearrangement and expression of rabbit immunoglobulin kappa light chain gene in transgenic mice.

Goodhardt, M, Cavelier, P, Akimenko, M A, Lutfalla, G, Babinet, C, Rougeon, F

To determine whether a foreign unrearranged immunoglobulin gene can be functionally rearranged and expressed in vivo, a rabbit b9 kappa light chain gene construct containing a single germ-line kappa...

HindIII RFLP at the human IFNAR locus

Vielh, E., Uzé, G., Lutfalla, G., Bandu, M.T., Mogensen, K.E.

Immunoglobulin kappa light chain gene promoter and enhancer are not responsible for B-cell restricted gene rearrangement.

Goodhardt, M, Babinet, C, Lutfalla, G, Kallenbach, S, Cavelier, P, Rougeon, F

We have produced transgenic mice which synthesize chimeric mouse-rabbit immunoglobulin (Ig) kappa light chains following in vivo recombination of an injected unrearranged kappa gene. The exogenous...

Mutant U5A cells are complemented by an interferon-alpha beta receptor subunit generated by alternative processing of a new member of a cytokine receptor gene cluster.

Lutfalla, G, Holland, S J, Cinato, E, Monneron, D, Reboul, J, Rogers, N C, ...

The cellular receptor for the alpha/beta interferons contains at least two components that interact with interferon. The ifnar1 component is well characterized and a putative ifnar2 cDNA has recently...

Behavior of a cloned murine interferon alpha/beta receptor expressed in homospecific or heterospecific background.

Uzé, G, Lutfalla, G, Bandu, M T, Proudhon, D, Mogensen, K E