G. P. Reynolds

Details der Publikationsliste

Zeitraum

1979 - 2007

Anzahl

18

Co-Autoren

Recombinant DNA studies on stored necropsy brain samples from patients with Huntington's chorea.

Upadhyaya, M, Reynolds, G P, Harper, P S

An analysis of deoxyribonucleic acid (DNA) in deep frozen brain samples taken from 100 patients with Huntington's chorea after death showed undegraded DNA in 44 cases. Of these, 16 were analysed with...

Tranylcypromine isomers and Parkinson's disease: new aspects of an old drug.

Reynolds, G P, Riederer, P, Sandler, M

The tranylcypromine stereoisomers have been investigated in a series of comparative trials in Parkinsons' disease and the results indicate that doses below 3 mg/day, of the (+)-isomer in particular,...

Neurochemical characteristics of early and late onset types of Alzheimer's disease.

Rossor, M N, Iversen, L L, Reynolds, G P, Mountjoy, C Q, Roth, M

Brains of 49 patients who had died with Alzheimer's disease and 54 controls were examined. The Alzheimer group exhibited noticeably reduced activity of the cholinergic marker enzyme choline...

5-Hydroxytryptamine (5-HT)4 receptors in post mortem human brain tissue: distribution, pharmacology and effects of neurodegenerative diseases.

Reynolds, G P, Mason, S L, Meldrum, A, De Keczer, S, Parnes, H, Eglen, R M, ...

1. The distribution, pharmacology and effects of neurodegenerative diseases on 5-HT4 receptors in human brain have been characterized in vitro. 2. The 5-HT4 receptor in post mortem human brain tissue...

Recommended minimum data to be collected in research studies on Alzheimer's disease. The MRC (UK) Alzheimer's Disease Workshop Steering Committee.

Wilcock, G K, Hope, R A, Brooks, D N, Lantos, P L, Oppenheimer, C, Reynolds, G P, ...

In order to be able to compare the results of research work carried out in different centres on Alzheimer's disease and dementia, it is necessary for there to be standardised assessment methods. The...

Alzheimer-like neurotransmitter deficits in adult Down's syndrome brain tissue.

Godridge, H, Reynolds, G P, Czudek, C, Calcutt, N A, Benton, M

Brain tissue taken at necropsy from five cases of Down's syndrome and six controls was analysed for changes in neurotransmitter markers. Concentrations of noradrenaline (NA), dopamine (DA) and its...