Low cytotoxicity of solid lipid nanoparticles in in vitro and ex vivo lung models (2009)
Nassimi, M., Schleh, C., Hussein, R., Lübbers, K., Pohlmann, G., ...
The aim of this study was to investigate the potential cytotoxicity of solid lipid nanoparticles (SLN) for human lung as a suitable drug delivery system (DDS). Therefore we used a human alveolar...
Koch, W., Pohlmann, G., Schwarz, K.
A system for delivering a reference number concentration (calibration source) is proposed as an alternative to using reference methods for calibrating instrumentation of ultrafine particle number...
Henjakovic, M., Martin, C., Hoymann, H.G., Sewald, K., Ressmeyer, A.R., Dassow, C., ...
A wide range of industrial chemicals can induce respiratory allergic reactions. Hence, there is an urgent need for methods identifying and characterizing the biological action of chemicals in the...
Inhalation juvenile rat studies can be performed as early as at day 4 post partum (2008)
Lewin, G., Fuhst, R., Berger-Preiß, E., Pohlmann, G., Buschmann, J.
In order to test the feasibility of nose-only inhalation exposure in neonatal rodents, an inhalation study with Verapamil hydrochloride (CAS No. 152-11-4) as a model compound was conducted in...
Henjakovic, M., Martin, C., Hoymann, H.G., Sewald, K., Ressmeyer, A.R., Dassow, C., ...
A wide range of industrial chemicals can induce respiratory allergic reactions. Hence, there is an urgent need for methods identifying and characterizing the biological action of chemicals in the...
24 months inhalation carcinogenicity study of bitumen fumes in Wistar (WU) rats (2007)
Fuhst, R., Creutzenberg, O., Ernst, H., Hansen, T., Pohlmann, G., Preiss, A., ...
PREISS, A., KOCH, W., KOCK, H., ELEND, M., RAABE, M., POHLMANN, G.
Objectives: Undertaking a chronic inhalation study on bitumen fume presents a challenge in terms of generating large amounts of representative fume. The objective of the study described in this and...
POHLMANN, G., PREISS, A., LEVSEN, K., RAABE, M., KOCH, W.
Objectives: The objective of the study described in this and an accompanying series of papers was to develop a laboratory generated exposure atmosphere to be used for chronic inhalation toxicity...
POHLMANN, G., PREISS, A., KOCH, W., KOCK, H., ELEND, M., RAABE, M.
Undertaking a chronic inhalation study on bitumen fume presents a challenge in terms of generating sufficient amounts of representative fume. The objective of the study described in this and in...
Pohlmann, G., Preiß, A., Levsen, K., Raabe, M., Koch, W.
OBJECTIVES: The objective of the study described in this and an accompanying series of papers was to develop a laboratory generated exposure atmosphere to be used for chronic inhalation toxicity...
Preiß, A., Koch, W., Kock, H., Raabe, M., Pohlmann, G.
OBJECTIVES: Undertaking a chronic inhalation study on bitumen fume presents a challenge in terms of generating large amounts of representative fume. The objective of the study described in this and...
Pohlmann, G., Preiss, A., Koch, W., Kock, H., Elend, M., Raabe, M.
Undertaking a chronic inhalation study on bitumen fume presents a challenge in terms of generating sufficient amounts of representative fume. The objective of the study described in this and in...
Preiss, A., Koch, W., Kock, H., Elend, M., Raabe, M., Pohlmann, G.
Objectives: Undertaking a chronic inhalation study on bitumen fume presents a challenge in terms of generating large amounts of representative fume. The objective of the study described in this and...
Pohlmann, G., Preiss, A., Levsen, K., Raabe, M., Koch, W.
Objectives: The objective of the study described in this and an accompanying series of papers was to develop a laboratory generated exposure atmosphere to be used for chronic inhalation toxicity...
Pohlmann, G., Preiss, A., Koch, W., Kock, H., Elend, M., Raabe, M.
Undertaking a chronic inhalation study on bitumen fume presents a challenge in terms of generating sufficient amounts of representative fume. The objective of the study described in this and in...
Preiss, A., Koch, W., Kock, H., Elend, M., Raabe, M., Pohlmann, G.
Objectives: Undertaking a chronic inhalation study on bitumen fume presents a challenge in terms of generating large amounts of representative fume. The objective of the study described in this and...
Pohlmann, G., Preiss, A., Levsen, K., Raabe, M., Koch, W.
Objectives: The objective of the study described in this and an accompanying series of papers was to develop a laboratory generated exposure atmosphere to be used for chronic inhalation toxicity...
Pohlmann, G., Preiss, A., Koch, W., Kock, H., Elend, M., Raabe, M.
Undertaking a chronic inhalation study on bitumen fume presents a challenge in terms of generating sufficient amounts of representative fume. The objective of the study described in this and in...
In this study, personal exposure samples were collected in order to validate bitumen fume condensate to be used for inhalation toxicity studies in rats. Three different laboratories analyzed personal...
Buschmann, J., Dasenbrock, C., Fuhst, R., Pohlmann, G., Bartsch, W., Creutzenberg, O., ...
Aim of the study was to investigate the potential toxic effects of di-n-butylamine (DBA), a known skin and eye irritating compound, on the respiratory tract after inhalation exposure for up to 91...
Trenn- und Klassifizierverfahren (2003)
DE 10162053 A UPAB: 20030820 NOVELTY - Particle carrier gas (e.g. air) passes through an ionization region (5) where the particles are given a unipolar charge. In the separation region (6a, b) they...
Receptor modeling of urban aerosol: Final results (2002)
Pohlmann, G., Koch, W., Theisen, M., Nießner, R.
An increasing number of reports on adverse health effects of fine particles calls for a more detailed characterization of these ambient particulates and the major contributing sources. To improve the...
Subchronic studies on man-made vitreous fibres. Toxicity results (2002)
Brown, R., Bellmann, B., Muhle, H., Ernst, H., Pohlmann, G., Sébastien, P.
Two 'alkaline earth silicate' wools - a calcium magnesium silicate and a calcium magnesium zirconium silicate - were examinated in a subchronic '90-day' rat inhalation assay. A preparation of a...
Subchronic studies on man-made vitreous fibres. Kinetics of inhaled particles (2002)
Bellmann, B., Muhle, H., Ernst, H., Pohlmann, G., Sébastien, P., Brown, R.
After subchronic exposure of rats to different fibre types [calcium magnesium silicate fibre, calcium magnesium zirconia silicate fibre, refractory ceramic fibre (RCF), non-fibrous material of that...
Vorrichtung zur Erzeugung von Aerosolen (2002)
Lingemann, R., Ott, W., Pohlmann, G., Windt, H.
DE 19823511 A UPAB: 20000118 NOVELTY - A screw conveyor and antistatic devices are used to control the rate of addition of the material to the air stream. DETAILED DESCRIPTION - The material is...
Subchronic Studies on Man-Made Vitreous Fibres: Toxicity Results (2002)
Brown, R. C., Bellmann, B., Muhle, H., Ernst, H., Pohlmann, G., Sebastien, P.
Two ‘alkaline earth silicate’ wools—a calcium magnesium silicate and a calcium magnesium zirconium silicate—were examined in a subchronic ‘90-day’ rat inhalation assay. A preparation of a...
Subchronic Studies on Man-Made Vitreous Fibres: Kinetics of Inhaled Particles (2002)
Bellmann, B., Muhle, H., Pohlmann, G., Sebastien, P., Brown, R. C.
After subchronic exposure of rats to different fibre types [calcium magnesium silicate fibre, calcium magnesium zirconia silicate fibre, refractory ceramic fibre (RCF), non-fibrous material of that...
Fuhst, R., Levsen, K., Koch, W., Muhle, H., Pohlmann, G., Preiß, A., ...
Pohlmann, G., Koch, W., Levsen, K., Preiß, A., Fuhst, R., Muhle, H., ...
Cross-fostering inhalation toxicity study with hcfc-123 in lactating sprague-dawley rats (2001)
Buschmann, J., Bartsch, W., Dasenbrock, C., Fuhst, R., Pohlmann, G., Preiß, A., ...
A study was performed in Sprague-Dawley rats (Crl:CD BR) to differentiate between effects of hydrofluorocarbon 123 (HCFC-123) on the lactating dam or on the fetus using fostering and cross-fostering...
Inhalation tolerance study for p-Aramid respirable fiber-shaped particulates (RFP) in rats (2000)
Bellmann, B., Creutzenberg, O., Dasenbrock, C., Ernst, H., Pohlmann, G., Muhle, H.
This study was designed to assess the lung clearance function in rats after subchronic exposure to p-aramid respirable fiber-shaped particulates (RFP). Male wistar rats were exposed 6 hrs/day, 5...
Inhalation Tolerance Study for p-Aramid Respirable Fiber-Shaped Particulates (RFP) in Rats (2000)
Bellmann, B., Creutzenberg, O., Dasenbrock, C., Ernst, H., Pohlmann, G., Muhle, H.
This study was designed to assess the lung clearance function in rats after subchronic exposure to p-aramid respirable fiber-shaped particulates (RFP). Male Wistar rats were exposed 6 hrs/day, 5...
90-Tage-Inhalationstoxizitätsprüfung von Di-n-butylamin an Wistar(WU)-Ratten (1999)
Buschmann, J., Dasenbrock, C., Pohlmann, G., Bartsch, W., Creutzenberg, O., Ernst, H., ...
Aim of the study was to investigate the potential toxic effects of di-n-butylamine (DBA) as an example of a skin and eye irritating compound after inhalation exposure over 91 days in rats [Crl: (WI)...
Micronucleus induction in V79 cells after direct exposure to whole cigarette smoke (1998)
Massey, E., Aufderheide, M., Koch, W., Lodding, H., Pohlmann, G., Windt, H., ...
Previous investigations on the effects of cigarette smoke on cultured cells have used mainly smoke condensate dissolved in culture medium. A system has been designed which allows direct exposure of...
Verfahren und Vorrichtung zur Bestimmung oder Einstellung des Ladungszustandes von Aerosolen (1997)
A process and assembly determines the charge state of an aerosol container. The novelty is that: (a) the process determines the concentration of neutral particles in relation to the total aerosol...
Partikel- und gasförmige Emissionen bei der Laseroberflächenbehandlung (1995)
Kirner, P., Pohlmann, G., Haferkamp, H., Püster, T.
Machine parts are laser treated by cladding, alloying or hardening, depending on the wear conditions. During these thermal laser treatments, gases and particles are emitted from the workpiece and the...
In the context of a field study into the ammonia and nitric acid phase partitioning the aerosol characteristics, i.e. size distributions, have been regarded besides concentrations of the chemical...
This contribution describes a new filter testing device for plane filter media using channel type diffusion batteries in conjunction with impaction stages. The basic ideas that lead to the specific...
Trautner, F., Reis, M., Repsold, U., Hietel, B., Schulz, F., Tschiersch, J., ...
In order to observe changes in size distribution and chemical composition of aerosol particles during the formation of orographic clouds size segregated aerosol samples were collected at two sites of...
Proc.of the European Aerosol Conf., Oxford, GB, September 7-11, 1992
Die Erfindung betrifft ein Verfahren zur Bestimmung der Groesse von Partikeln oder Blasen in einem Traegermedium mittels eines an sich bekannten Streulichtverfahrens mit mindestens zwei sich in einem...
The dry deposition of particle from the atmosphere is not well understood for reasons of surface variabilities and mutual interactions between surface and particle. However, even relatively simple...
The determination of the particle size distributions by diffusion batteries requires several different batteries or stages that are normally connected to a single particle counter step by step. In...
Das hier vorgestellte LDA-Verfahren erlaubt erstmals nicht nur die Erfassung der Partikelgeschwindigkeit in freier Strömung, sondern auch die simultane Bestimmung der Partikelgröße, und dies auch...
Dunkhorst, W., Holländer, W., Pohlmann, G.
For a field intercomparison of various widely used dust samplers, a reference instrument was needed. Based on a Wide Range Aerosol Classifier (WRAC), several improvements were introduced compared...
Size determination by laser Doppler anemometry (LDA) is not possible with conventional techniques for small particles. However, using non-Gaussian modes in a 2D-LDA, information on the particle...
A laser doppler method for the determination of particle deposition velocities (1989)
Pohlmann, G., Holländer, W., Morawietz, G.
The measuring technique is based on Laser Doppler Anemometry (LDA). When two laser beams intersect, an interference pattern is formed. Particles crossing this interference pattern emit a pulse of...
Very high volume aerosol sampling with a novel drum centrifuge (1987)
Wolter, H., Hollaender, W., Morawietz, G., Pohlmann, G.
A self ventilating aerosol sampler was developed with a flow rate of 1200 cubic meters/hr at 300 rpm. Sampling efficiencies ranged from 91% for 2.1 mym particles, 75% for 0.6 mym particles to 48% for...
A laser doppler method for the determination of particle fluxes - first results (1987)
Holländer, M., Hollaender, W., Pohlmann, G.
A laser doppler technique was used to determine deposition velocitiesof aerosol particles. The technique is applicable close to surfaces where other methods fail. (ITA)
Construction and performance of a modified Wide Range Aerosol Classifier (WRAC) (1986)
Dunkhorst, W., Holländer, W., Pohlmann, G.
In order to compare dust samplers of different design, a reference instrument is needed capable of measuring large particles at high wind speeds. Based on a design by Lundgren, the instrument was...
Design and performance of an aerosol reactor for photochemical studies (1984)
Behnke, W., Hollaender, W., Koch, W., Pohlmann, G.
A photoreactor was designed to optimize aerosol life times for photochemical studies. Aerosol decay rate was in the range 0.04-0.4 per hour depending on particle size. Good agreement with deposition...