Chambers, R. D., Parsons, M., Sandford, G., Thomas, E., Trmcic, J., Moilliet, J. S.
Reaction of a series of model hexyl derivatives of the form C6H13–X (X=Cl, Br, I, CO2Me, COMe, CHO) with both elemental fluorine and Selectfluor™ was studied in order to assess the impact of...
Baron, A., Sandford, G., Slater, R., Yufit, D. S., Howard, J. A. K., Vong, A.
Polyfunctional tetrahydropyrido[2,3-b]pyrazine scaffolds can be synthesized by sequential reaction of pentafluoropyridine with sodium phenylsulfinate and an appropriate diamine. The polyfunctionality...
Tetrahydropyrido 3,4-b pyrazine scaffolds from pentafluoropyridine. (2005)
Sandford, G., Slater, R., Yufit, D. S., Howard, J. A. K., Vong, A.
Representative polyfunctional tetrahydropyrido[3,4-b]pyrazine scaffolds have been synthesized very readily by a one-pot annelation reaction of pentafluoropyridine with appropriate diamines. The...
Chambers, R. D., Fox, M. A., Sandford, G.
1,3-Ketoesters and 1,3-diketones react with fluorine gas, using Durham multichannel modular microreactor technology, on a preparatively useful scale. High conversions and yields of monofluorinated...
Versatile gas/liquid microreactors for industry. (2005)
Chambers, R. D., Fox, M. A., Holling, D., Nakano, T., Okazoe, T., Sandford, G.
The design, fabrication, use and scale-out of versatile, multi-channel gas/liquid microreactors, which are suitable for both laboratory and industrial syntheses, are described. Direct fluorination...
Chambers, R. D., Fox, M. A., Holling, D., Nakano, T., Okazoe, T., Sandford, G.
Versatile and conveniently operated microreactor devices, suitable for long term chemical synthesis for both laboratory and industrial use, are described. Direct fluorination of ethyl acetoacetate by...
Polyhalogenated heterocyclic compounds : macrocycles from perfluoro-4-isopropylpyridine. (2003)
Chambers, R. D., Hoskin, P. R., Kenwright, A. R., Khalil, A., Richmond, P., Sandford, G., ...
Perfluoro-4-isopropylpyridine was used as a building block for the two-step synthesis of a variety of macrocyclic systems bearing pyridine sub-units which were characterised by X-ray crystallography....
Cooper, J. A., Olivares, C. M., Sandford, G.
Fluoroalkenes of general structure R-CF=CF-CF3 (2a, R = cyclopentyl and 2b, R = cyclohexyl), prepared in high yield in two steps from hexafluoropropene and the appropriate cycloalkane, react with...
Olah, G A, Laali, K K, Sandford, G
The reactivity of nitronium tetrafluoroborate in the nitration of deactivated di- and trifluoronitrobenzenes is enhanced in superacidic trifluoromethanesulfonic (triflic) acid compared with aprotic...
Clinical evaluation of the addition of gentamicin to commercially prepared mycological media.
Merz, W G, Sandford, G, Evans, G L
A simple procedure is presented whereby an antibiotic solution can be added to prepared agar media for conversion to a selective medium to isolate fungi. Gentamicin solution was deposited onto slants...
Olah, G A, Laali, K K, Sandford, G
The reactivity of nitronium tetrafluoroborate in the nitration of deactivated di- and trifluoronitrobenzenes is enhanced in superacidic trifluoromethanesulfonic (triflic) acid compared with aprotic...
Clinical evaluation of the addition of gentamicin to commercially prepared mycological media.
Merz, W G, Sandford, G, Evans, G L
A simple procedure is presented whereby an antibiotic solution can be added to prepared agar media for conversion to a selective medium to isolate fungi. Gentamicin solution was deposited onto slants...