Guang-Biao Zhou

Details der Publikationsliste

Zeitraum

2005 - 2005

Anzahl

12

Co-Autoren

Retinoic Acid and Arsenic for Treating Acute Promyelocytic Leukemia (2005)

Guang-Biao Zhou, Wei-Li Zhao, Zhen-Yi Wang, Sai-Juan Chen, Zhu Chen

What were the critical steps in the development of ATRA and arsenic as treatments for APL? Researchers in Shanghai tell the story and look to the future.

Retinoic Acid and Arsenic for Treating Acute Promyelocytic Leukemia

Zhou, Guang-Biao, Zhao, Wei-Li, Wang, Zhen-Yi, Chen, Sai-Juan, Chen, Zhu

What were the critical steps in the development of ATRA and arsenic as treatments for APL? Researchers in Shanghai tell the story and look to the future

AML1-ETO and C-KIT mutation/overexpression in t(8;21) leukemia: Implication in stepwise leukemogenesis and response to Gleevec

Wang, Yue-Ying, Zhou, Guang-Biao, Yin, Tong, Chen, Bing, Shi, Jing-Yi, Liang, Wen-Xue, ...

To explore the genetic abnormalities that cooperate with AML1-ETO (AE) fusion gene to cause acute myeloid leukemia (AML) with t(8;21), we screened a number of candidate genes and identified 11 types...

Retinoic Acid and Arsenic for Treating Acute Promyelocytic Leukemia

Zhou, Guang-Biao, Zhao, Wei-Li, Wang, Zhen-Yi, Chen, Sai-Juan, Chen, Zhu

What were the critical steps in the development of ATRA and arsenic as treatments for APL? Researchers in Shanghai tell the story and look to the future

AML1-ETO and C-KIT mutation/overexpression in t(8;21) leukemia: Implication in stepwise leukemogenesis and response to Gleevec

Wang, Yue-Ying, Zhou, Guang-Biao, Yin, Tong, Chen, Bing, Shi, Jing-Yi, Liang, Wen-Xue, ...

To explore the genetic abnormalities that cooperate with AML1-ETO (AE) fusion gene to cause acute myeloid leukemia (AML) with t(8;21), we screened a number of candidate genes and identified 11 types...

Oridonin, a diterpenoid extracted from medicinal herbs, targets AML1-ETO fusion protein and shows potent antitumor activity with low adverse effects on t(8;21) leukemia in vitro and in vivo

Zhou, Guang-Biao, Kang, Hui, Wang, Lan, Gao, Li, Liu, Ping, Xie, Jun, ...

Studies have documented the potential antitumor activities of oridonin, a compound extracted from medicinal herbs. However, whether oridonin can be used in the selected setting of hematology/oncology...

Treatment of acute promyelocytic leukaemia with all-trans retinoic acid and arsenic trioxide: a paradigm of synergistic molecular targeting therapy

Zhou, Guang-Biao, Zhang, Ji, Wang, Zhen-Yi, Chen, Sai-Juan, Chen, Zhu

To turn a disease from highly fatal to highly curable is extremely difficult, especially when the disease is a type of cancer. However, we can gain some insight into how this can be done by looking...

Analysis of phenotype–genotype connection: the story of dissecting disease pathogenesis in genomic era in China, and beyond

Shen, Yan, Xu, Qi, Han, Zeguang, Liu, Han, Zhou, Guang-Biao

DNA is the ultimate depository of biological complexity. Thus, in order to understand life and gain insights into disease pathogenesis, genetic information embedded in the sequence of DNA base pairs...

Dissection of mechanisms of Chinese medicinal formula Realgar-Indigo naturalis as an effective treatment for promyelocytic leukemia

Wang, Lan, Zhou, Guang-Biao, Liu, Ping, Song, Jun-Hong, Liang, Yang, Yan, Xiao-Jing, ...

To enhance therapeutic efficacy and reduce adverse effects, practitioners of traditional Chinese medicine (TCM) prescribe a combination of plant species/minerals, called formulae, based on clinical...

Long-term efficacy and safety of all-trans retinoic acid/arsenic trioxide-based therapy in newly diagnosed acute promyelocytic leukemia

Hu, Jiong, Liu, Yuan-Fang, Wu, Chuan-Feng, Xu, Fang, Shen, Zhi-Xiang, Zhu, Yong-Mei, ...

All-trans retinoic acid (ATRA)/arsenic trioxide (ATO) combination-based therapy has benefitted newly diagnosed acute promyelocytic leukemia (APL) in short-term studies, but the long-term efficacy and...