Höhling, A, Höltershinken, M, Hoffmann, P, Scholz, H
No abstract available.
The Wilms' tumor gene Wt1 is required for normal development of the retina. (2002)
Wagner, K.D., Wagner, N., Vidal, V.P.I., Schley, G., Wilhelm, D., Schedl, A., ...
The EMBO Journal, 21(2002) S.1398-1405
Scholz, H., Watzka, W., Vierhaus, P.
Ceramic mono- or multi-filament fibres based on PbMO3 (where M = metallic element or a combination of different metallic elements, which can occupy the 'B' position of the perowskite lattice) are new...
Formation of Al2O3 Fiber-Reinforced AlN/Al-Matrix Composites by Al(Mg)-Melt Nitridation. (1998)
Scholz, H., Guenther, R., Roedel, J., Greil, P.
Formation of composite materials by growth of the reaction product into a porous filler preform is controlled by the wetting behavior of the molten metal on the filler surface. the filler may be...
Synthesis of High Purity AlN by Nitridation of Li-Doped Al-Melt. (1998)
The isothermal nitridation of 2.3 wt% Li-doped Al-melt at 1273 K was investigated. Li promotes complete conversion of the Al to AlN and acts as a getter' reducing the oxygen impurities in the...
Thermal Shock Resistance of Ceramic Materials in Melt Immersion Tests. (1998)
Dienst, W., Scholz, H., Zimmermann, H.
Resistance to thermal crack formation is critical for ceramic materials considered for application in nuclear fusion reactors. A melt immersion test was developed to determine this threshold,...
Gefuellte Aluminiumoxidsol-Masse und Verwendungen hierfuer (1998)
Jahn, R., Glaubitt, W., Scholz, H.
Aluminium (Al) oxide sol filled with Al oxide powder and optionally other fillers is claimed. USE - The filled sol is used for making mouldings and as adhesive resistant to high temperature (all...
Neue piezoelektrische Verbundwerkstoffe für aktive und passive Anwendungen (1997)
Scholz, H., Watzka, W., Seifert, S., Glaubitt, W., Sporn, D., Schönecker, A., ...
Dielectric and ferroelectric properties of 1-3 composites containing thin PZT-fibers (1997)
Watzka, W., Seifert, S., Scholz, H., Sporn, D., Schönecker, A., Seffner, L.
Processing and properties of PZT-fibers for 1-3 composites (1995)
Scholz, H., Watzka, W., Sporn, D., Seffner, L., Schönecker, A.
Sol-gel derived PZT-fibers were prepared by the melt spinning method. The fiber diameter was adjusted in the range of 5 to 50 mu m. As-spun gel fibers were dried. pyrolyzed and sintered in controlled...
Preparation and ferroelectric behaviour of PZT-fibres (1995)
Watzka, W., Sporn, D., Franke, K., Scholz, H.
Lead zirconate titanate fibres of the copmosition Pb(Zr0.53Ti0.47)O3 have been developed via the sol-gel route using a melt-spinning process. The spun PZT gel-fibres were treated thermally by a...
Densification and properties of sol-gel-derived PZT fibers for 1-3 composites (1995)
Scholz, H., Sporn, D., Ullrich, A., Schönecker, A., Martin, W.
The microstructural evolution of sol-gel derived PZT- fibers is strongly dependent on the atmosphere and the T/t-schedule of drying, pyrolysis and sintering. The PbO-partial pressure during sintering...
Sol-Gel-Verfahren zur Herstellung von PZT-Fasermaterialien (1994)
Sporn, D., Glaubitt, W., Jahn, R., Elbe, F., Ullrich, A., Scholz, H.
Aus kommerziell verfügbaren Metallalkoholaten bzw. -carboxylaten wurde durch gezielte chemische Modifizierung ein neuartiges Verfahren zur Herstellung von PZT-Endlosfasern entwickelt. Danach...
Eschenhagen, T., Mende, U., Schmitz, W., Scholz, H., Sempell, R., ...
Increased plasma concentrations of catecholamines are assumed to be responsible for the decreased sensitivity to catccholamines of the failing heart. We investigated in rat heart the influence of a...
The role of alpharadrenergic and muscarinic receptors in cardiac function (1991)
Schmitz, W., Eschenhagen, T., Mende, U., Moller, F. U., Scholz, H.
The positive inotropic effect of an alpha1-adrcnoccptor agonist, such as phenylephrine, is accompanied by an increase in the presumed second messenger, inositol 1,4,5-trisphosphate (1,4,5-IP3) and...
POSSIBLE INVOLVEMENT OF INOSITOL-LIPID METABOLISM IN MALIGNANT HYPERTHERMIA (1991)
SCHOLZ, J., ROEWER, N., RUM, U., SCHMITZ, W., SCHOLZ, H.
α-Adrenoceptor stimulation may induce malignant hyperthermia (MH) in vivo. Consequently, we have investigated the effects of the α-adrenoceptor agonist phenylephrine and, for comparison, the...
Thermal shock resistance of ceramic materials in melt immersion tests. (1990)
Dienst, W., Scholz, H., Zimmermann, H.
Journal of the European Ceramic Society, 5(1989) S.365-70
Pharmacological actions of various inotropic agents (1983)
The aim of this paper is to describe various positive inotropic drugs (except the cardiac glycosides) and to attempt a classification according to their mechanism of action. The most important drugs...
Dissertation, Univ.Karlsruhe 1973
KFK-1680 (Oktober 72)
KFK-1193 (Mai 70)
Born, H.J., Krawczynski, S., Ochsenfeld, W., Scholz, H.
Chem. Ing. Techn., 34 (1962) H. 8, S. 537-41
Pneumatische Foerderung und Dosierung radioaktiver Loesungen im Labormassstab (1961)
Kerntechnik, 3 (1961) Heft 6, S. 261-263
Using isolated rat kidneys perfused at controlled pressure, we examined a potential role of endothelium-derived relaxing factor (EDRF) in the pressure control of renin secretion. We found that...
Erythropoietin in polycystic kidneys.
Eckardt, K U, Möllmann, M, Neumann, R, Brunkhorst, R, Burger, H U, Lonnemann, G, ...
Erythropoietin (EPO) formation in kidneys of 18 patients with autosomal dominant polycystic kidney disease (ADPKD) was investigated. In 12 patients on hemodialysis and in 6 patients with preterminal...
Interrelation between baroreceptor and macula densa mechanisms in the control of renin secretion.
1. It was the aim of this study to examine the interrelation between 'baroreceptor' function and the macula densa signal in the control of renin secretion from the kidneys. To this end we...
Differential response of renin secretion to vasoconstrictors in the isolated perfused rat kidney.
Scholz, H, Kaissling, B, Inagami, T, Kurtz, A
1. We have examined whether an increase of renal vascular resistance is generally accompanied by an inhibition of renin secretion. The effects of vasoconstriction produced by angiotensin II (Ang II),...
1. A voltage-clamp method combining a single surcose gap and two intracellular micro-electrodes was used to measure membrane currents in ventricullar myocardial fibres. 2. The adequacy of the...
The regulation of the calcium conductance of cardiac muscle by adrenaline.
1. The effect of adrenaline on the Ca-dependent slow inward current, Is, of mammalian cardiac muscle has been investigated by the voltage-clamp method. The mechanism of the increase in the...
The effect of the internal sodium concentration on calcium fluxes in isolated guinea-pig auricles
Glitsch, H. G., Reuter, H., Scholz, H.
1. Calcium efflux from guinea-pig auricles followed saturation kinetics when [Ca]o and [Na]o were changed while the ratio [Ca]o/[Na]o2 was kept constant. The Michaelis constant, KmCa+Na = 40 mM,...
Genetic Dissection of Pointed, a Drosophila Gene Encoding Two Ets-Related Proteins
Scholz, H., Deatrick, J., Klaes, A., Klambt, C.
The Drosophila gene pointed (pnt) is required for the differentiation of a number of tissues during embryogenesis, including the ventral ectoderm, the nervous system, the tracheal system and certain...
Using isolated rat kidneys perfused at controlled pressure, we examined a potential role of endothelium-derived relaxing factor (EDRF) in the pressure control of renin secretion. We found that...
Erythropoietin in polycystic kidneys.
Eckardt, K U, Möllmann, M, Neumann, R, Brunkhorst, R, Burger, H U, Lonnemann, G, ...
Erythropoietin (EPO) formation in kidneys of 18 patients with autosomal dominant polycystic kidney disease (ADPKD) was investigated. In 12 patients on hemodialysis and in 6 patients with preterminal...
Interrelation between baroreceptor and macula densa mechanisms in the control of renin secretion.
1. It was the aim of this study to examine the interrelation between 'baroreceptor' function and the macula densa signal in the control of renin secretion from the kidneys. To this end we...
Differential response of renin secretion to vasoconstrictors in the isolated perfused rat kidney.
Scholz, H, Kaissling, B, Inagami, T, Kurtz, A
1. We have examined whether an increase of renal vascular resistance is generally accompanied by an inhibition of renin secretion. The effects of vasoconstriction produced by angiotensin II (Ang II),...
Genetic Dissection of Pointed, a Drosophila Gene Encoding Two Ets-Related Proteins
Scholz, H., Deatrick, J., Klaes, A., Klambt, C.
The Drosophila gene pointed (pnt) is required for the differentiation of a number of tissues during embryogenesis, including the ventral ectoderm, the nervous system, the tracheal system and certain...
1. A voltage-clamp method combining a single surcose gap and two intracellular micro-electrodes was used to measure membrane currents in ventricullar myocardial fibres. 2. The adequacy of the...
The regulation of the calcium conductance of cardiac muscle by adrenaline.
1. The effect of adrenaline on the Ca-dependent slow inward current, Is, of mammalian cardiac muscle has been investigated by the voltage-clamp method. The mechanism of the increase in the...
The effect of the internal sodium concentration on calcium fluxes in isolated guinea-pig auricles
Glitsch, H. G., Reuter, H., Scholz, H.
1. Calcium efflux from guinea-pig auricles followed saturation kinetics when [Ca]o and [Na]o were changed while the ratio [Ca]o/[Na]o2 was kept constant. The Michaelis constant, KmCa+Na = 40 mM,...
1. The myocardial uptake and the positive inotropic effect of theophylline (100 mug/ml; 0.56 mM) were studied in isolated electrically driven guinea-pig hearts perfused by the Langendorff technique...
Relationship between theophylline uptake and inotropic effect in the guinea-pig heart
1 The time course of the positive inotropic effect of theophylline was compared with the time course of the uptake and release of [3H]-theophylline in guinea-pig isolated, electrically driven hearts...
Böhm, M., Brückner, R., Neumann, J., Nose, M., Schmitz, W., Scholz, H.
1 Adenosine and the adenosine receptor agonist (-)-N6-phenylisopropyladenosine (PIA) produced a small positive and negative inotropic effect, respectively, in isolated electrically driven papillary...
Steinkraus, V., Nose, M., Scholz, H., Thormählen, K.
1. It has been suggested that impaired beta-adrenoceptor stimulation is a condition under which the functional role of cardiac alpha 1-adrenoceptors is enhanced. We therefore investigated the extent...
Cardiac alpha 1-adrenoceptor densities in different mammalian species.
Steinfath, M., Chen, Y. Y., Lavický, J., Magnussen, O., Nose, M., Rosswag, S., ...
1. alpha 1-Adrenoceptor densities were studied in cardiac membrane preparations from several mammalian species including human failing hearts under identical experiment conditions; the alpha...
Phosphodiesterase inhibition in ventricular cardiomyocytes from guinea-pig hearts.
Bethke, T., Meyer, W., Schmitz, W., Scholz, H., Stein, B., Thomas, K., ...
1. The present study compared the cyclic nucleotide phosphodiesterase (PDE) activities in cardiomyocytes and ventricular cardiac tissue from guinea-pigs. The aim of the study was to determine whether...
Kohl, C., Linck, B., Schmitz, W., Scholz, H., Scholz, J., Tóth, M.
1. The effects of carbachol and the A1-adenosine receptor agonist (-)-N6-phenylisopropyladenosine (PIA) on force of contraction and inositol lipid metabolism were studied in electrically driven left...
The mechanism of the cyclic AMP-independent positive inotropic effect of cardiac alpha-adrenoceptor stimulation was studied by analyzing the effects of phenylephrine on force of contraction,...
Interaction between sotalol and an antacid preparation
Läer, S., Neumann, J., Scholz, H.
Aims The aim of the study was to investigate the pharmacokinetic interaction between sotalol and antacids, and its pharmacodynamic relevance.