Becker, L., Wegerer, J.von, Schenkel, J., Zeilhofer, H.U., Swandulla, D., Weiher, H.
The Journal of Neuroscience, 22(2002) S.2505-12
Schenkel, J., Gaissert, H., Protopapa, E.E., Weiher, H., Gissmann, L., Alonso, A.
The Journal of Investigative Dermatology, 112(1999) S.893-98
Reuter, A., Nestl, A., Zwacka, R.M., Tuckermann, J., Waldherr, R., Wagner, E.M., ...
Molecular Biology of the Cell, 9(1998)S.1675-1682
Mausmodelle für menschliche Krankheiten: Eine 'spastische' Maus. (1997)
Nachrichten - Forschungszentrum Karlsruhe, 29(1997) S.269-73
Jäger, R., Herzer, U., Schenkel, J., Weiher, H.
Oncogene, 15(1997) S.1787-95
The human ubiquitin C promoter directs high ubiquitous expression of transgenes in mice (1996)
Schorpp, M, Jager, R, Schellander, K, Schenkel, J, Wagner, EF, Weiher, H, ...
67.Jahresversammlung der Deutschen Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie, Aachen, 18.-22.Mai 1996
Hartenstein, B., Schenkel, J., Kuhse, J., Besenbeck, B., Kling, C., Becker, C.M., ...
EMBO Journal, 15(1996) S.1275-82
Reuter, A., Zwacka, R.M., Weiher, H.
33rd Workshop on Inner Ear Biology, Utrecht, NL, August 31 - September 3, 1996
The effect of Mpv17 glomerulosclerosis gene on the inner ear. (1996)
33rd Workshop on Inner Ear Biology, Utrecht, NL, August 31 - September 3, 1996
Studies on the regulation of HPV11 gene expression in transgenic mice. (1996)
Gaissert, H., Gissmann, L., Weiher, H., Alonso, A., Schenkel, J.
6th felasa Symp., Basel, CH, June 19-21, 1996
The human ubiquitin C promoter directs high ubiquitous expression of transgenes in mice. (1996)
Schorpp, M., Jäger, R., Schellander, K., Schenkel, J., Wagner, E.F., Weiher, H., ...
Nucleic Acids Research, 24(1996) S.1787-88
Control of human papillomavirus type 11 (HPV11) transcription in transgenic mice. (1996)
Gaissert, H., Weiher, H., Gissmann, L., Alonso, A., Schenkel, J.
Cold Spring Harbor Conf.on Mouse Molecular Genetics, Cold Spring Harbor, N.Y., August 28 - September 1, 1996
Mpv17-glomerulosclerosis gene is essential for the inner ear function. (1996)
Meyer Zum Gottesberge, A.M., Nolting, K., Reuter, A., Weiher, H.
European Workgroup on Genetics of Hearing Impairment, Milano, I, October 11-13, 1996
Transgenic mouse models of neurological disorders due to glycine receptor defects. (1995)
Hartenstein, B., Schenkel, J., Kuhse, J., Betz, H., Weiher, H.
The Meeting of European Neuroscience, Amsterdam, NL, September 3-7, 1995
An human Mpv17-transgene rescues the glomerulosclerosis phenotype of Mpv17 defective mice. (1995)
Schenkel, J., Zwacka, R.M., Rutenberg, C., Reuter, A., Weiher, H.
33.Wissenschaftliche Tagung der Gesellschaft für Versuchstierkunde GV-SOLAS, Aachen, 11.-14.September 1995
Gack, S., Vallon, R., Schmidt, J., Grigoriadis, A., Tuckermann, J., Schenkel, J., ...
Cell Growth and Differentiation, 6(1995) S.759-67
Schenkel, J., Zwacka, R.M., Rutenberg, C., Reuter, A., Waldherr, R., Weiher, H.
Kidney International, 48(1995) S.80-84
Reuter, A., Zwacka, R.M., Karasawa, M., Weiher, H.
FEBS Advanced Course 94-18, Belgian Soc.for Cell Biology and Biochemistry, Gent, B, May 18-21, 1994
Brusa, R., Zimmermann, F., Weiher, H., Karasawa, M., Seeburg, P.H., Sprengel, R.
Cold Spring Harbor Conf.on Mouse Molecular Genetics, Cold Spring Harbor, N.Y., August 30 - September 4, 1994
Zwacka, R.M., Reuter, A., Pfaff, E., Moll, J., Gorgas, K., Karasawa, M., ...
The EMBO Journal, 13(1994) S.5129-34
The transgenic mouse strain Mpv17 as a model for peroxisomal disease. (1993)
Zwacka, R., Karasawa, M., Weiher, H.
SFBBM/SBCF-FEBS Satellite Internat.Meeting: Cellular Aspects Related to Peroxisomes, Dijon, F, April 28-29, 1993
Mpv17, a transgenic mouse model of peroxisomal disease. (1993)
5.Jahrestagung der Gesellschaft fuer Humangenetik, Wuerzburg, 17.-20.Maerz 1993
The murine glomerulosclerosis gene Mpv17 gene codes for a peroxisomal protein. (1993)
Zwacka, R., Karasawa, M., Reuter, A., Weiher, H.
EMBL Conf.Mouse Molecular Genetics, Heidelberg, August 19-22, 1993
Functional studies on the role of the CD44 variant meta-1 in the metastasis. (1993)
Jaeger, R., Schenkel, J., Herrlich, P., Weiher, H.
EMBL Conf.Mouse Molecular Genetics, Heidelberg, August 19-22, 1993
The human homolog of the glomerulosclerosis gene Mpv17: structure and genomic organization. (1993)
Karasawa, M., Zwacka, R., Reuter, A., Fink, T., Hsieh, C.L., Lichter, P., ...
Human Molecular Genetics, 2(1993) S.1829-34
Overexpression and inactivation of the #a§1 subunit gene of the glycine receptor. (1992)
Schenkel, J., Wolfframm, Ch., Schorpp, M., Betz, H., Weiher, H.
Cold Spring Harbor Laboratory, Mouse Molecular Genetics Meeting, New York, N.Y., August 26-30, 1992
Glomerulosclerose chez les souris transgeniques: le gene Mpv17 et son homologue chez l'homme. (1992)
Funck-Brentano, J.L. [Hrsg.]
Habilitationsschrift, Unitersitaet Karlsruhe 1992
Gray, D.A., Gupta, K., Weiher, H., Jaenisch, R.
EMBL-Conf. on Mouse Molecular Genetics, Heidelberg, August 21-25, 1991
Studies on the metastatic potential of meta-1, a splice variant of CD44 in transgenic mice. (1991)
Hofmann, M., Beermann, F., Herrlich, P., Weiher, H.
EMBL-Conf. on Mouse Molecular Genetics, Heidelberg, August 21-25, 1991
Schorpp, M., Wolfframm, Ch., Weiher, H., Angel, P.
EMBL-Conf. on Mouse Molecular Genetics, Heidelberg, August 21-25, 1991
Weiher, H., Noda, T., Grey, D.A., Sharpe, A., Jaenisch, R.
Cell, 62(1990) S.425-34
The function of the MPV17 gene product in mouse and man. (1990)
Weiher, H., Pfaff, E., Noda, T., Jaenisch, R., Gray, D., Sharpe, A.
Cold Spring Harbor Laboratory Meeting 'Mouse Molecular Genetics', Cold Spring Harbor, August 29 - September 9, 1990
An enhancer sequence from bovine papilloma virus DNA consists of two essential regions (1984)
A comprehensive structural analysis of an enhancer sequence from bovine papilloma virus DNA is presented based on the construction and functional analysis of 20 mutant derivatives. The results,...
The human ubiquitin C promoter directs high ubiquitous expression of transgenes in mice.
Schorpp, M, Jäger, R, Schellander, K, Schenkel, J, Wagner, E F, Weiher, H, ...
Proviral inactivation of the Npat gene of Mpv 20 mice results in early embryonic arrest.
Di Fruscio, M, Weiher, H, Vanderhyden, B C, Imai, T, Shiomi, T, Hori, T A, ...
The Mpv 20 transgenic mouse strain was created by infection of embryos with a defective retrovirus. When Mpv 20 heterozygous animals were crossed, no homozygous neonatal mice or midgestation embryos...
Rohdewohld, H, Weiher, H, Reik, W, Jaenisch, R, Breindl, M
The chromatin conformation of mouse genome regions containing Moloney murine leukemia proviral intergration sites in two Mov mouse strains and randomly selected integration sites in virus-infected...
Two distinct sequence elements mediate retroviral gene expression in embryonal carcinoma cells.
Weiher, H, Barklis, E, Ostertag, W, Jaenisch, R
Moloney murine leukemia virus (M-MuLV) and M-MuLV-derived retroviral vectors are not expressed in early mouse embryos or in embryonal carcinoma cells. M-MuLV-derived mutants or M-MuLV-related...
An enhancer sequence from bovine papilloma virus DNA consists of two essential regions.
A comprehensive structural analysis of an enhancer sequence from bovine papilloma virus DNA is presented based on the construction and functional analysis of 20 mutant derivatives. The results,...
Segment-specific mutagenesis: extensive mutagenesis of a lac promoter/operator element.
A method for highly efficient segment-specific mutagenesis is described. The method uses as target for sodium bisulfite mutagenesis the DNA single strands of a DNA restriction fragment that had been...
Lusky, M, Berg, L, Weiher, H, Botchan, M
Bovine papilloma virus (BPV) contains a cis-acting DNA element which can enhance transcription of distal promoters. Utilizing both direct and indirect transient transfection assays, we showed that a...
The glomerulosclerosis gene Mpv17 encodes a peroxisomal protein producing reactive oxygen species.
Zwacka, R M, Reuter, A, Pfaff, E, Moll, J, Gorgas, K, Karasawa, M, ...
The mutant mouse strain Mpv17 carries a retroviral insert in its genome which inactivates the Mpv17 gene. At a young age these mice develop glomerulosclerosis and nephrotic syndrome which resembles...
Reik, W, Weiher, H, Jaenisch, R
A bacterial suppressor tRNA gene was introduced into the long terminal repeat of the Moloney murine leukemia virus (Mo-MuLV) proviral genome to construct a retrovirus that allows easy cloning of the...
Hartenstein, B, Schenkel, J, Kuhse, J, Besenbeck, B, Kling, C, Becker, C M, ...
Mutations in inhibitory glycine receptor (GlyR) subunit genes are associated with neuromotor diseases in man and mouse. To use the potential of the mouse mutants as animal models of human disease, we...
The human ubiquitin C promoter directs high ubiquitous expression of transgenes in mice.
Schorpp, M, Jäger, R, Schellander, K, Schenkel, J, Wagner, E F, Weiher, H, ...
Proviral inactivation of the Npat gene of Mpv 20 mice results in early embryonic arrest.
Di Fruscio, M, Weiher, H, Vanderhyden, B C, Imai, T, Shiomi, T, Hori, T A, ...
The Mpv 20 transgenic mouse strain was created by infection of embryos with a defective retrovirus. When Mpv 20 heterozygous animals were crossed, no homozygous neonatal mice or midgestation embryos...
Rohdewohld, H, Weiher, H, Reik, W, Jaenisch, R, Breindl, M
The chromatin conformation of mouse genome regions containing Moloney murine leukemia proviral intergration sites in two Mov mouse strains and randomly selected integration sites in virus-infected...
Two distinct sequence elements mediate retroviral gene expression in embryonal carcinoma cells.
Weiher, H, Barklis, E, Ostertag, W, Jaenisch, R
Moloney murine leukemia virus (M-MuLV) and M-MuLV-derived retroviral vectors are not expressed in early mouse embryos or in embryonal carcinoma cells. M-MuLV-derived mutants or M-MuLV-related...
An enhancer sequence from bovine papilloma virus DNA consists of two essential regions.
A comprehensive structural analysis of an enhancer sequence from bovine papilloma virus DNA is presented based on the construction and functional analysis of 20 mutant derivatives. The results,...
Segment-specific mutagenesis: extensive mutagenesis of a lac promoter/operator element.
A method for highly efficient segment-specific mutagenesis is described. The method uses as target for sodium bisulfite mutagenesis the DNA single strands of a DNA restriction fragment that had been...
Lusky, M, Berg, L, Weiher, H, Botchan, M
Bovine papilloma virus (BPV) contains a cis-acting DNA element which can enhance transcription of distal promoters. Utilizing both direct and indirect transient transfection assays, we showed that a...
The glomerulosclerosis gene Mpv17 encodes a peroxisomal protein producing reactive oxygen species.
Zwacka, R M, Reuter, A, Pfaff, E, Moll, J, Gorgas, K, Karasawa, M, ...
The mutant mouse strain Mpv17 carries a retroviral insert in its genome which inactivates the Mpv17 gene. At a young age these mice develop glomerulosclerosis and nephrotic syndrome which resembles...
Reik, W, Weiher, H, Jaenisch, R
A bacterial suppressor tRNA gene was introduced into the long terminal repeat of the Moloney murine leukemia virus (Mo-MuLV) proviral genome to construct a retrovirus that allows easy cloning of the...
Hartenstein, B, Schenkel, J, Kuhse, J, Besenbeck, B, Kling, C, Becker, C M, ...
Mutations in inhibitory glycine receptor (GlyR) subunit genes are associated with neuromotor diseases in man and mouse. To use the potential of the mouse mutants as animal models of human disease, we...