Ragg, Hermann, Kumar, Abhishek, Köster, Katharina, Bentele, Caterina, Wang, Yunjie, Frese, Marc-André, ...
Abstract Background Intron gains reportedly are very rare during evolution of vertebrates, and the mechanisms underlying their creation are largely unknown. Previous investigations have shown that,...
The superfamily of serine proteinase inhibitors (serpins) is involved in wide arrays of fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis,...
Ancestry and evolution of a secretory pathway serpin (2008)
Kumar, Abhishek, Ragg, Hermann
Abstract Background The serpin (serine protease inhibitor) superfamily constitutes a class of functionally highly diverse proteins usually encompassing several dozens of paralogs in mammals. Though...
Ragg, Hermann, Lokot, Tatjana, Kamp, Paul-Bertram, Atchley, William R., Dress, Andreas
A combination of three independent biological features, genomic organization, diagnostic amino acid sites, and rare indels, was used to elucidate the phylogeny of the vertebrate serpin (serine...
Phylogenetic Analyses of Amino Acid Variation in the Serpin Proteins (2001)
Atchley, William R., Lokot, Tatiana, Wollenberg, Kurt, Dress, Andreas, Ragg, Hermann
Phylogenetic analyses of 110 serpin protein sequences revealed clades consistent with independent phylogenetic analyses based on exon-intron structure and diagnostic amino acid sites. Trees were...
A new member of the plasma protease inhibitor gene family (1986)
A 2.1-kb cDNA clone representing a new member of the protease inhibitor family was isolated from a human liver cDNA library. The inhibitor, named human Leuserpin 2 (hLS2), comprises 480 amino acids...
UV-induction of chalcone synthase mRNA in cell suspension cultures of Petroselinum hortense
Kreuzaler, Fritz, Ragg, Hermann, Fautz, Erich, Kuhn, David N., Hahlbrock, Klaus
DNAs complementary to poly(A)+ mRNAs from UV-irradiated cell suspension cultures of parsley (Petroselinum hortense) were inserted into pBR322 and used to transform Escherichia coli strain RR1. A...
Bentele, Caterina, Krüger, Olaf, Tödtmann, Ulf, Oley, Mareke, Ragg, Hermann
Lancelets are considered to take a key position in the evolution of lineages leading to vertebrates. Herein, a serpin from the lancelet Branchiostoma lanceolatum, Bl-Spn1, was identified that...
UV-induction of chalcone synthase mRNA in cell suspension cultures of Petroselinum hortense
Kreuzaler, Fritz, Ragg, Hermann, Fautz, Erich, Kuhn, David N., Hahlbrock, Klaus
DNAs complementary to poly(A)+ mRNAs from UV-irradiated cell suspension cultures of parsley (Petroselinum hortense) were inserted into pBR322 and used to transform Escherichia coli strain RR1. A...
Bentele, Caterina, Krüger, Olaf, Tödtmann, Ulf, Oley, Mareke, Ragg, Hermann
Lancelets are considered to take a key position in the evolution of lineages leading to vertebrates. Herein, a serpin from the lancelet Branchiostoma lanceolatum, Bl-Spn1, was identified that...
Brüning, Mareke, Lummer, Martina, Bentele, Caterina, Smolenaars, Marcel M. W., Rodenburg, Kees W., Ragg, Hermann
By alternative use of four RSL (reactive site loop) coding exon cassettes, the serpin (serine protease inhibitor) gene Spn4 from Drosophila melanogaster was proposed to enable the synthesis of...