Hiromu Ito

Subaxial subluxation after atlantoaxial transarticular screw fixation in rheumatoid patients (2009)

Ito, Hiromu, Neo, Masashi, Sakamoto, Takeshi, Fujibayashi, Shunsuke, Yoshitomi, Hiroyuki, Nakamura, Takashi

The most common cervical abnormality associated with rheumatoid arthritis (RA) is atlantoaxial subluxation, and atlantoaxial transarticular screw fixation has proved to be one of the most reliable,...

Remodeling of cortical bone allografts mediated by adherent rAAV-RANKL and VEGF gene therapy

Ito, Hiromu, Koefoed, Mette, Tiyapatanaputi, Prarop, Gromov, Kirill, Goater, J Jeffrey, Carmouche, Jonathan, ...

Structural allograft healing is limited because of a lack of vascularization and remodeling. To study this we developed a mouse model that recapitulates the clinical aspects of live autograft and...

Preferential recruitment of CCR6-expressing Th17 cells to inflamed joints via CCL20 in rheumatoid arthritis and its animal model

Hirota, Keiji, Yoshitomi, Hiroyuki, Hashimoto, Motomu, Maeda, Shinji, Teradaira, Shin, Sugimoto, Naoshi, ...

This report shows that interleukin (IL) 17–producing T helper type 17 (Th17) cells predominantly express CC chemokine receptor (CCR) 6 in an animal model of rheumatoid arthritis (RA). Th17 cells...