Hiroyuki Yoshitomi

Subaxial subluxation after atlantoaxial transarticular screw fixation in rheumatoid patients (2009)

Ito, Hiromu, Neo, Masashi, Sakamoto, Takeshi, Fujibayashi, Shunsuke, Yoshitomi, Hiroyuki, Nakamura, Takashi

The most common cervical abnormality associated with rheumatoid arthritis (RA) is atlantoaxial subluxation, and atlantoaxial transarticular screw fixation has proved to be one of the most reliable,...

Scirtes japonicus (Coleoptera: Scirtidae): New Records from the Hawaii Islands (2008)

Hiroyuki Yoshitomi

Arthritis and pneumonitis produced by the same T cell clones from mice with spontaneous autoimmune arthritis (2008)

Wakasa-Morimoto, Chiaki, Toyosaki-Maeda, Tomoko, Matsutani, Takaji, Yoshida, Ryu, Nakamura-Kikuoka, Shino, Maeda-Tanimura, Miki, ...

SKG mice, a newly established model of rheumatoid arthritis (RA), spontaneously develop autoimmune arthritis accompanying extra-articular manifestations, such as interstitial pneumonitis. To examine...

Description of the Larva of Babalimnichus Masamii M. Satô (Coleoptera: Limnichidae, Thaumastodinae) (2001)

Hiroyuki Yoshitomi, Masataka Satô

The larva of Babalimnichus masamii M. Satô is described. This larva is the first record of the genus and subfamily Thaumastodinae, and is quite easily distinguished from the previously known...

Distinct contribution of IL-6, TNF-α, IL-1, and IL-10 to T cell–mediated spontaneous autoimmune arthritis in mice

Hata, Hiroshi, Sakaguchi, Noriko, Yoshitomi, Hiroyuki, Iwakura, Yoichiroh, Sekikawa, Kenji, Azuma, Yoshiaki, ...

Cytokines play key roles in spontaneous CD4+ T cell–mediated chronic autoimmune arthritis in SKG mice, a new model of rheumatoid arthritis. Genetic deficiency in IL-6 completely suppressed the...

Distinct contribution of IL-6, TNF-α, IL-1, and IL-10 to T cell–mediated spontaneous autoimmune arthritis in mice

Hata, Hiroshi, Sakaguchi, Noriko, Yoshitomi, Hiroyuki, Iwakura, Yoichiroh, Sekikawa, Kenji, Azuma, Yoshiaki, ...

Cytokines play key roles in spontaneous CD4+ T cell–mediated chronic autoimmune arthritis in SKG mice, a new model of rheumatoid arthritis. Genetic deficiency in IL-6 completely suppressed the...

T cell self-reactivity forms a cytokine milieu for spontaneous development of IL-17+ Th cells that cause autoimmune arthritis

Hirota, Keiji, Hashimoto, Motomu, Yoshitomi, Hiroyuki, Tanaka, Satoshi, Nomura, Takashi, Yamaguchi, Tomoyuki, ...

This report shows that highly self-reactive T cells produced in mice as a result of genetically altered thymic T cell selection spontaneously differentiate into interleukin (IL)-17–secreting CD4+...

A role for fungal β-glucans and their receptor Dectin-1 in the induction of autoimmune arthritis in genetically susceptible mice

Yoshitomi, Hiroyuki, Sakaguchi, Noriko, Kobayashi, Katsuya, Brown, Gordon D., Tagami, Tomoyuki, Sakihama, Toshiko, ...

A combination of genetic and environmental factors can cause autoimmune disease in animals. SKG mice, which are genetically prone to develop autoimmune arthritis, fail to develop the disease under a...

Preferential recruitment of CCR6-expressing Th17 cells to inflamed joints via CCL20 in rheumatoid arthritis and its animal model

Hirota, Keiji, Yoshitomi, Hiroyuki, Hashimoto, Motomu, Maeda, Shinji, Teradaira, Shin, Sugimoto, Naoshi, ...

This report shows that interleukin (IL) 17–producing T helper type 17 (Th17) cells predominantly express CC chemokine receptor (CCR) 6 in an animal model of rheumatoid arthritis (RA). Th17 cells...