Humberto Sanchez

Details der Publikationsliste

Zeitraum

2005 - 2009

Anzahl

16

Co-Autoren

RAD50 and NBS1 form a stable complex functional in DNA binding and tethering (2009)

Van Der Linden, Eddy, Sanchez, Humberto, Kinoshita, Eri, Kanaar, Roland, Wyman, Claire

The RAD50/MRE11/NBS1 protein complex (RMN) plays an essential role during the early steps of DNA double-strand break (DSB) repair by homologous recombination. Previous data suggest that one important...

Bacillus subtilis polynucleotide phosphorylase 3'-to-5' DNase activity is involved in DNA repair (2009)

Cardenas, Paula P., Carrasco, Begoña, Sanchez, Humberto, Deikus, Gintaras, Bechhofer, David H, Alonso, Juan C

In the presence of Mn2+, an activity in a preparation of purified Bacillus subtilis RecN degrades single-stranded (ss) DNA with a 3′ → 5′ polarity. This activity is not associated with RecN...

Dynamic structures of Bacillus subtilis RecN-DNA complexes (2008)

Sanchez, Humberto, Cardenas, Paula P., Yoshimura, Shige H., Takeyasu, Kunio, Alonso, Juan C.

Genetic and cytological evidences suggest that Bacillus subtilis RecN acts prior to and after end-processing of DNA double-strand ends via homologous recombination, appears to participate in the...

Bacillus subtilisSbcC protein plays an important role in DNA inter-strand cross-link repair (2006)

Mascarenhas, Judita, Sanchez, Humberto, Tadesse, Serkalem, Kidane, Dawit, Krisnamurthy, Mahalakshmi, Alonso, Juan C, ...

Abstract Background Several distinct pathways for the repair of damaged DNA exist in all cells. DNA modifications are repaired by base excision or nucleotide excision repair, while DNA double strand...

Bacillus subtilis RecN binds and protects 3'-single-stranded DNA extensions in the presence of ATP (2005)

Sanchez, Humberto, Alonso, Juan C.

Bacillus subtilis RecN appears to be an early detector of breaks in double-stranded DNA. In vivo, RecN forms discrete nucleoid-associated structures and in vitro exhibits Mg2+-dependent...

Bacillus subtilis RecN binds and protects 3′-single-stranded DNA extensions in the presence of ATP

Sanchez, Humberto, Alonso, Juan C.

Bacillus subtilis RecN appears to be an early detector of breaks in double-stranded DNA. In vivo, RecN forms discrete nucleoid-associated structures and in vitro exhibits Mg2+-dependent...

Recruitment of Bacillus subtilis RecN to DNA Double-Strand Breaks in the Absence of DNA End Processing

Sanchez, Humberto, Kidane, Dawit, Castillo Cozar, M., Graumann, Peter L., Alonso, Juan C.

The recognition and processing of double-strand breaks (DSBs) to a 3′ single-stranded DNA (ssDNA) overhang structure in Bacillus subtilis is poorly understood. Mutations in addA and addB or null...

The RuvAB Branch Migration Translocase and RecU Holliday Junction Resolvase Are Required for Double-Stranded DNA Break Repair in Bacillus subtilis

Sanchez, Humberto, Kidane, Dawit, Reed, Patricia, Curtis, Fiona A., Cozar, M. Castillo, Graumann, Peter L., ...

In models of Escherichia coli recombination and DNA repair, the RuvABC complex directs the branch migration and resolution of Holliday junction DNA. To probe the validity of the E. coli paradigm, we...

Bacillus subtilis RecN binds and protects 3′-single-stranded DNA extensions in the presence of ATP

Sanchez, Humberto, Alonso, Juan C.

Bacillus subtilis RecN appears to be an early detector of breaks in double-stranded DNA. In vivo, RecN forms discrete nucleoid-associated structures and in vitro exhibits Mg2+-dependent...

Recruitment of Bacillus subtilis RecN to DNA Double-Strand Breaks in the Absence of DNA End Processing

Sanchez, Humberto, Kidane, Dawit, Castillo Cozar, M., Graumann, Peter L., Alonso, Juan C.

The recognition and processing of double-strand breaks (DSBs) to a 3′ single-stranded DNA (ssDNA) overhang structure in Bacillus subtilis is poorly understood. Mutations in addA and addB or null...

The RuvAB Branch Migration Translocase and RecU Holliday Junction Resolvase Are Required for Double-Stranded DNA Break Repair in Bacillus subtilis

Sanchez, Humberto, Kidane, Dawit, Reed, Patricia, Curtis, Fiona A., Cozar, M. Castillo, Graumann, Peter L., ...

In models of Escherichia coli recombination and DNA repair, the RuvABC complex directs the branch migration and resolution of Holliday junction DNA. To probe the validity of the E. coli paradigm, we...

Dynamic structures of Bacillus subtilis RecN–DNA complexes

Sanchez, Humberto, Cardenas, Paula P., Yoshimura, Shige H., Takeyasu, Kunio, Alonso, Juan C.

Genetic and cytological evidences suggest that Bacillus subtilis RecN acts prior to and after end-processing of DNA double-strand ends via homologous recombination, appears to participate in the...

RAD50 and NBS1 form a stable complex functional in DNA binding and tethering

Van Der Linden, Eddy, Sanchez, Humberto, Kinoshita, Eri, Kanaar, Roland, Wyman, Claire

The RAD50/MRE11/NBS1 protein complex (RMN) plays an essential role during the early steps of DNA double-strand break (DSB) repair by homologous recombination. Previous data suggest that one important...

Bacillus subtilis polynucleotide phosphorylase 3′-to-5′ DNase activity is involved in DNA repair

Cardenas, Paula P., Carrasco, Begoña, Sanchez, Humberto, Deikus, Gintaras, Bechhofer, David H, Alonso, Juan C

In the presence of Mn2+, an activity in a preparation of purified Bacillus subtilis RecN degrades single-stranded (ss) DNA with a 3′ → 5′ polarity. This activity is not associated with RecN...